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TOFACITINIB 5MG TABLET (TOFAJAK) UP TO 22% OFF

Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)

Tofacitinib 5mg Tablet (Tofajak) UP To 22% Off

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Medicine details 

Brand name

Tofajak

Generic Name

Tofacitinib

Strength

5mg

Manufacturer

Cipla

Dosage form

Tablet

Indication

Rheumatoid arthritis

Storage

Store at room temperature

Overview

Tofajak tablets is a prescription regimen comprising tofacitinib 5mg. It is used in the treatment of patients suffering from severely active rheumatoid arthritis and psoriatic arthritis. This medication works by reducing the signs and symptoms of arthritis in patients who have shown no response to methotrexate. It helps to decrease the swelling in adult patients (over the age of 18 years). Tofajak is also used to treat patients with ulcerative colitis. Tofajak (Tofacitinib) is available in the form of oral-use tablets in the strength of 5mg. 

Pharmacodynamics

tofacitinib 5mg, the active ingredient of Tofajak tablets, is a partial and reversible Janus kinase (JAK) inhibitor that works to prevent the body from responding to cytokine signals. By inhibiting JAKs, this compound actively hinders the phosphorylation and activation of STATs. The JAK-STAT signaling pathway is involved in the transcription of cells that are involved in hematopoiesis, and immune cell function. Tofajak tablet works therapeutically by causing inhibition against the JAK-STAT pathway to reduce the inflammatory response in the body. However, there is evidence to suggest that it may also achieve efficacy through other pathways also.

Medicine Interactions 

·         Phenobarbital

·         Adalimumab

·         Clozapine

·         Live attenuated vaccines and related products

Disease Interactions 

·         Hyperlipidemia

·         Infections

·         Tuberculosis

·         Hepatic impairment

·         Hepatitis B

Alcohol Interactions 

·         Interactions between the ingredients of Tofajak tablets and alcohol are not known. Please check with your doctor before consuming alcohol. 

Contraindications

Tofajak (tofacitinib 5mg) tablets are contraindicated in the following cases:- 

·         Hypersensitivity 

·         Allergy to Tofacitinib

·         Allergy to inactive ingredients of the tablets

·         Patients aged below 18  

Alternative

Xeljanz

Side effects of tofacitinib 5mg tablet

Tofajak (tofacitinib 5mg) tablets may cause side effects when administered to the patients. The following is a list of the same. 

  • Diarrhea 
  • Headache
  • Dizziness
  • Drowsiness 
  • Cough 
  • Trouble breathing 
  • Night sweats 
  • Sore throat 
  • Fever 
  • Chills 
  • Stomach pain 
  • Nausea 
  • Vomiting 
  • Itching 
  • Night sweats 
  • Dark urine 
  • Frequent urination
  • Redness on skin
  • Swelling on feet
  • Unusual tiredness 
  • Fatigue 
  • Body ache 
  • Weight gain 
  • Itching 
  • Irritation
  • Yellowing of the skin
  • Pale eyes 

Note:- Be sure to seek help from a medical practitioner if the condition worsens due to the side effects.

Dosage

The dose of Tofajak (tofacitinib 5mg) tablets is recommended by the healthcare professional as per the patient’s health and requirements. These tablets are indicated for oral use. Swallow the tablets as a whole with water. 

Missed dose

If you miss a dose of Tofajak (tofacitinib 5mg) tablets, make sure to call your healthcare professional to know the ways of managing the missed dose. Ask your doctor for methods of coping. 

Overdose

If symptoms of overdose occur, it becomes important to contact the nearest medical professional immediately for supportive care. Kindly do not ignore any symptoms. 

Warnings for Female

  • Pregnancy 
    • Tofajak (tofacitinib 5mg) tablets are not recommended unless necessary in women who are pregnant or plan to get pregnant. Consult a medical professional. 
  • Breastfeeding 
    • Tofajak (tofacitinib 5mg) tablets are not recommended unless necessary in women who are breastfeeding or plan to feed a child. Consult a medical professional.

Precautions 

  • Contraception 
    •  
  • Children and adolescents 
    • The safety and efficacy of Tofajak (Tofacitinib) tablets have not been established. Therefore, this medication is not indicated for use in patients below the age of 18 years.

Cautions

  • Do not crush or bite Tofajak (Tofacitinib) tablets,
  • Do not operate any machinery that requires concentration after taking Tofajak (Tofacitinib) tablets. 
  • Do not administer Tofajak (Tofacitinib) tablets in greater quantities. 
  • Do not store Tofajak (Tofacitinib) tablets in extreme temperatures. 

Q1. What is Tofajak (tofacitinib 5mg tablet)?

Ans. Tofajak tablets is a prescription regimen comprising Tofacitinib. It is used in the treatment of patients suffering from severely active rheumatoid arthritis and psoriatic arthritis.

Q2. How to use Tofajak (tofacitinib 5mg tablet)?

Ans. The dose of Tofajak (tofacitinib 5mg) tablets is recommended by the healthcare professional as per the patient’s health and requirements. These tablets are indicated for oral use. Swallow the tablets as a whole with water. 

Q3. Does Tofajak (tofacitinib 5mg tablet) cause any side effects?

Ans. Tofajak (tofacitinib 5mg) tablets can cause certain side effects like headache, fever, chills, skin rash, dizziness, drowsiness, loss of appetite, etc. 

Q4. What happens if I overdose on Tofajak (tofacitinib 5mg tablet)?

Ans. If symptoms of overdose occur, it becomes important to contact the nearest medical professional immediately for supportive care. Kindly do not ignore any symptoms. 

Q5. Is it safe to use Tofajak (tofacitinib 5mg tablet) during pregnancy?

Ans. Tofajak 5mg (Tofacitinib) tablets are not recommended unless necessary in women who are pregnant or plan to get pregnant. Consult a medical professional. 

Q6. Does Tofajak (tofacitinib 5mg tablet) affect kidney function?

Ans. Tofajak (Tofacitinib) tablets may affect the patients who are already suffering from any kidney disease. It is important to consult a doctor regarding the same. 

Q7. Can I drink alcohol after taking Tofajak (tofacitinib tablet)?

Ans. Interactions between the ingredients of Tofajak tablets and alcohol are not known. Please check with your doctor before consuming alcohol. 

Q8. In what strength is Tofajak (tofacitinib tablet) available?

Ans. Tofajak (tofacitinib tablet) is available in the form of oral-use tablets in the strength of 5mg by Cipla. 

Q9. Is it safe to use Tofajak (tofacitinib 5mg tablet) during breastfeeding?

Ans. Tofajak (Tofacitinib) tablets are not recommended unless necessary in women who are breastfeeding or plan to feed a child. Consult a medical professional.

Q10. What are the storage conditions of Tofajak (tofacitinib 5mg tablet)?

Ans. Store Tofajak (tofacitinib 5mg) tablets at room temperature. Protect from light, heat, and moisture.

Reference

Tofacitinib: Drugs information and usage are available at: - https://go.drugbank.com/drugs/DB08895 and https://www.drugs.com/tofacitinib.html.

Tofacitinib: Mechanism, side effects, and dosage are available at: - https://www.webmd.com/drugs/2/drug-162858-1509/tofacitinib-oral/tofacitinib-oral/details, https://medlineplus.gov/druginfo/meds/a613025.html, and https://www.drugs.com/tofacitinib.html.

Above Content has been reviewed by Professionals