Mfd. by :- Glaxo SmithKline Pharmaceuticals (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name: Tykerb
Generic Name: Lapatinib
Manufacturer: GlaxoSmithKline
Dosage Form: Tablet
Strength: 250mg
Composition: Lapatinib
Indication: Breast cancer
Packaging: 30 tablets
Storage: Store at room temperature
Tykerb (Lapatinib 250mg tablet) is used in the treatment of Breast cancer. It belongs to a class of medications known as antineoplastics. This medicine works by slowing or stopping the growth of cancer cells. It is important to take this medicine as prescribed by your doctor. The recommended dose of Tykerb tablet is decided by a doctor according to your previous medical condition and response to the treatment. Do not stop the use of (Lapatinib 250mg tablets without consulting with your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.
Lapatinib is a small molecule and a member of the 4-anilinoquinazoline class of kinase inhibitors. It retained significant activity against breast cancer cell lines selected for long-term growth in the trastuzumab-containing medium in vitro. These in vitro findings suggest non–cross-resistance between these two agents. Hormone receptor-positive breast cancer cells (with ER [Estrogen Receptor] and PgR [Progesterone Receptor]) that coexpress the HER2 tend to be resistant to established endocrine therapies. Similarly, hormone receptor-positive breast cancer cells that initially lack EGFR or HER2 upregulate these receptor proteins as the tumor becomes resistant to endocrine therapy.
Tykerb is an anti-cancer medication that is also used in the treatment of a certain type of Breast cancer (HER2-positive). Take this medicine on an empty stomach one hour before or two hours after the meals. Tykerb tablet works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor.
This medicine may cause some common side effects. Discuss the risks and benefits of the Tykerb tablets with the doctor before starting the treatment.
Joint pain
Irregular heartbeat
Pale skin
Headache
Abdominal pain
Severe diarrhea
Fatigue
Nausea
Constipation
Stomatitis
Weight gain
Loss of appetite
Rash
Insomnia
Liver damage
Vomiting
Breathing problems
Cough
Increased bilirubin in the blood
Mucosal inflammation
Back pain
Dizziness
Sore throat
Heartburn
Loss of strength
Indigestion
Blistering
Fainting
Chest pain
Nose bleeds
Dehydration
Note - Please consult your medical practitioner if any side effects occur.
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
It is advisable not to miss a dose. If you miss a scheduled dose of Tykerb tablets, contact your doctor immediately.
In case of an overdose of Tykerb tablets, the doctor will provide emergency medical treatment.
Before starting treatment with Tykerb medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Contraception
Use suitable methods of contraception to prevent pregnancy while taking this medicine.
Pregnancy
Do not use Tykerb medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
Breastfeeding
Lapatinib 250mg tablet is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with this medication.
Close monitoring of cardiac dysfunction is required while having treatment with Lapatinib 250mg tablet.
This medicine should be used with caution in patients who have proloa ngation of QT interval.
Inform your doctor if you experience any side effects like - dizziness, nausea, abdominal pain, loss of appetite, irregular heartbeat, and vomiting.
Regular monitoring of platelet count is required during treatment with this medicine.
Tykerb medicine may cause severe diarrhea in some patients.
Close monitoring of liver and kidney function is required while receiving treatment with this medicine.
Do not drive or operate heavy machinery.
Do not crush or break the tablet.
Not safe for pregnant women.
Do not breastfeed while receiving this medication.
Ans. It is an anti-cancer medication that is used in the treatment of a certain type of Breast cancer (HER2-positive).
Ans. Some common side effects of Lapatinib 250mg tablet are - joint pain, pale skin, dehydration, indigestion, constipation, headache, etc.
Ans. This medicine is available in the strength of 250mg.
Ans. Please consult your doctor before consuming alcohol.
Ans. If you miss a scheduled dose of Tykerb tablets, contact your doctor immediately.
Ans. It is important to take this medicine as prescribed by your doctor.
Ans. This medicine may affect your vision and your ability to concentrate.
Ans. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This helps to stop the growth of cancer cells.
Ans. This medicine is not recommended during pregnancy.
Ans. Follow your doctor’s advice about any restrictions on food and other activities.
Ans. This medicine is not recommended for breastfeeding unless it is necessary.
Ans. Please consult your doctor before consuming this drug.
Ans. Store this medicine at room temperature.
Tykerb tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
Alcohol Interaction
Reference
Lapatinib: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a607055.html
Lapatinib: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB01259
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