Marketed By
samarth
Pack of
120 Tablet in Bottle
Salt Composition
Abiraterone Acetate
Storage
Keep in cold place
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Samtica 250mg Tablet
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Overview
Samtica 250mg Tablet is a prescription-based anticancer medicine used to treat early-stage prostate cancer in adult men that has spread to nearby organs. The prostate is a walnut-sized gland present in the male reproductive system. Samtica Tablet comes under the category of hormonal therapy. The active ingredient of this medicine is abiraterone acetate. This medicine works by lowering the male sex hormones in the body.
Indication
Prostate Cancer
Description
Samtica 250mg Tablet is a hormonal therapy medication prescribed to treat early-stage prostate cancer in adult men. It is usually taken with a steroid to lower the side effects of other anticancer medicines when taken together. This drug prevents the normal secretion of male sex hormones by inhibiting the actions of the enzyme. Samtica Tablet also relaxes the associated symptoms of prostate cancer, such as difficulty in passing the urine. This tablet can also be a combination drug in chemotherapy to increase its effectiveness. When this medicine is given for an early stage of prostate cancer, it is given with testosterone-lowering treatment. Inform your doctor if you are taking any kind of medications or nutraceuticals. This kind of medicine can react with Samtica 250mg Tablet and may result in some undesirable effects. Before taking this tablet, share with your doctor if you have high blood pressure, heart disease, kidney, or liver problems. It is advised to use reliable methods of birth control and contraceptive pills to avoid pregnancy while under treatment. This tablet should not be given to pregnant and breastfeeding women, as it may pass through the mother and harm the baby. This medicine should not be taken with Ra-223, which is another anticancer medicine to treat prostate cancer.
Side Effects
Like other anticancer medicines, Samtica 250mg Tablet also has some common to severe side effects. These are undesired symptoms observed in the body after taking this tablet. Usually, they disappear with time as the body adjusts to the medicine. These adverse effects don't need special medical attention, but if you observe them continually, talk to your medical expert. Some of them are listed below:
Common side effects:
Vomiting
Diarrhea
Joint pain
Fatigue
Cough
High BP
Constipation
Chest pain
Rashes
Irregular & fast heart rate
Severe side effects:
Swelling
Urinary Tract Infection
Low blood count
Blood in urine
Decreased potassium level in blood
How To Use
Samtica 250mg Tablet is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert.
How It Works
Samtica 250mg Tablet is an anticancer medicine which is used to treat prostate cancer. This drug blocks the action of the enzyme CYP17, which signals the production of sex hormones androgen and testosterone in males. That way, it slows down the growth and replication of the cancer cells. Eventually, it inhibits the cancer cells from spreading to other parts of the body and leads to their death.
Safety Advice

Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Samtica 250mg Tablet. It is advised to discuss with your doctor for further information.

Pregnancy
consult your doctor
Samtica 250mg Tablet may be considered unsafe during pregnancy. Please consult your doctor in such a condition.

Breast Feeding
consult your doctor
Samtica 250mg Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.

Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking the Samtica 250mg Tablet.

Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Samtica 250mg Tablet.

Liver
safe if prescribed
Inform your doctor before starting Samtica 250mg Tablet if you have liver disease to avoid any serious side effects.
Missed Doses
It is advised not to miss any scheduled dosage of Samtica 250mg Tablet. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately.
Quick Tips
Samtica 250mg Tablet is usually taken with another medicine, prednisolone to reduce unwanted side effects.
Inform your doctor if you have diabetes or any heart, liver, and kidney problems before taking Samtica 250mg Tablet.
Samtica 250mg Tablet contains lactose and sodium. Share with your physician if you have lactose intolerance.
Use reliable methods of birth control and contraceptive pills to avoid pregnancy while under treatment with Samtica 250mg Tablet.
Your medical professional must monitor your blood sugar & pressure, potassium level, and liver function tests at regular intervals. Taking the Samtica 250mg Tablet can cause fluctuations in their levels.
FAQs
After taking Samtica 250mg Tablet, your healthcare expert must measure liver enzyme every two weeks for the first three months during treatment and monthly thereafter. If the level seems to rise, your doctor may temporarily discontinue the Samtica tablet.
Samtica 250mg Tablet is not considered safe to use for patients with a history of liver disease. It may worsen the condition. In rare cases, it can cause liver failure that leads to death. It is advised to consult your healthcare provider before taking this medicine.
Samtica 250mg Tablet does not completely cure prostate cancer but improves the quality of life of the patient. It reduces the chances of side effects due to other anticancer medicines. This hormonal therapy drug lowers the production of male sex hormones; testosterone and androgen. Eventually, it slows down the cancer to spread to other organs in the body.
No, Samtica 250mg Tablet is a hormonal therapy drug, not a chemotherapy drug. This drug treats prostate cancer and prevents the production of male sex hormones. Eventually, it slows down the abnormal growth and replication of the cancer cells.
Samtica 250mg Tablet is given to patients as a hormonal therapy drug. The doctor prescribes this tablet for treating early-stage prostate cancer in men that has spread to other nearby parts of the body.
Reference
De Bono, J. S., Logothetis, C. J., Molina, A., Fizazi, K., North, S., Chu, L., & Scher, H. I. (2021). Abiraterone and increased survival in metastatic prostate cancer. New England Journal of Medicine, 364(21),1995-2005.
Fizazi, K., Tran, N., Fein, L., Matsubara, N., Rodriguez-Antolin, A., Alekseev, B. Y. & Chi, K. N. (2024). Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. New England Journal of Medicine, 377(4), 352-360.
Ghose, A., Lapitan, P., Apte, V., Ghosh, A., Kandala, A., Basu, S., & Banna, G. L. (2024). Antibody drug conjugates in urological cancers: a review of the current landscape. Current Oncology Reports, 26(6),633-646.
Ryan, C. J., Smith, M. R., Fizazi, K., Saad, F., Mulders, P. F., Sternberg, C. N. & Rathkopf, D. E. (2025). Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study. The Lancet Oncology, 16(2),152-160.
Szmulewitz, R. Z., Karrison, T., Stadler, W. M., & Ratain, M. J. (2023). Low-Dose Abiraterone With Food: Rebutting an Editorial. Journal of Clinical Oncology, 36(30),3060-3061.
Szmulewitz, R. Z., Peer, C. J., Ibraheem, A., Martinez, E., Kozloff, M. F., Carthon, B., & Ratain, M. J. (2025). Prospective international randomized phase II study of low-dose abiraterone with food versus standard dose abiraterone in castration-resistant prostate cancer. Journal of Clinical Oncology, 36(14),1389-1395.
Thakur, N., Singh, P., Bagri, A., Srivastava, S., Dwivedi, V., Singh, A. & Dholpuria, S. (2024). Therapy resistance in prostate cancer: mechanism, signaling, and reversal strategies. Exploration of Targeted Anti-tumor Therapy, 5(5),1110.
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samarth
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