Telma ACT 40/5/6.25 mg Tablet

Telma ACT 40/5/6.25mg tablet is an antihypertensive combination medicine. The medicine is used to treat high blood pressure (hypertension) in adults. Its contains three active ingredient is Telmisartan in (40mg) concentration, Amlodipine in (5mg) concentration and Chlorthalidone in (6.25mg) concentration.

They together work to lower the blood pressure effectively, decrease strain on the heart, and lower the risk of cardiovascular complications such as heart attack or stroke. Doctor's prescription is mandatory before using the tablet to avoid complications during the treatment.

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• Treats high blood pressure (Hypertension)
  

Telma ACT 40/5/6.25mg tablet cause several side effects that are easily manageable with certain treatment options. If any of the following symptoms persist or worsen consult the healthcare professional instantly:

• Fatigue (tiredness)
• Bradycardia
• Gastrointestinal disturbance
• Electrolyte imbalance
• The increased glucose level in the blood
• Postural hypotension
• Angioedema and urticaria
• Visual disturbance
• Breathlessness
• Muscle cramp
• Headache
• Dizziness
• Sleepiness
• Ankle swelling​

• Doctor prescription is required while using Telma ACT 40/5/6.25mg tablet to ensure safe and effective treatment option.
• The tablet should be taken with or without food at the same time every day to enhance the effectiveness, maintain consistent blood pressure and reduce the risk of side effects.
• Do not crush, chew or break the tablet as it decrease the effectiveness of the medication and alter its absorption.​
  

• Telma ACT 40/5/6.25mg tablet contains three drugs that lowers blood pressure by Angiotensin-II (constricts vessels), inhibiting calcium entry into muscles (relaxes vessels), and reducing excess fluid/sodium. Telmisartan(40mg) acts as an angiotensin II receptor blocker (ARB) which preventing vasoconstriction and narrowing of blood vessels.
• Amlodipine (5mg) is a calcium channel blocker that prevents calcium from entering vascular smooth muscle cells, causing blood vessels to relax and widen. Chlorthalidone (6.25mg) is a thiazide like diuretic that reducing fluid volume and improving blood flow.​​
  

• McClellan, K. J., & Markham, A. (1998). Telmisartan. Drugs, 56(6). https://pubmed.ncbi.nlm.nih.gov/9878991/
• Sharpe, M., Jarvis, B., & Goa, K. L. (2001). Telmisartan: a review of its use in hypertension. Drugs, 61(10), 1501-1529. https://pubmed.ncbi.nlm.nih.gov/11558835/
• Wang, J. G., Palmer, B. F., Vogel Anderson, K., & Sever, P. (2023). Amlodipine in the current management of hypertension. The Journal of Clinical Hypertension, 25(9), 801-807. https://pubmed.ncbi.nlm.nih.gov/37551050/
• Şen, S., Demir, M., Yiğit, Z., & Üresin, A. Y. (2018). Efficacy and safety of s-amlodipine 2.5 and 5 mg/d in hypertensive patients who were treatment-naive or previously received antihypertensive monotherapy. Journal of Cardiovascular Pharmacology and Therapeutics, 23(4), 318-328. https://pubmed.ncbi.nlm.nih.gov/29649885/
• RAGHAVENDRA, R., Kota, R. K., Setty, C. M., & PURUSHOTHAM, R. (2009). Formulation and evaluation of fast dissolving chlorthalidone tablets. International journal of pharmacy and pharmaceutical sciences, 1(1), 79-87. https://www.researchgate.net/publication/288455994_Formulation_and_evaluation_of_fast_dissolving_chlorthalidone_tablets​