Can Trombonat 50mg Tablet be given with other medication?

Yes, Trombonat 50mg Tablet can be given in combination with other medicine based on doctor's assessment about your disease and its stage. Consult the doctor about drug interaction.

What if I miss the dose of Trombonat 50mg Tablet?

Take the Trombonat 50mg Tablet as soon as you remember it unless it’s near the time of next dose. Avoid over dosage of medicine as it can cause harm to the body.

How long is the treatment duration with Trombonat 50mg Tablet medication?

Trombonat 50mg Tablet medication course usually varies, depending on the multiple factors such as patient's overall health, disease etc.

Does Trombonat 50mg Tablet effect the kidney and Liver of the body?

Yes, Trombonat 50mg Tablet negatively affect the kidney as well as liver of the body to a great extent if not monitored timely.

Buy Trombonat 50mg Tablet Online: Price, Uses, and Side Effects

Name: Trombonat 50mg Tablet
Brand: Trombonat
Price: 2500 INR
Availability: InStock
Rating: 4.71 (7 reviews)

Description

Trombonat 50mg Tablet is prescribed by the doctor to treat low platelet counts in specific blood-related conditions. It is mainly given in combination with other medicines to treat a particular condition or increase effectiveness.

Trombonat 50mg Tablet contains Eltrombopag that promotes the proliferation and differentiation of megakaryocytes, leading to increased platelet formation and reduced bleeding risk in conditions like chronic ITP, hepatitis C-related thrombocytopenia, or severe aplastic anemia. Take it exactly as prescribed by the doctor.

Uses

Chronic idiopathic thrombocytopenia
Severe Aplastic Anemia
Low platelet count due to ITP or HCV infection

Side Effects

Trombonat 50mg can cause multiple side effects, most of which are mild to moderate and often temporary. Patients are advised to inform their healthcare provider immediately if symptoms stays for prolonged period of time.

Headache
Nausea
Tiredness
Diarrhea
Insomnia
Dizziness
Loss of Appetite
Rashes
Muscle Pain
Fever
Chills
Allergic Reaction
Liver Problem
Blood Clots
Allergic Reaction

How To Use

The usual dose of Trombonat 50mg is one tablet daily. It should be taken on an empty stomach, at the same time each day for consistent blood levels. Consult your doctor for individual dosage as it may vary person to person based on its stage and overall health.
Tablet is taken orally with the help of water. Avoid breaking, chewing, biting and crushing of tablet to maintain the medication efficacy.

How It Works

Trombonat 50mg Tablet contains Eltrombopag, Eltrombopag binds to and activates the trans-membrane domain of the TPO receptor (c-Mpl) on megakaryocyte progenitors in the bone marrow, triggering signaling pathways.
This promotes the proliferation and differentiation of megakaryocytes, leading to increased platelet formation and reduced bleeding risk in conditions like chronic ITP, hepatitis C-related thrombocytopenia, or severe aplastic anemia.

Safety Advice

Alcohol

Avoid the consumption of alcohol while taking Trombonat 50mg Tablet, as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms.

Pregnancy

Do not take Trombonat 50mg Tablet without consulting the doctor in case of pregnancy, as it can be unsafe to take it during this period.

Breast Feeding

Breastfeeding women should discuss the potential risks and benefits of the Trombonat 50mg Tablet with their healthcare provider before starting treatment.

Driving

Trombonat 50mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.

Kidney

Share your medical history with the doctor before starting the Trombonat 50mg Tablet. Do not take it without consulting a doctor if you have any kidney related issue.

Liver

Share your medical history with the doctor before starting the Trombonat 50mg Tablet. Do not take it without consulting a doctor if you have any liver related issue.

FAQs

Trombonat 50mg Tablet is used to treat low platelet counts in specific blood-related conditions.

References

Elgebaly, A. S., Ashal, G. E., Elfil, M., & Menshawy, A. (2017). Tolerability and efficacy of eltrombopag in chronic immune thrombocytopenia: meta-analysis of randomized controlled trials. Clinical and Applied Thrombosis/Hemostasis, 23(8), 928-937. https://pubmed.ncbi.nlm.nih.gov/27572890/
Wong, R. S., Saleh, M. N., Khelif, A., Salama, A., Portella, M. S. O., Burgess, P., & Bussel, J. B. (2017). Safety and efficacy of long-term treatment of chronic/persistent ITP with eltrombopag: final results of the EXTEND study. Blood, The Journal of the American Society of Hematology, 130(23), 2527-2536. https://pubmed.ncbi.nlm.nih.gov/29042367/
Bussel, J. B., Cheng, G., Saleh, M. N., Psaila, B., Kovaleva, L., Meddeb, B., ... & Jenkins, J. M. (2007). Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. New England Journal of Medicine, 357(22), 2237-2247. https://pubmed.ncbi.nlm.nih.gov/18046028/
Saleh, M. N., Bussel, J. B., Cheng, G., Meyer, O., Bailey, C. K., Arning, M., & Brainsky, A. (2013). Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label EXTEND study. Blood, The Journal of the American Society of Hematology, 121(3), 537-545. https://pubmed.ncbi.nlm.nih.gov/23169778/
Cheng, G., Saleh, M. N., Marcher, C., Vasey, S., Mayer, B., Aivado, M., ... & Bussel, J. B. (2011). Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study. The Lancet, 377(9763), 393-402. https://pubmed.ncbi.nlm.nih.gov/20739054/
Bussel, J. B., de Miguel, P. G., Despotovic, J. M., Grainger, J. D., Sevilla, J., Blanchette, V. S., ... & Bakshi, K. K. (2015). Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study. The Lancet Haematology, 2(8), e315-e325. https://pubmed.ncbi.nlm.nih.gov/26688484/

Trombonat 50mg Tablet

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