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TENVIR EM

Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)

Tenvir EM

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Tenvir EM 
Generic Name: Emtricitabine and Tenofovir Disoproxil Fumarate
Manufacturer: Cipla 
Dosage Form: Tablet 
Strength:200mg/300mg
Composition: Emtricitabine (200mg) and Tenofovir Disoproxil Fumarate (300mg)
Indication: HIV 
Storage: Store at room temperature 

Overview 

Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate) tablet is an antiretroviral medication. It is used for the treatment of infection caused by HIV (human immunodeficiency virus). This medication helps to delay the production of HIV infection and improves the quality of life. Tenvir EM tablet boost your immune system to fight against infection and prevents the virus from multiplying. It increases the CD4 cell (white blood cells that protect against infection) count in your blood. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately. 

Pharmacodynamics

Emtricitabine (Tenvir EM):- a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. It inhibits the activity of the HIV-1 reverse transcriptase (RT) by competing with the natural substrate deoxycytidine 5'-triphosphate and by being incorporated into nascent viral DNA which results in chain termination. Emtricitabine is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma. 

Tenofovir Disoproxil Fumarate (Tenvir EM):- Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. Tenofovir disoproxil fumarate requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir disoproxil fumarate inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. It is a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma. 

Usage 

Tenvir EM  tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. It is important to take Tenvir EM tablet as prescribed by your doctor. It is advised not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Tenvir EM medicine is decided by a doctor according to your previous medical condition and response to the treatment.

Interactions 

Tenvir EM tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions

  • Leflunomide 

  • Cisplatin 

  • Tobramycin 

  • Gentamicin 

  • Methotrexate

  • Efavirenz 

Disease Interactions 

  • Renal dysfunction 

  • Hepatic Impairment 

Alcohol Interaction

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication

  • Do not take this medicine if you are allergic to Emtricitabine and Tenofovir disoproxil fumarate. 

  • Tenvir EM tablet is not recommended in patients known to be hypersensitive.

  • This medicine is not recommended for use in patients with severe kidney disease. 

Substitutes

  • Emfovir
  • Tenof EM 

  • Ricovir EM 

  • Tofocom

  • Tavin EM 

Side effects 

This medicine may cause some common side effects. Discuss the risks and benefits of the Tenvir EM tablets with the doctor before starting the treatment.

Common side effects

  • Trouble sleeping 

  • Loss of strength 

  • Fatigue 

  • Sore throat 

  • Swollen lymph nodes

  • Loss of appetite 

  • Seizures 

  • Cough 

  • Unusual weakness 

  • Blurred vision 

  • Loss of weight

  • Nausea

  • Insomnia

  • Diarrhea

  • Blood in urine

  • Irregular heartbeat

  • Abnormal dream 

  • Confusion 

  • Indigestion 

  • Constipation

  • Redness of skin

  • Taste changes 

  • Unusual tiredness 

  • Fever 

  • Chills 

Note - immediately contact your health care provider if any side effects occur.

 

Dosage 

Take this medicine as prescribed by your doctor. Make sure to not skip or stop your regular dosing schedule. 

Missed dose 

  • It is advisable not to miss a dose. If you miss a scheduled dose of Tenvir EM tablets, contact your doctor immediately. 

Overdose 

  • In case of an overdose of Tenvir EM tablets, the doctor will provide emergency medical treatment.

Warning

Before starting treatment with Tenvir EM medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use suitable methods of contraception to prevent pregnancy while taking Tenvir EM medicine. 

  • Children and adolescents 

    • Tenvir EM tablets are not recommended for use in children under the age of 12. 

Warnings for female 

  • Pregnancy

    • Do not use Tenvir EM medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy. 

  • Breastfeeding

    • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate).

Precautions 

  • Tenvir EM increases the risk of lactic acidosis.

  • Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, abnormal dream, anxiety, etc.

  • This medication may increase the risk of immune reconstitution syndrome. 

  • Close monitoring of bone mineral density is required during treatment with this medicine.

  • Tenvir EM tablet is not recommended for use in patients requiring hemodialysis. 

Cautions 

  • Do not drive or operate heavy machinery.

  • Do not crush or break the tablet. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication.

Q1. What is Tenvir EM (Emtricitabine and Tenofovir disoproxil fumarate)?

Ans. Tenvir EM tablet is an antiviral medication that prevents the human immunodeficiency virus (HIV) from multiplying in your body. It also helps to delay the production of HIV infection and improves the quality of life. 

Q2. How does Tenvir EM work?

Ans. This medication helps to boost your immune system to fight against infection and also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Q3. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q4. What should I avoid while receiving this medication? 

Ans. Follow your doctor’s advice about any restrictions on food and other activities.

Q5. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of Trustiva tablets, contact your doctor immediately.

Q6.  What are the side effects?

Ans. Some common side effects are:- fatigue, sore throat, headache, nausea, taste change, stomach ache, peripheral neuropathy, diarrhea, fever, chills, blurred vision, weight loss, abnormal dreams, etc.

Q7. In what strength is it available? 

Ans. It is available in the strength of 200mg/300mg.

Q8.  Can I drive after taking this medicine? 

Ans. Tenvir EM tablet may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur. 

Q9. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended during pregnancy.

Q10. What are the self-care tips? 

Ans. Maintain good nutrition and keep yourself hydrated.

Q11. What are the storage conditions?

Ans. Store this medicine at room temperature. Keep it away from direct heat and light. 

Q12. Does this medicine affect liver function? 

Ans. Please consult your doctor before consuming this drug.

Q13.  How to take this medicine?

Ans. It is important to take this medicine as prescribed by your doctor. 

 

Above Content has been reviewed by Professionals