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Sofocure 400mg Tablet

Sofocure 400mg Tablet

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Salt Composition: Sofosbuvir

Expiry Date: 01/2028

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28 tablet

About The Product

Hepatitis C

Sofocure tablet is an antiviral medicine. This medicine is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults. Sofocure should be taken exactly as prescribed by the healthcare provider (in dose and duration). It works by lowering the multiplication of the virus and helps in the removal of the virus from the blood over a period of time.

Description

​ Sofosbuvir inhibits the hepatitis C NS5B protein. Sofosbuvir appears to have a high barrier to the development of resistance.

Sofosbuvir is a prodrug of the Protide type, whereby the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation.

Dephosphorylation then creates the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours.

Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery. ​

Side Effects

Sofocure tablets may cause certain side effects. If side effects occur after administration or last longer than usual, contact your healthcare professional.

Tiredness 

Confusion

Dizziness 

Headache

Weakness

Joint pain

Fever

Chills

Muscle pain

Irritability 

Skin rash

Itching

Fatigue 

Insomnia

How To Use

  • ​ Take the Sofocure tablet exactly as your healthcare provider tells you.
  • Do not alter the dose strength.
  • Do not chew, crush, or break the tablet.
  • Swallow the tablet as a whole.
  • Seek emergency medical attention in case of overdose. ​

Safety Advice

Alcohol
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
Do not take Sofocure tablet without consulting the doctor, in case of pregnancy.
Breast Feeding
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
Do not take Sofocure tablet without a doctor's consultation in case of kidney problems.
Liver
Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

  • It is advisable not to miss any dose.
  • In case you miss a dose of Doxilyd 10mg injection consult your doctor soon.
  • Missing the dose will impact the overall health of the patients.
  • So, it is always advisable to follow the prescription of the doctor strictly.

FAQs

​ Sofocure is an antiviral medication, used with other medicines to treat chronic Hepatitis C Virus.

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