Brand Name: Tykerb
Generic Name: Lapatinib
Dosage Form: Tablet
Indication: Breast cancer
Packaging: 30 tablets
Storage: Store at room temperature
Tykerb (Lapatinib 250mg tablet) is used in the treatment of Breast cancer. It belongs to a class of medications known as antineoplastics. This medicine works by slowing or stopping the growth of cancer cells. It is important to take this medicine as prescribed by your doctor. The recommended dose of Tykerb tablet is decided by a doctor according to your previous medical condition and response to the treatment. Do not stop the use of (Lapatinib 250mg tablets without consulting with your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.
Pharmacodynamics of Lapatinib 250mg tablet
Lapatinib is a small molecule and a member of the 4-anilinoquinazoline class of kinase inhibitors. It retained significant activity against breast cancer cell lines selected for long-term growth in the trastuzumab-containing medium in vitro. These in vitro findings suggest non–cross-resistance between these two agents. Hormone receptor-positive breast cancer cells (with ER [Estrogen Receptor] and PgR [Progesterone Receptor]) that coexpress the HER2 tend to be resistant to established endocrine therapies. Similarly, hormone receptor-positive breast cancer cells that initially lack EGFR or HER2 upregulate these receptor proteins as the tumor becomes resistant to endocrine therapy.
Usage of Lapatinib 250mg tablet
Tykerb is an anti-cancer medication that is also used in the treatment of a certain type of Breast cancer (HER2-positive). Take this medicine on an empty stomach one hour before or two hours after the meals. Tykerb tablet works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor.
Side effects of Lapatinib 250mg Tablet
This medicine may cause some common side effects. Discuss the risks and benefits of the Tykerb tablets with the doctor before starting the treatment.
Common side effects
Loss of appetite
Loss of strength
Note - Please consult your medical practitioner if any side effects occur.
Dosage of Lapatinib 250mg tablet
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
Before starting treatment with Tykerb medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Warnings for female
Close monitoring of cardiac dysfunction is required while having treatment with Lapatinib 250mg tablet.
This medicine should be used with caution in patients who have proloa ngation of QT interval.
Inform your doctor if you experience any side effects like - dizziness, nausea, abdominal pain, loss of appetite, irregular heartbeat, and vomiting.
Regular monitoring of platelet count is required during treatment with this medicine.
Tykerb medicine may cause severe diarrhea in some patients.
Do not drive or operate heavy machinery.
Do not crush or break the tablet.
Not safe for pregnant women.
Q1. What is Tykerb (Lapatinib 250mg Tablet)?
Ans. It is an anti-cancer medication that is used in the treatment of a certain type of Breast cancer (HER2-positive).
Q2. What are the side effects of Lapatinib 250mg tablet?
Ans. Some common side effects of Lapatinib 250mg tablet are - joint pain, pale skin, dehydration, indigestion, constipation, headache, etc.
Q3. In what strength is it available?
Ans. This medicine is available in the strength of 250mg.
Q4. Can I consume alcohol while receiving this medicine?
Ans. Please consult your doctor before consuming alcohol.
Q5. What happens if I miss a dose?
Ans. If you miss a scheduled dose of Tykerb tablets, contact your doctor immediately.
Q6. How to take this medicine?
Ans. It is important to take this medicine as prescribed by your doctor.
Q7. Can I drive after taking this medicine?
Ans. This medicine may affect your vision and your ability to concentrate.
Q8. How does Tykerb tablet work?
Ans. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This helps to stop the growth of cancer cells.
Q9. Can I take Lapatinib 250mg tablet during pregnancy?
Ans. This medicine is not recommended during pregnancy.
Q10. What should I avoid while receiving Lapatinib 250mg tablet?
Ans. Follow your doctor’s advice about any restrictions on food and other activities.
Q11. Can I take Lapatinib 250mg tablet during breastfeeding?
Ans. This medicine is not recommended for breastfeeding unless it is necessary.
Q12. Does this medicine affect liver function?
Ans. Please consult your doctor before consuming this drug.
Q13. What are the storage conditions?
Ans. Store this medicine at room temperature.
Tykerb tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
- Cardiac dysfunction
- Liver impairment
- Pulmonary toxicity
- Lung impairment
- Dermatologic toxicities
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
- Do not take this medicine if you are allergic to Lapatinib.
- Tykerb (Lapatinib) medicine is not recommended in patients known to be hypersensitive.
Lapatinib: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a607055.html
Lapatinib: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB01259