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TENVIR 300MG TABLET

Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)

Tenvir 300mg Tablet

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Tenvir 
Generic Name: Tenofovir Disoproxil Fumarate
Manufacturer: Cipla 
Dosage Form: Tablet 
Strength: 300mg
Composition: Tenofovir Disoproxil Fumarate
Indication: HIV 
Storage: Store at room temperature 

Overview

Tenvir 300mg (Tenofovir Disoproxil Fumarate) tablet is used in the treatment of HIV (Human immunodeficiency virus) infection. This medication helps to reduce the amount of HIV in your body and improves the quality of life. It boosts your immune system to fight against infection and prevents the virus from multiplying. It increases the CD4 cell (white blood cells that protect against infection) count in your blood. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. 

Pharmacodynamics 

Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. It requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir diphosphate works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. It is a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma. 

Usage 

Tenvir 300mg tablet contains Dolutegravir as an active ingredient. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. The recommended dose of Tenvir medicine is decided by a doctor according to your previous medical condition and response to the treatment. It is important to take this medicine as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Tenvir medicine is decided by a doctor according to your previous medical condition and response to the treatment.

 

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Side Effect of Tenvir 300mg Tablet

This medicine may cause some common side effects. Discuss the risks and benefits of the Tenvir tablets with the doctor before starting the treatment.

Common side effects

  • Trouble sleeping 

  • Loss of strength 

  • Fatigue 

  • Sore throat 

  • Swollen lymph nodes

  • Loss of appetite 

  • Seizures 

  • Cough 

  • Unusual weakness 

  • Blurred vision 

  • Loss of weight

  • Nausea

  • Insomnia

  • Diarrhea

  • Blood in urine

  • Irregular heartbeat

  • Abnormal dream 

  • Confusion 

  • Indigestion 

  • Constipation

  • Redness of skin

  • Taste changes 

  • Unusual tiredness 

  • Fever 

  • Chills 

Note - immediately contact your health care provider if any side effects occur.

Dosage 

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule. 

Missed dose 

  • It is advisable not to miss a dose. If you miss a scheduled dose of Tenvir tablets, contact your doctor immediately. 

Overdose 

  • In case of an overdose of Tenvir tablets, the doctor will provide emergency medical treatment.

Warning

Before starting treatment with Tenvir medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use suitable methods of contraception to prevent pregnancy while taking Tenvir medicine. 

  • Children and adolescents 

    • Tenvir tablets are not recommended for use in children under the age of 18. 

Warnings for female 

  • Pregnancy

    • Do not use Tenvir medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy. 

  • Breastfeeding

    • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Tenvir (Tenofovir Disoproxil Fumarate).

Precautions

  • Tenvir increases the risk of lactic acidosis.

  • Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, abnormal dream, anxiety, etc.

  • This medication may increase the risk of immune reconstitution syndrome. 

  • Close monitoring of bone mineral density is required during treatment with this medicine.

Cautions 

  • Do not drive or operate heavy machinery.

  • Do not crush or break the tablet. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication.

Q1. What is Tenvir 300mg Tablet (Tenofovir disoproxil fumarate)?

Ans. Tenvir tablet is an antiviral medication that prevents the human immunodeficiency virus (HIV) from multiplying in your body. It also helps to delay the production of HIV infection and improves the quality of life. 

Q2. How does Tenvir 300mg Tablet work?

Ans. This medication helps to boost your immune system to fight against infection and also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Q3. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q4. What should I avoid while receiving this medication? 

Ans. Follow your doctor’s advice about any restrictions on food and other activities.

Q5. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of Trustiva tablets, contact your doctor immediately.

Q6.  What are the side effects?

Ans. Some common side effects are:- fatigue, sore throat, headache, nausea, taste change, stomach ache, peripheral neuropathy, diarrhea, fever, chills, blurred vision, weight loss, abnormal dreams, etc.

Q7. In what strength is it available? 

Ans. It is available in the strength of 300mg.

Q8.  Can I drive after taking this medicine? 

Ans. This medicine may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur. 

Q9. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended during pregnancy.

Q10. What are the self-care tips? 

Ans. Maintain good nutrition and keep yourself hydrated.

Q11. What are the storage conditions?

Ans. Store this medicine at room temperature. Keep it away from direct heat and light. 

Q12. Does this medicine affect liver function? 

Ans. Please consult your doctor before consuming this drug.

Q13.  How to take this medicine?

Ans. It is important to take this medicine as prescribed by your doctor. 

Interactions 

Tenvir 300mg tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions 

  • Cisplatin 

  • Tobramycin 

  • Gentamicin 

  • Darunavir 

Disease Interactions

  • Renal dysfunction 

  • Hepatic Impairment 

Alcohol Interaction

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication

  • Do not take this medicine if you are allergic to Tenofovir disoproxil fumarate. 

  • Tenvir 300mg tablet is not recommended in patients known to be hypersensitive.

Reference

  • Tenofovir Disoproxil fumarate: Drug information available at: https://clinicalinfo.hiv.gov/en/drugs/tenofovir-disoproxil-fumarate/patient and https://medlineplus.gov/druginfo/meds/a602018.html.

Tenofovir Disoproxil fumarate: Drug Uses, mechanism, and Side Effects available at: https://www.drugs.com/mtm/tenofovir.html and https://www.webmd.com/drugs/2/drug-22107-6330/tenofovir-disoproxil-fumarate-oral/tenofovir-oral/details.

Above Content has been reviewed by Professionals