Zerodol Spas Tablet

Zerodol Spas Tablet is a combination of two medicine known as Drotaverine (80mg) and Aceclofenac (100mg). It is prescribed to treat abdominal pain as it works effectively to reduce abdominal pain, bloating, discomfort and cramps by relaxing the muscles of the stomach and gut.

It acts by blocking certain types of chemical messengers that cause pain and discomfort. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose.​

• Treatment of Abdominal pain

Zerodol Spas Tablet can cause multiple side effects, most of which are mild to moderate and often temporary. Patients are advised to inform their healthcare provider immediately if symptoms stays for prolonged period of time.

• Diarrhea
• Nausea
• Vomiting
• Dryness in mouth
• Dizziness
• Vertigo
• Insomnia (difficulty in sleeping)
• Hypotension (low blood pressure)
• Fast heart rate
• Sweating
• Constipation
• Indigestion
• Abdominal pain
• Increased liver enzymes

• Doctor determines the exact dose and duration with Zerodol Spas Tablet as per the overall health condition of the patient. This tablet should be taken with food at the fix time every day to get effective results.
• Don't miss a dose or overdose on the medicine. Swallow it as a whole with a glass of water and do not crush, chew, or open it.​​
  

• Zerodol Spas Tablet is a combination of two medicine known as Drotaverine (80mg) and Aceclofenac (100mg). Drotaverine is known asan anti-spasmodic medication which reduces abdominal smooth muscle contractions, or spasms.
• One kind of non-steroidal anti-inflammatory medicine (NSAID) is aceclofenac. It acts by preventing the formation of specific chemicals that result in inflammation (swelling) and discomfort in the abdomen.​​
  

• Hajera, K., Shahed, M., Zaheer, Z., & Nazia, K. (2012). Simultaneous spectrophotometric estimation of aceclofenac and drotaverine hydrochloride in tablet dosage form. International Journal of Advanced Research in Pharmaceutical & Bio Sciences, 2(1), 432-439. Simultaneous spectrophotometric estimation of aceclofenac and drotaverine hydrochloride in tablet dosage form
• Wankhede, S. B., Mahale, D. K., & Chitlange, S. S. (2010). Stability-indicating HPTLC method for simultaneous determinationof Drotaverine and Aceclofenac in tablet formulation. Der. Pharma. Chemica, 2(5), 107-117.
• Choudhari, V., Ingale, K., Sahoo, M., Syal, P., Ingale, S., Shinde, S., ... & Kuchekar, B. (2010). Development and validation of a RP-HPLC-PDA method for simultaneous estimation of Drotaverine and Aceclofenac in a combined dosage form. International Journal of Research in Pharmaceutical Sciences, 1(3), 253-258.https://www.researchgate.net/publication/49600758_Development_and_validation_of_a_RP-HPLC-PDA_method_for_simultaneous_estimation_of_Drotaverine_and_Aceclofenac_in_a_combined_dosage_form
• Vinod, K. M., & Ashish, D. (2013). Oral drotaverine and aceclofenac combination versus aceclofenac alone for postoperative pain relief: A prospective randomized clinical trial. Indian Journal of Pharmacy Practice, 6(4), 18.
• Pareek, A., Chandurkar, N. B., Patil, R. T., Agrawal, S. N., Uday, R. B., & Tambe, S. G. (2010). Efficacy and safety of aceclofenac and drotaverine fixed-dose combination in the treatment of primary dysmenorrhoea: a double-blind, double-dummy, randomized comparative study with aceclofenac. European Journal of Obstetrics & Gynecology and Reproductive Biology, 152(1), 86-90.