Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
|
Brand name |
Tofajak |
|
Generic Name |
Tofacitinib |
|
Strength |
5mg |
|
Manufacturer |
Cipla |
|
Dosage form |
Tablet |
|
Indication |
Rheumatoid arthritis |
|
Storage |
Store at room temperature |
Tofajak tablets is a prescription regimen comprising tofacitinib 5mg. It is used in the treatment of patients suffering from severely active rheumatoid arthritis and psoriatic arthritis. This medication works by reducing the signs and symptoms of arthritis in patients who have shown no response to methotrexate. It helps to decrease the swelling in adult patients (over the age of 18 years). Tofajak is also used to treat patients with ulcerative colitis. Tofajak (Tofacitinib) is available in the form of oral-use tablets in the strength of 5mg.
tofacitinib 5mg, the active ingredient of Tofajak tablets, is a partial and reversible Janus kinase (JAK) inhibitor that works to prevent the body from responding to cytokine signals. By inhibiting JAKs, this compound actively hinders the phosphorylation and activation of STATs. The JAK-STAT signaling pathway is involved in the transcription of cells that are involved in hematopoiesis, and immune cell function. Tofajak tablet works therapeutically by causing inhibition against the JAK-STAT pathway to reduce the inflammatory response in the body. However, there is evidence to suggest that it may also achieve efficacy through other pathways also.
· Phenobarbital
· Adalimumab
· Clozapine
· Live attenuated vaccines and related products
· Hyperlipidemia
· Infections
· Tuberculosis
· Hepatic impairment
· Hepatitis B
· Interactions between the ingredients of Tofajak tablets and alcohol are not known. Please check with your doctor before consuming alcohol.
Tofajak (tofacitinib 5mg) tablets are contraindicated in the following cases:-
· Hypersensitivity
· Allergy to Tofacitinib
· Allergy to inactive ingredients of the tablets
· Patients aged below 18
Tofajak (tofacitinib 5mg) tablets may cause side effects when administered to the patients. The following is a list of the same.
Note:- Be sure to seek help from a medical practitioner if the condition worsens due to the side effects.
The dose of Tofajak (tofacitinib 5mg) tablets is recommended by the healthcare professional as per the patient’s health and requirements. These tablets are indicated for oral use. Swallow the tablets as a whole with water.
If you miss a dose of Tofajak (tofacitinib 5mg) tablets, make sure to call your healthcare professional to know the ways of managing the missed dose. Ask your doctor for methods of coping.
If symptoms of overdose occur, it becomes important to contact the nearest medical professional immediately for supportive care. Kindly do not ignore any symptoms.
Ans. Tofajak tablets is a prescription regimen comprising Tofacitinib. It is used in the treatment of patients suffering from severely active rheumatoid arthritis and psoriatic arthritis.
Ans. The dose of Tofajak (tofacitinib 5mg) tablets is recommended by the healthcare professional as per the patient’s health and requirements. These tablets are indicated for oral use. Swallow the tablets as a whole with water.
Ans. Tofajak (tofacitinib 5mg) tablets can cause certain side effects like headache, fever, chills, skin rash, dizziness, drowsiness, loss of appetite, etc.
Ans. If symptoms of overdose occur, it becomes important to contact the nearest medical professional immediately for supportive care. Kindly do not ignore any symptoms.
Ans. Tofajak 5mg (Tofacitinib) tablets are not recommended unless necessary in women who are pregnant or plan to get pregnant. Consult a medical professional.
Ans. Tofajak (Tofacitinib) tablets may affect the patients who are already suffering from any kidney disease. It is important to consult a doctor regarding the same.
Ans. Interactions between the ingredients of Tofajak tablets and alcohol are not known. Please check with your doctor before consuming alcohol.
Ans. Tofajak (tofacitinib tablet) is available in the form of oral-use tablets in the strength of 5mg by Cipla.
Ans. Tofajak (Tofacitinib) tablets are not recommended unless necessary in women who are breastfeeding or plan to feed a child. Consult a medical professional.
Ans. Store Tofajak (tofacitinib 5mg) tablets at room temperature. Protect from light, heat, and moisture.
Reference
Tofacitinib: Drugs information and usage are available at: - https://go.drugbank.com/drugs/DB08895 and https://www.drugs.com/tofacitinib.html.
Tofacitinib: Mechanism, side effects, and dosage are available at: - https://www.webmd.com/drugs/2/drug-162858-1509/tofacitinib-oral/tofacitinib-oral/details, https://medlineplus.gov/druginfo/meds/a613025.html, and https://www.drugs.com/tofacitinib.html.
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