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Aprazer Healthcare Pvt Ltd
28 Tablet
Sofosbuvir
Keep in cold place
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Overview
Sofokast 400mg Tablet belongs to the category of Hepatitis medicines. These medicines are primarily used to treat patients diagnosed with the hepatitis C virus (HCV) infection. The active ingredient of the Sofokast is Sofosbuvir, which belongs to the drug class of direct-acting antivirals (DAAs). It is taken orally with or without food as per the doctor's advice. Sofokast treats specific genotypes of hepatitis C in certain people, and in some cases also used for HIV treatment, whereas it is not a treatment for HIV or AIDS.
Hepatitis C, Viral Infection
Like most anticancer drugs, Sofokast 400mg Tablet may cause some adverse effects on the body during the treatment. These can vary from mild to severe depending on the dose and the patient’s health condition.
Common side effects include:
Fever
Nausea
Joint pain
Vomiting
Fatigue
Abdominal pain
Poor appetite
Itching
Dark yellow urine & stools
Jaundice
Pale skin
Unusual tiredness
Feeling light-headed
Difficulty breathing
Cold hands and feet
Inform your doctor immediately if you experience any persistent or unusual side effects.
Sofokast 400mg Tablet is a prescription-based hepatitis drug that should be administered orally. It is advised to take this tablet with or without food as per the doctor's advice. It should be taken at the same time every day for effective results. The required dosage and duration of the medicine are decided by the doctor as per medical history, age, health condition, and the body's response to the treatment. Taking it in the wrong way or overdosing can cause severe side effects. It may take weeks for patients to notice the benefits of the medicine. So do not stop taking this tablet until your doctor says to do so. Sofokast is given as a combination therapy with other antiviral medications to treat chronic hepatitis C in adults, and it should not be used alone.
The active ingredient of the Sofokast is Sofosbuvir, which belongs to the drug class of direct-acting antivirals (DAAs). Sofokast Tablet works by eliminating the virus completely from the human body. In this way, it prevents the infection from spreading to other parts of the body. This tablet blocks the protein required for replication and assembly of new virus particles. Once this protein gets blocked, the virus multiplication process stops automatically. It also prevents new virus particles from forming and reduces the viral load in the body.
Alcohol
consult your doctor
Avoid the consumption of alcohol while taking Sofokast 400mg Tablet as alcohol can reduce the effectiveness of the medicine and worsen the symptoms
Pregnancy
consult your doctor
Do not take the Sofokast 400mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.
Breast Feeding
consult your doctor
Sofokast 400mg Tablet is dangerous to use during breastfeeding as it may cause toxicity to the baby.
Driving
unsafe
Sofokast 400mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Kidney
safe if prescribed
Consumption of Sofokast 400mg Tablet should be avoided without informing the doctor if you have any kidney-related issues.
Liver
safe if prescribed
Consumption of Sofokast 400mg Tablet should be avoided without informing the doctor if you have any liver-related issues.
It is advised not to miss any scheduled dosage of Sofokast 400mg tablet. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
• Go for a liver function test once you start the treatment to ensure normal functioning of the organ.
• Do not share your medicine with other people, as some medicines treat specific genotypes of Hepatitis.
• Some Hepatitis medicines are given in combination with other antiviral drugs. So, it is advised not to use them alone.
• Hepatitis medicines are given to treat HIV/ AIDS patients in some cases. But these medicines are not the proper treatment for this disease.
• It is advised to use effective birth control methods to avoid pregnancy. Some hepatitis drugs can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine.
• It is advised to tell your doctor about all medicines (multivitamins, herbal supplements) you're taking currently before starting your course with hepatitis medicines. There are chances that many drugs can interact, and some drugs should not be used together.
Sofokast is used to treat patients diagnosed with chronic Hepatitis C virus (HCV) infection. This medicine is usually given in combination with other antiviral medicines.
This medicine works by blocking the virus's NS5A protein, which plays an important role in virus replication.
No, it is advised that Sofokast should always be used in combination with other antiviral drugs and not as monotherapy.
A person may experience fatigue, headache, nausea, and insomnia. These side effects are mostly observed when this medicine is given in combination with other antiviral medicines.
It is advised to consult your doctor in this case. As Sofokast may not be safe to take during pregnancy, especially when taken with other antiviral medicines, which can harm the unborn baby.
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1. Asselah, T. (2014). Sofosbuvir for the treatment of hepatitis C virus. Expert opinion on pharmacotherapy, 15(1), 121-130.
2. Keating, G. M., & Vaidya, A. (2014). Sofosbuvir: first global approval. Drugs, 74(2), 273-282.
3. Lawitz, Eric, Alessandra Mangia, David Wyles, Maribel Rodriguez-Torres, Tarek Hassanein, Stuart C. Gordon, Michael Schultz et al. "Sofosbuvir for previously untreated chronic hepatitis C infection." New England Journal of Medicine 368, no. 20 (2013): 1878-1887.
4. Keating, G. M. (2014). Sofosbuvir: a review of its use in patients with chronic hepatitis C. Drugs, 74(10), 1127-1146.
5. Foster, G. R., Afdhal, N., Roberts, S. K., Bräu, N., Gane, E. J., Pianko, S., ... & Sulkowski, M. (2015). Sofosbuvir and velpatasvir for HCV genotype 2 and 3 infection. New England Journal of Medicine, 373(27), 2608-2617.
6. Feld, J. J., Jacobson, I. M., Hézode, C., Asselah, T., Ruane, P. J., Gruener, N., ... & Zeuzem, S. (2015). Sofosbuvir and velpatasvir for HCV genotype 1, 2, 4, 5, and 6 infection. New England Journal of Medicine, 373(27), 2599-2607.
Aprazer Healthcare Pvt Ltd
Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.