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Nykron 300/0.5mg Tablet

Nykron 300/0.5mg Tablet

Prescription requiredRx Required

Salt Composition: Netupitant, Palonosetron

Expiry Date: 01/2028

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1 Tablet in Strip

About The Product

Nausea and Vomiting due to chemotherapy

Description

Nykron 300/0.5mg tablet is the prescription based antiemetic combination medication that used in the treatment of vomiting, nausea and other side effects which is caused due to chemotherapy. The medicine contains two active ingredient is Netupitant and Palonosetron.

They belong to the drug class of NK1 receptor antagonists and 5-HT3 receptor antagonists, respectively, and work together to prevent chemotherapy-induced nausea and vomiting. Doctor's prescription is necessary while taking the medication for correct dose and duration of the tablet.


Uses

Reduced nausea and vomiting due to chemotherapy


Side Effects

  • Headache
  • Fatigue or weakness
  • Constipation
  • Skin redness
  • Indigestion
  • Difficulty breathing
  • Swollen face/ tongue
  • Rash
  • Muscle stiffness
  • Rapid heart rate


How To Use

  • Nykron 300/0.5mg tablet should be taken one hour before start of chemotherapy.
  • The medicine is taken with or without food at the same time everyday to improve the absorption level in the body.
  • Hence, the correct dose and duration of the medicine is only administered by the healthcare provider to enhance the effectiveness of the treatment.

How It Works

Nykron 300/0.5mg tablet is antiemetic combination medication that contain two active ingredient Netupitant that blocks neurokinin‑1 (NK1) receptors, which helps to prevent delayed nausea and vomiting. While Palonosetron blocks 5‑HT3 (serotonin) receptors that reduce acute nausea and vomiting during and soon after chemotherapy.

They both work together and provide long lasting protection from such types of side effects.

Safety Advice

Alcohol
Alcohol is strictly prohibited while taking Nykron 300mg tablet as this may interrupt with the treatment. Discuss with the doctor for any query.
Pregnancy
Nykron 300/0.5mg tablet should be taken during pregnancy if it is correctly prescribed under doctor guidance.
Breast Feeding
Women who breastfeed their child should consult a healthcare expert as Nykron 300mg may harm the baby in various ways. It is better to seek medical advice before taking this medication.
Driving
Nykron 300/0.5mg tablet can cause dizziness, fatigue or headache and other side effects. Patients should avoid driving or heavy machinery if they feel any symptoms.
Kidney
Patient with kidney disease should take precaution while taking Nykron 300/0.5mg tablet.
Liver
Patient with liver problems should inform their doctor while taking Nykron 300/0.5mg tablet as dose adjustment should be needed.

FAQs

Nykron 300/0.5mg tablet reduce symptoms such as nausea, vomiting and other symptoms after chemotherapy.

It gives patients relief from side effects and helps improve their comfort during cancer treatment.

References

  • Lorusso, V., Russo, A., Giotta, F., & Codega, P. (2020). Management of chemotherapy-induced nausea and vomiting (CINV): a short review on the role of netupitant-palonosetron (NEPA). Core evidence, 21-29.
  • Shirley, M. (2021). Netupitant/palonosetron: a review in chemotherapy-induced nausea and vomiting. Drugs, 81(11), 1331-1342.
  • Keating, G. M. (2015). Netupitant/palonosetron: a review in the prevention of chemotherapy-induced nausea and vomiting. Drugs, 75(18), 2131-2141.
  • Aapro, M., Jordan, K., Scotté, F., Celio, L., Karthaus, M., & Roeland, E. (2022). Netupitant-palonosetron (NEPA) for preventing chemotherapy-induced nausea and vomiting: from clinical trials to daily practice. Current Cancer Drug Targets, 22(10), 806-824.
  • Lorusso, V. (2016). Management of chemotherapy-induced nausea and vomiting by risk profile: role of netupitant/palonosetron. Therapeutics and Clinical Risk Management, 917-925.

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