LEDIFOS

Mfd. by :- hetero (Fulfilled By : Magicine Pharma)

ledifos

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Ledifos   

Generic Name: Sofosbuvir and Ledipasvir  

Manufacturer: Hetero  

Dosage Form: Tablet  

Strength: 90mg/400mg   

Composition: Sofosbuvir 400mg + Ledipasvir 90mg   

Packaging: 28 tablets per bottle  

Indication: Hepatitis C  

Storage: Store at room temperature  

Overview 

Ledifos tablet is a combination of two antiviral drugs Sofosbuvir and Ledipasvir. This medicine is used in the treatment of chronic Hepatitis C virus (HCV). It works by blocking the action of a specific protein and preventing its spread in the body. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Do not take this medicine in the wrong way as it may lead to some severe side effects. Avoid the consumption of alcohol during the time of treatment with this medicine.  

Pharmacodynamics  of Ledifos 

Sofosbuvir is used in combination therapy with Ledipasvir antiviral medicine to treat chronic hepatitis C virus (HCV) infected patients with HCV genotypes 1-6 and to treat HCV. After the oral administration, the effect of this medicine can be observed in 2 to 4 hours.  

Usage of Ledifos

Sofosbuvir and Ledipasvir are antiviral medications that are used in combination to treat chronic (when the infection moves into the long-lasting stage) Hepatitis C virus (HCV). This medicine works by removing the virus from the blood over a period of time. Take this medicine with or without food orally once a day. This medication may take some time to show effect. Do not miss your regular dosing schedule. The recommended dose is decided by a doctor according to your previous medical condition and response to the treatment. Do not chew or break the tablet and swallow the whole tablet with a glass of water. 

Side effects of Ledifos

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects  

  • Diarrhea  

  • Nausea  

  • Tiredness  

  • Difficulty in breathing  

  • Cough  

  • Loss of appetite  

  • Muscle pain  

  • Vomiting  

  • Abdominal pain  

  • Fatigue  

  • Anemia  

  • Chills  

  • Unusual weakness  

  • Itching  

  • Blurred vision  

  • Cramps 

  • Allergic reaction  

  • Back pain  

  • Loss of strength  

  • Irregular heartbeat  

  • Chest pain  

  • Irritability  

  • Dizziness  

  • Headache  

  • Insomnia  

  • Pale skin  

  • Mouth ulcers  

Note- immediate medical attention is required if any side effect occurs 

Dosage of Ledifos

Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. This medicine can be taken with or without food.  

Missed dose  of Ledifos

  •  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  of Ledifos

  • In case of an overdose, the doctor will provide emergency medical treatment. 

Warnings of Ledifos

Before starting treatment with this medication, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

 Contraception  

  • Use effective methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  • This medicine is not advisable for use in children and adolescents. 

Warnings for female  

Pregnancy 

  • Do not use this medicine if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of Ledifos

  • This medicine is not recommended in patients who have a history of Hepatitis B infection.  

  • Close monitoring of kidney function is required.  

  • Inform your doctor if you experience any side effects like nausea, fatigue, headache, anemia, and rashes. 

  • Regular monitoring of liver function and the amount of hepatitis C virus (HCV) in your body is required.  

  • Contact your doctor if you have complications in the liver other than HCV infection.  

  • Do not stop taking this medicine without your doctor’s advice. 

Cautions of Ledifos

  • Do not drive or operate heavy machinery.  

  • Do not skip the regular dosing schedule. 

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication.  

  • Do not crush or break the tablet. 

Q1. What is Ledifos (Sofosbuvir and Ledipasvir)?  

Ans. This medicine is used in the treatment of chronic Hepatitis C virus (HCV). It works by removing the virus from the blood over a period of time.  

Q2. How does this medication work? 

Ans.  It works by blocking the action of a specific protein and preventing its spread in the body. 

Q3. What should I avoid while receiving this medicine? 

Ans. Follow your doctor’s instructions about any restrictions on food and other activities.  

Q4. In what strength is it available?  

Ans. It is available in the strength of 90mg/400mg (Sofosbuvir 400mg + Ledipasvir 90mg). 

Q5. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q6. What are the side effects?  

Ans. Some common side effects are:- nausea, fatigue, headache, anemia, rashes, muscle pain, insomnia, dizziness, blurred vision, abdominal pain, vomiting, etc.  

Q7. Can I consume alcohol while taking this medicine?  

Ans. Please consult your doctor before consuming alcohol. 

Q8. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women. 

Q9. How to take this medicine?  

Ans. Take this medicine as prescribed by your doctor. Do not crush or break the tablet. 

Q10. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

Q11. Does this medicine affect kidney function?  

Ans. Please contact your doctor before consuming this drug. 

Q12. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.  

Q13. Does this medicine affect liver function?  

Ans. Please contact your doctor before consuming this drug. 

Q14.  What are the storage conditions?  

Ans.  Store this medicine at room temperature. Keep it away from heat and light.  

Interactions of Ledifos

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.  

Medicine Interactions  

  • Amiodarone  

  • Enzalutamide  

  • St. john’s wort  

  • Carbamazepine  

  • Fosphenytoin  

  • Dexamethasone  

Disease interactions  

  • Immunosuppression  

  • Renal impairment  

  • Hepatic impairment  

Alcohol interaction  

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.  

Contraindications of Ledifos

  • Do not take this medicine if you are allergic to Sofosbuvir and Ledipasvir.  

  • This medicine is not recommended in patients known to be hypersensitive. 

Above Content has been reviewed by Professionals