Mfd. by :- Abbott (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand name - Viroclear
Generic name - Sofosbuvir
Type - Allopathic
Manufacturer - Abbott
Salt composition - Sofosbuvir 400mg
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (tablet)
Strength - 400mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Prescription required - Yes
Indication - Chronic hepatitis C virus (HCV) infection
Viroclear (Sofosbuvir) 400mg is an antiviral medicine. This medication is used in the treatment of chronic (long-lasting) Hepatitis C Virus infection, along with other medications. Viroclear works to lower the multiplication of viruses (HCV) in the body.
Sofosbuvir inhibits the Hepatitis C NS5B protein. Sofosbuvir has a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, where the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half life of Sofosbuvir is 0.4 hours, and the half life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.
The active ingredient of Viroclear is Sofosbuvir 400mg.
Viroclear tablet (400mg) is used to treat chronic Hepatitis C Virus infection in adults. It works to lower the multiplication of HCV in the body.
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Take Viroclear 400mg exactly as your healthcare provider tells you.
In case of a missed dose, take the dose as soon as you remember. However, if it is already the time for the next scheduled dose, do not take the missed dose. Do not double the dose to catch up.
In case of overdose, seek emergency medical attention.
Make sure to tell your healthcare provider about your medical history and the medicines you already take, before consuming Viroclear tablets.
Avoid driving or operating heavy machinery, in case you feel unwell after taking this medicine.
Avoid the consumption of alcohol.
Keep yourself hydrated.
Viroclear 400mg (Sofosbuvir) should be administered with utmost caution in patients with kidney disease.
In patients with liver disease, Viroclear tablets should be given only when prescribed by the healthcare provider.
Tell your healthcare provider about all the side effects you experience (even the minor ones).
Viroclear should be used with caution in patients having a known medical history of Hepatitis B, due to increased risk of adverse reaction.
Viroclear is not recommended for use to the patients having a known allergy to Sofosbuvir or any other ingredient of the medicine.
This medicine is not recommended in patients with a known medical history of Pancreatitis, due to an increased risk of adverse reactions.
A- Viroclear 400mg tablets are used with other medications to treat chronic (long-lasting) Hepatitis C Virus infection in adults.
A- Viroclear (Sofosbuvir) is available in the strength of 400mg.
A- Store at room temperature (10-30°C). Keep it away from children, direct light and moisture.
A- Viroclear can cause side effects such as fever, chills, insomnia, anemia, diarrhea, loss of appetite, nausea and fatigue. Make sure to consult your healthcare provider if you experience these or any other side effects.
A- If you feel unwell (dizzy or tired) after taking Viroclear tablet, do not drive.
A- Please contact your healthcare provider.
A- Viroclear 400mg tablet is safe during breastfeeding, only if prescribed by a professional doctor.
A- Viroclear should be administered with caution in patients with kidney disease. Make sure to ask your healthcare provider before consuming this medicine.
A- Take this medicine with food, at the same time everyday preferably. Ask your healthcare provider about the dose strength.
A- Consult your healthcare provider before taking Viroclear.
A- No, it is not a habit forming medication.
A- Seek emergency medical support in case of overdose.
A- Take the dose as soon as you remember. However, if it is already the time for the next dose, skip the previous dose and take the next scheduled dose. Do not double the dose strength to catch up.
A- If you feel unwell after taking this medicine, avoid driving or operating heavy machinery.
A- Avoid eating sugary foods.
A- Avoid consumption of alcohol with this medication.