Mfd. by :- Solu Clini Pharm Pvt Ltd (Fulfilled By : Magicine Pharma)



Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Medicine details

Brand name - Resof
Generic name - Sofosbuvir
Company - Dr. Reddy''s Laboratory
Salt composition - Sofosbuvir
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (Tablet)
Strength - 400mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Prescription needed - Yes
Active ingredient - Sofosbuvir 400mg
Indication - Used in the treatment of Chronic Hepatitis C Virus (HCV) infection


Resof 400mg (Sofosbuvir) tablets are used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus in adults. It is advised to take Resof 400mg tablet exactly as the healthcare provider tells. 


Sofosbuvir acts against Hepatitis C Virus. It is categorized as a direct-acting antiviral agent (DAA). At a dose (3 times the recommended dose), Sofosbuvir does not prolong QTc to any clinically relevant extent. Sofosbuvir is specifically a nucleotide analog inhibitor. It inhibits HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase. Sofosbuvir incorporates into HCV RNA by the NS5B polymerase, following intracellular metabolism in order to form the pharmacologically active uridine analog triphosphate (GS-461203). Sofosbuvir prevents HCV viral implication and replication by binding to the two Mg2+ ions that are present in HCV NS5B polymerase's GDD active site motif, thereby working to prevent further replication of HCV genetic material.


The active ingredient of Resof 400mg is Sofosbuvir. Sofosbuvir is used to treat viral infection of the liver. It helps to lower the multiplication of HCV.

Usage of medicine

Resof 400mg tablets are used in the treatment of chronic Hepatitis C Virus in adults, when administered with other supporting medications.

Alternate brands

  • Sofocure tablet

  • Sovihep tablet

  • Hepcvir tablet

  • Hepcinat tablet

  • Sofab tablet

  • Sofovir tablet

Side effects

Common side effects

  • Tiredness

  • Fever  

  • Difficulty in breathing

  • Cough

  • Lower back pain

  • Headache

  • Skin rash

  • Irritability

  • Insomnia 

  • Vomiting

Serious side effects

  • Diarrhea

  • Nausea

  • Loss of appetite

  • Muscle pain 

  • Cramps

  • Anemia 


Normal dose

Your healthcare provider will decide your dose, and duration of your dose. Please do not alter or manipulate the dose strength, unless your healthcare provider tells you.

Missed dose

If you miss a dose, try to take it as soon as you remember. However, if it is already the time for the next dose, do not take the missed dose as it will double the dose strength.


In case of overdose, seek emergency medical help.


Warning and precautions

  • Resof 400mg tablets should not be taken without doctor’s prescription.

  • Make sure to tell your healthcare provider about all the medicines you already take, along with your medical history.

  • Avoid drinking alcohol.

  • Do not alter or manipulate the dose strength on your own, unless your healthcare provider tells you.

  • Make sure to keep a note of the minor side effects you experience, and consult your healthcare provider for the same.

  • During pregnancy or breastfeeding, kindly ask your healthcare provider if Resof is safe for you or not. Do not administer without doctor’s prescription.

  • Do not crush, chew or break the tablet. Swallow it as a whole.

  • Drink plenty of water.


You should not take Resof 400mg tablet unless your healthcare provider tells you, if you are suffering from:

  • Liver or/and kidney disease


  • Drug allergy


Q1- What is Resof?

A- Resof 400mg tablet is used with other medicines in the treatment of chronic Hepatitis C Virus in adults.

Q2- In what strength is it available?

A- Resof tablets are available in the strength of 400mg.

Q3- What are the possible side effects of Resof (Sofosbuvir)?

A- Side effects of Resof can be fever, nausea, anemia, diarrhea, difficulty in breathing, muscle cramps and insomnia. In case you experience these or any other side effects, make sure to consult your healthcare provider.

Q4- What are the storage conditions for Resof?
A- Store at room temperature (10-30°C). Keep away from direct light, moisture, heat and children.

Q5- What should I avoid while consuming Resof 400mg?

A- While consuming Resof 400mg tablet, avoid drinking alcohol.

Q6- Can I take this medicine during pregnancy?

A- Make sure to ask your healthcare provider before taking this medicine.

Q7- Can I take this medicine during breastfeeding?

A- Resof 400mg tablet is safe if prescribed during breastfeeding. Kindly consult your healthcare provider first.

Q8- Can I drive after taking Resof?

A- Resof (Sofosbuvir) can cause dizziness. Therefore, it is advised to not drive or operate heavy machines.

Q9- Can I take this medicine in kidney disease?

A- Before taking Resof 400mg tablet, make sure to ask your healthcare provider first. Resof should be administered with caution in patients with kidney disease.

Q10- Can I take this medicine in liver disease?

A- Resof is safe if prescribed in liver disease. Please ask your doctor.

Q11- Can I consume alcohol with this medicine?

A- Avoid consumption of alcohol.

Q12- What are the self-care tips?

A- Drink plenty of water. 

Q13- Is Resof 400mg tablet habit forming?

A- No, it is not habit-forming.


Above Content has been reviewed by Professionals