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dr. reddy
28 tablet
Sofosbuvir
Keep in cold place
Delivering To:
Overview
Resof 400mg (Sofosbuvir) tablets are used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus in adults. It is advised to take Resof 400mg tablet exactly as the healthcare provider tells.
Hepatitis C
Sofosbuvir acts against the Hepatitis C Virus. It is categorized as a direct-acting antiviral agent (DAA). At a dose (3 times the recommended dose), Sofosbuvir does not prolong QTc to any clinically relevant extent. Sofosbuvir is specifically a nucleotide analog inhibitor. It inhibits HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase. Sofosbuvir is incorporated into HCV RNA by the NS5B polymerase, following intracellular metabolism to form the pharmacologically active uridine analog triphosphate (GS-461203). Sofosbuvir prevents HCV viral implication and replication by binding to the two Mg2+ ions that are present in HCV NS5B polymerase's GDD active site motif, thereby working to prevent further replication of HCV genetic material.
Most side effects of Resof tabletsdo not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Tiredness
Fever
Difficulty in breathing
Cough
Lower back pain
Headache
Skin rash
Irritability
Insomnia
Vomiting
Diarrhea
Nausea
Loss of appetite
Muscle pain
Cramps
Anemia
Your healthcare provider will decide your dose and the duration of Resof tablets. Please do not alter or manipulate the dose strength, unless your healthcare provider tells you.
In case of an overdose, seek emergency medical help.
Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
consult your doctor
Do not take Resof tablets without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take Resof tablets without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
If you miss a dose of Resof tablets, try to take it as soon as you remember. However, if it is already time for the next dose, do not take the missed dose as it will double the dose strength.
Resof 400mg tablet is used with other medicines in the treatment of chronic Hepatitis C Virus in adults.
Side effects of Resof can be fever, nausea, anemia, diarrhea, difficulty in breathing, muscle cramps, and insomnia. In case you experience these or any other side effects, make sure to consult your healthcare provider.
Store at room temperature (10-30°C). Keep away from direct light, moisture, heat, and children.
While consuming Resof 400mg tablet, avoid drinking alcohol.
Resof 400mg tablet is safe if prescribed during breastfeeding. Kindly consult your healthcare provider first.
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dr. reddy
Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.