How should I take Rapamune tablet?

Rapamune is taken with or without food with a whole glass of water at the fixed time every day to enhance the effectiveness of the medication.

Can I drink alcohol while taking Rapamune 1mg tablet?

Avoid alcohol and limit it while taking Rapamune 1mg tablet, as it can increase the risk of liver problems and worsen the side effects.

What precautions should I watch while taking Rapamune 1mg tablet?

Avoid sudden stopping, avoid alcohol, consult the doctor while using the medication, and regular blood tests are important.

What is the salt formation of Rapamune 1mg tablet?

Rapamune 1mg tablet active ingredient is Sirolimus, which works as an immunosuppressant by inhibiting the mTOR pathway, thereby preventing the T cell activation and reducing the risk of organ rejection.

Buy Rapamune 1mg Tablet Online: Price, 0% Discount, Uses, and Side Effects

Name: Rapamune 1mg Tablet
Brand: Rapamune
Price: 3700 INR
Availability: InStock
Rating: 4 (6 reviews)

Description

Rapamune 1mg tablet is a prescription-based medication that should be taken under a doctor's guidance. The medication is used to help prevent organ rejection in kidney transplantation. Its salt composition is Sirolimus. It acts as an immunosuppressant by inhibiting the mTOR pathway and reducing T cell activation and proliferation. It belongs to the group of mTOR inhibitors (immunosuppressive agents). Regular monitoring by the healthcare professional is necessary to ensure safe and effective treatment. The patient should follow the prescribed dose exactly and report any unusual symptoms or side effects immediately.

Uses

Help to prevent organ rejection in patients with kidney transplantation

Side Effects

Every medication has several side effects that may vary from person to person and should be monitored by a healthcare professional. Common ones include:

Fatigue or weakness
Nausea and vomiting

Rash
Infrequent, absent, or heavy periods
Rapid heart rate
High blood sugar
Joint pain
Acne
Swelling of the body, including feet and hands

Headache
Fever, pain
High blood pressure and cholesterol levels
Constipation, diarrhea, stomach pain

How To Use

Rapamune 1mg tablet should be taken with a whole glass of water with or without food at the same time every day.
Do not self-administer as it can cause side effects.
Always follow the recommended dosage and never adjust or skip doses without consultation with a healthcare professional, as this can increase the risk of organ rejection or other complications.

How It Works

After transplantation, the immune system sees the new organ as foreign and tries to attack it. Rapamune 1mg tablet weakens this immune response by inhibiting the activity and growth of immune cells that cause rejection.

This helps the body accept and keep the transplanted organ working well.

Safety Advice

Alcohol

Alcohol can increase the risk of side effects. It is best to avoid alcohol while using Rapamune 1mg tablet.

Pregnancy

Rapamune 1mg tablet can harm the unborn baby. Inform the doctor immediately when pregnancy occurs.

Breast Feeding

It is not for sure but sirolimus may pass into breast milk and could harm the baby in many ways. Stop breastfeeding while on this medication.

Driving

Driving is usually safe and does not cause any drowsiness while using Rapamune 1mg. If the patient feels weak, dizzy, or unwell, then avoid driving and operating machines.

Kidney

Regular kidney test and drug level monitoring are necessary as Rapamune 1mg can affect kidney function while transplanting.

Liver

Dose adjustment may be needed in people with liver disease when using Rapamune tablet. Regular liver function tests are usually required.

FAQs

Rapamune 1mg is used to prevent organ rejection after kidney transplantation by reducing the immune system's attacks on the new organ.

References

Basa-Dénes, O., Angi, R., Kárpáti, B., Jordán, T., Ötvös, Z., Erdősi, N., ... & Glavinas, H. (2019). Dose escalation study to assess the pharmacokinetic parameters of a nano-amorphous oral sirolimus formulation in healthy volunteers. European Journal of Drug Metabolism and Pharmacokinetics, 44(6), 777-785. https://pubmed.ncbi.nlm.nih.gov/31089971/
Wyeth, T. M. (2017). Pr RAPAMUNE®. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021083s059,021110s076lbl.pdf
Tejani, A., Alexander, S., Ettenger, R., Lerner, G., Zimmerman, J., Kohaut, E., & Briscoe, D. M. (2004). Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune®, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis 1. Pediatric transplantation, 8(2), 151-160. https://pubmed.ncbi.nlm.nih.gov/15049795/
Tao, C., Wen, X., Zhang, Q., & Song, H. (2019). Solid sirolimus self-microemulsifying drug delivery system: development and evaluation of tablets with sustained release property. Iranian Journal of Pharmaceutical Research: IJPR, 18(4), 1648. https://pmc.ncbi.nlm.nih.gov/articles/PMC7059041/
Business, B. (2017). 7.7. 1 mTOR Inhibitors Rapamune®(Sirolimus) and AfinitorⓇ. Translating Molecules into Medicines: Cross-Functional Integration at the Drug Discovery-Development Interface, 25, 258.

Rapamune 1mg Tablet

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