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Abbott
28 tablet
Sofosbuvir 400mg
Keep in cold place
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Overview
Viroclear 400mg tablet is an antiviral medicine. This medication is used in the treatment of chronic (long-lasting) Hepatitis C Virus infection, along with other medications. Viroclear works to lower the multiplication of viruses (HCV) in the body.
Hepatitis C
Sofosbuvir inhibits the Hepatitis C NS5B protein. Sofosbuvir has a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, where the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.
Most Viroclear 400mg Tablet side effects do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Fever
Chills
Headache
Tiredness
Unusual dizziness
Nausea
Loss of appetite
Insomnia
Irritability
Diarrhea
Fatigue
Lower back pain
Mouth ulcers
Fainting
Skin rash
Anemia
Take Viroclear 400mg exactly as your healthcare provider tells you.
In case of overdose, seek emergency medical attention.
Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
consult your doctor
Do not take Viroclear 400mg Tablet without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take Viroclear 400mg Tablet without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
In case of a missed dose, take the dose as soon as you remember. However, if it is already time for the next scheduled dose, do not take the missed dose. Do not double the dose to catch up.
Viroclear 400mg tablets are used with other medications to treat chronic (long-lasting) Hepatitis C Virus infection in adults.
Store at room temperature (10-30°C). Keep it away from children, direct light, and moisture.
Viroclear can cause side effects such as fever, chills, insomnia, anemia, diarrhea, loss of appetite, nausea and fatigue. Make sure to consult your healthcare provider if you experience these or any other side effects.
If you feel unwell (dizzy or tired) after taking Viroclear tablet, do not drive.
Viroclear should be administered with caution in patients with kidney disease. Make sure to ask your healthcare provider before consuming this medicine.
Abbott
Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.