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Pazinib 200mg Tablet

Pazinib 200mg Tablet

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Salt Composition: Pazopanib (200mg)

Expiry Date: 01/2028

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30 Tablet

About The Product

used in the treatment of kidney cancer and soft tissue sarcoma.

Pazinib 200mg Tablet is a second-generation multi targeted tyrosine kinase inhibitor as it contains active ingredient Pazopanib. It is an anticancer medicine prescribed to treat metastatic soft tissue sarcoma and kidney cancer.

This medicine is specifically suitable for patients with prior chemotherapy and is available only on prescription. It works by reducing tumor blood flow and increasing cell apoptosis (cancer cell death). Take it as prescribed by the doctor at fix time each day to get better results.


Uses

  • Kidney cancer
  • Soft tissue sarcoma

Side Effects

Every medicine has some side effects that manage on their own as your body gets used to the medicine, but some people may rarely experience severe side effects. In that case, the patient should contact the doctor immediately.

Some common side effects of  Pazinib 200mg Tablet   include:

  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Breathlessness
  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle or joint) pain
  • Fatigue
  • Change in color of hair
  • Diarrhea

How To Use

  • The Dosage of the tablet is usually decided by the doctor based on the health condition of the patient.
  • Pazinib 200mg Tablet should be taken on empty stomach at the same time every day.
  • Take this drug as prescribed by the doctor.
  • Swallow tablet as a whole with water and don't chew, break, or crush it.

How It Works

Pazinib 200mg Tablet is an anti-cancer medication with active ingredient Pazopanib. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells.

It also reduces the growth of new blood vessels within the tumor. This is how it works to slow down the progression of cancer.

Safety Advice

Alcohol
Avoid the consumption of alcohol while taking Pazinib 200mg, as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms.
Pregnancy
Do not take Pazinib 200mg Tablet without consulting the doctor in case of pregnancy, as it can be unsafe to take it during this period.
Breast Feeding
Breastfeeding women should discuss the potential risks and benefits of the Pazinib 200mg Tablet with their healthcare provider before starting treatment.
Driving
Pazinib 200mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
Kidney
Pazinib 200mg Tablet is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.
Liver
Share your medical history with the doctor before starting the Pazinib 200mg Tablet. Do not take it without consulting a doctor if you have any liver related issue.

FAQs

Pazinib 200mg is used in the treatment renal cell carcinoma (kidney cancer).

It is also prescribed to treat metastatic soft tissue sarcoma.

Reference

  • Van Der Graaf, W. T., Blay, J. Y., Chawla, S. P., Kim, D. W., Bui-Nguyen, B., Casali, P. G., ... & Hohenberger, P. (2012). Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet, 379(9829), 1879-1886.     
  • Pick, A. M., & Nystrom, K. K. (2012). Pazopanib for the treatment of metastatic renal cell carcinoma. Clinical therapeutics, 34(3), 511-520.
  • Schutz, F. A., Choueiri, T. K., & Sternberg, C. N. (2011). Pazopanib: Clinical development of a potent anti-angiogenic drug. Critical reviews in oncology/hematology, 77(3), 163-171.
  • Miyamoto, S., Kakutani, S., Sato, Y., Hanashi, A., Kinoshita, Y., & Ishikawa, A. (2018). Drug review: pazopanib. Japanese Journal of Clinical Oncology, 48(6), 503-513.
  • Sonpavde, G., & Hutson, T. E. (2007). Pazopanib: a novel multitargeted tyrosine kinase inhibitor. Current oncology reports, 9(2), 115-119.     

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