Regonat 40mg Tablet
Prescription Required
Marketed By
Natco
Pack of
28 Tablet
Salt Composition
Regorafenib
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
Regonat 40mg Tablet belongs to the category of anticancer medicines. These medicines are primarily used to treat patients diagnosed with colon and rectum cancer. The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Regonat Tablet is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Rectal Cancer, Colorectal Cancer
Uses
Regonat 40 mg tablet is used in the treatment of:
1. Colorectal cancer has started to spread to other parts of the body
2. Gastrointestinal stromal tumors (GIST) (a type of stomach and bowel cancer)
3. Liver cancer in adult patients who have already undergone treatment with Sorafenib
Side Effects
The human body shows undesired symptoms after taking Regonat 40mg Tablet. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Regonat Tablet are mentioned below:
Rash
Fever
Hair loss
Diarrhea
Infection
Body pain
Weakness
Headache
Weight loss Low appetite
Changed voice
Low blood count
Nausea & Vomiting
High Blood pressure
Infection of the stomach
Inflammation of the mouth
Unusual bleeding and bruising
Increased level of liver enzymes
Low levels of platelets and WBCs, Severe side effects
Chest pain
Thyroid problem
Bilirubin in urine
Skin detachment
Secondary cancer
Severe allergic reactions
High level of uric acid in the blood
How To Use
Regonat 40mg Tablet is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert.
How It Works
Regonat 40mg Tablet is an anticancer medicine that belongs to the drug class of Tyrosine kinase inhibitors. This drug inhibits the formation of blood vessels that are responsible for the blood supply to the tumor cells. That’s how it slows down and stops the growth of cancer cells and also prevents their spread to nearby organs.
Safety Advice

Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Regonat 40mg Tablet. It is advised to consult your doctor for further information.

Pregnancy
consult your doctor
Regonat 40mg Tablet may be considered unsafe during pregnancy. Please consult your doctor in such condition.

Breast Feeding
consult your doctor
Regonat 40mg Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.

Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Regonat 40mg Tablet.

Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Regonat 40mg Tablet.

Liver
safe if prescribed
Inform your doctor before starting Regonat 40mg Tablet if you have liver disease to avoid any serious side effects.
Missed Doses
It is advised not to miss any scheduled dosage of Regonat 40mg Tablet. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
It is advised to use effective birth control ways and avoid pregnancy during the treatment with Regonat 40mg Tablet.
A person should avoid smoking while undergoing treatment with Regonat 40mg Tablet. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Regonat 40mg Tablet.
Skin becomes extremely sensitive after taking Regonat 40mg Tablet. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Regonat 40mg Tablet, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Regonat 40mg Tablet. Consult your doctor if it doesn't stop or if blood appears in your stools.
If you experience any kind of symptoms after taking Regonat 40mg Tablet like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
FAQs
This medicine is given to adults diagnosed with Colorectal cancer, Gastrointestinal stromal tumors, and Liver cancer.
Regonat Tablet is taken orally with or without food as per the doctor's advice. It is consumed at the same time each day for better results. It is recommended not to crush, chew, or split the capsules; take them as a whole.
The most common side effects of this medicine include Diarrhea, Headache, Tiredness, Mouth sores, Muscle or joint pain, Stomach pain, and difficulty breathing. It is advised to go for regular liver function tests to examine the liver function.
People diagnosed with severe liver and kidney disorders are advised to consult their healthcare professionals before taking this medicine.
Yes, regonat is given alone or in combination with other medicines to treat other cancer or to increase treatment effectiveness.
When other drugs and therapies fail to treat stomach, colon, or rectal cancer, Regonat 40 mg tablets are used as chemotherapy.
No, because grapefruit juice reduces the medication's effectiveness, patients are recommended not to consume it while taking this medication.
Due to its adverse impacts on the developing baby, this medicine should not be used by anybody who is planning to become pregnant or who is already pregnant.
Trusted Medicines, Delivered Worldwide
At our pharmacy, your health is our top priority. All of our medicines are safe, effective, and approved by leading health authorities. We partner exclusively with reliable and reputable manufacturers, ensuring the highest quality standards in every product we deliver.
Enjoy the convenience of fast home delivery, secure packaging, and affordable prices—plus special discounts on bulk orders. We’re proud to offer international shipping to a wide range of countries across Asia, Europe, Africa, the Americas, and beyond, making trusted healthcare accessible no matter where you are.
Whether you're a patient or a healthcare provider, you can order with confidence and compassion. Our goal is to ensure that quality healthcare reaches everyone, everywhere.
We currently ship to:
Barbados, Haiti, Trinidad and Tobago, Mexico, Bahamas, Ecuador, Peru, Chile, Brazil, Colombia, Philippines, U.K., USA, Kuwait, Saudi Arabia, UAE, Oman, Qatar, Japan, Ireland, Russia, China, France, Australia, Lithuania, Nigeria, Romania, Algeria, Canada, Singapore, Thailand, Hong Kong, Bahrain, Jordan, Indonesia, Hungary, Moldova, Bulgaria, Azerbaijan, Congo, Ethiopia, Lebanon, Morocco, Mozambique, South Korea, Sri Lanka, Belarus, Mongolia, Malaysia, Vietnam, Tunisia, Zambia, and Israel.
Experience the quality everyone’s talking about – order today!
Reference
Kato, T., Kudo, T., Kagawa, Y., Murata, K., Ota, H., Noura, S. & Eguchi, H. (2023). Phase II dose titration study of regorafenib in progressive unresectable metastatic colorectal cancer. Scientific Reports, 13(1), 2331.
Ma, W., Li, Y., Lu, Y., Liang, Z., Yu, H., Han, J. & Cheng, J. (2025). A Multicenter Retrospective Study: Impact of First-Line Treatment Strategies on Second-Line Efficacy and Safety of Regorafenib with or Without PD-1 Inhibitors in Unresectable Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma, 2123-2137.
Skårderud, M. R., Polk, A., Vistisen, K. K., Larsen, F. O., & Nielsen, D. L. (2022). Efficacy and safety of regorafenib in the treatment of metastatic colorectal cancer: a systematic review. Cancer treatment reviews, 62, 61-73.
Yan, T., Huang, C., Peng, C., Duan, X., Ji, D., Duan, Y.& Lu, Y. (2023). A multi-center retrospective study on the efficacy and safety of regorafenib vs. regorafenib combined with PD-1 inhibitors as a second-line therapy in patients with advanced hepatocellular carcinoma. Annals of Translational Medicine, 11(2), 109.
Zhang, W., Zhao, Y., Ma, G., Zhang, Y., Guo, Y., & Chen, Z. (2023). Efficacy and safety of regorafenib alone or in combinations in the second-line setting for advanced hepatocellular carcinoma: A multicenter real-world study. Journal of Gastrointestinal Oncology, 12(4), 1549.
Zhao, J., Guo, Y., Feng, T., Rong, D., Kong, X., Huang, T. & Xia, Y. (2023). Efficacy and safety of regorafenib in combination with immune checkpoint inhibitor therapy as second-line and third-line regimen for patients with advanced hepatocellular carcinoma: A retrospective study. Journal of Gastrointestinal Oncology, 14(6), 2549.
Related Products
MARKETER DETAILS
Natco
DISCLAIMER
The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.

