How many doses of Avaxim 0.5 ml are required for their function?

For children above 2 years, the vaccine is administered in the deltoid muscle of the upper arm, while for children under 2 years of age, the injection is given in the anterolateral aspect of the thigh. A booster dose of 0.5 ml is recommended for long-term protection, which should be given between 6 and 36 months after the initial dose of vaccination. These two doses provide long-lasting immunity for at least 20 years.

Avaxim 0.5 ml vaccine is recommended mainly for?

People traveling to high-risk countries, during poor sanitation or outbreak conditions, children living in areas where hepatitis A is more prevalent, and children with health problems, especially chronic liver disease.

Does Avaxim 0.5 ml interfere with other vaccines?

More than one vaccine should not be given at the same site or with the same injection. However, they can be separately administered.

Can I get a fever after taking the Avaxim 0.5 ml vaccine?

Fever, headache, fatigue, and redness or pain at the site of injection are the common side effects caused by taking a vaccine due to an immune response.

After taking the Avaxim 0.5 ml vaccine, can children go to school?

Fever, redness or pain in the body, soreness, and fatigue generally occur after taking the Avaxim 0.5 ml vaccine due to the immune response of the body against the hepatitis virus. However, children can go to school with it, and it doesn't affect normal activities.

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Avaxim 0.5ml Vaccine

Name: Avaxim 0.5ml Vaccine
Brand: Avaxim
Price: 1343 INR
Availability: InStock
Rating: 4.71 (7 reviews)

Rx Required

Refrigerated 2–8°C · Online payment only

Salt Composition: Freeze-dried Live Attenuated Hepatitis A Vaccine (80IU)

Expiry Date: 01/2028

Price on Request

Inclusive of all taxes

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1 Vial in a Pack

About The Product

Hepatitis A

The Avaxim 0.5 ml vaccine protects the individual from hepatitis A, which is a liver disease caused by the hepatitis A virus (HAV). It is spread by contaminated water or food or close personal contact with the infected person. The vaccine is produced by killing or inactivating the hepatitis A virus. The Avaxim 0.5 ml vaccine is injected intramuscularly, typically into the upper arm muscle (deltoid), which results in the production of antibodies against the virus without causing the disease. This vaccine is not for other liver diseases or hepatitis B, C, or E. It can be used for both adults and children; for children, it contains a lower amount of antigen, i.e., 80 Elisa Units (EU), while there are 160 EU in 0.5 ml of Avaxim for adults.

Side Effects

Undesired symptoms or responses vary from individual to individual as the human body reacts differently to the Avaxim 0.5 ml vaccine.
But they disappear within a few days naturally as the body adjusts to the vaccine, which requires no medical attention.
In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team.
Some of the common side effects of the Avaxim 0.5 ml vaccine are: Fatigue Headache Irritability Fever loss of appetite Nausea Pain, redness or swelling at injection site

How To Use

The Avaxim 0.5 ml vaccine contains inactivated hepatitis A virus and is meant for children in the age group 12 months to 15 years.
The single 0.5 ml dose is given intramuscularly.
For children above 2 years, the vaccine is administered in the deltoid muscle of the upper arm, while for children under 2 years of age, the injection is given in the anterolateral aspect of the thigh.
A booster dose of 0.5 ml is recommended for long-term protection, which should be given between 6 and 36 months after the initial dose of vaccination.
These two doses provide long-lasting immunity for at least 20 years.
The Avaxim 0.5 ml vaccine should not be self-administered; it should not be given intradermally, intravascularly, or subcutaneously by healthcare experts.
Do not use the same injection or syringe for another vaccine, as there are chance of the products interacting.
Always check the vial of vaccine before using it for discoloration or any kind of particulate matter, and shake well for uniform mixing of the product.

How It Works

The Avaxim 0.5 ml vaccine contains killed or inactivated hepatitis A virus (HAV) that stimulates the immune system to produce antibodies against the virus but doesn’t cause disease. These antibodies and memory cells formed after taking the injection identify and counteract the virus and generate memory for the hepatitis virus, and neutralize it with a stronger immune response upon subsequent exposure within a few hours.

This provides immunity within 2 to 4 weeks and for many years after taking a booster dose.

Safety Advice

Alcohol

Excessive alcohol consumption can decrease the immunity of the individual and weaken the liver function. However, moderate levels of alcohol do not interfere with the working of the Avaxim 0.5 ml vaccine, as per the research. People with liver disease caused mainly by drinking alcohol are advised to be vaccinated.

Pregnancy

The Avaxim 0.5 ml vaccine should be injected after consulting the doctor; during pregnancy, it is not suggested to take it routinely. However, if the risk of hepatitis A is high, then it may be used if needed after taking advice from the medical experts.

Breast Feeding

The Avaxim 0.5 ml vaccine can be taken while breastfeeding after discussion with your doctor. It is generally considered safe, and there is no clear evidence found in the clinical data to harm the baby.

Driving

Driving after taking the Avaxim 0.5 ml vaccine does not affect or interfere with driving ability or disturb while operating machinery. However, if you get a fever or dizziness after the injection, avoid driving until you feel better.

Kidney

The Avaxim 0.5 ml vaccine is considered safe for people with kidney problems, including individuals on dialysis. The Avaxim 0.5 ml vaccine is considered safe for people with kidney problems, including individuals on dialysis. Although the immune response may be reduced in patients having kidney problems but it is generally recommended to take the vaccine after discussing with your doctor or medical experts.

Liver

The Avaxim 0.5 ml vaccine is generally considered beneficial and safe for people with chronic liver disease, and vaccination is strongly recommended for people who are at high risk of getting severe hepatitis A infection.

FAQs

The Avaxim 0.5 ml vaccine is injected intramuscularly, typically into the upper arm muscle (deltoid).

The Avaxim 0.5 ml vaccine should not be self-administered; it should not be given intradermally, intravascularly, or subcutaneously by healthcare experts.

Reference

Abarca, K., Ibáñez, I., Perret, C., Vial, P., & Zinsou, J. A.

(2023). Immunogenicity, safety, and interchangeability of two inactivated hepatitis A vaccines in Chilean children.

International Journal of Infectious Diseases, 12(3), 270-277. Kim, H., Oh, Y., Thollot, Y., & Bravo, C.

(2024). Post-marketing surveillance of hepatitis A virus vaccine (Avaxim® 160U) in South Korea from 2011 to 2015.

Infectious Diseases and Therapy, 8(1), 105-112. Li, R.

C., Li, Y., Yi, N., Huang, L., Wan, Z., Zhang, Y., & Rasuli, A. (2023).

An open, prospective, randomized study comparing the immunogenicity and safety of two inactivated hepatitis A pediatric vaccines in toddlers, children, and adolescents in China. The Pediatric Infectious Disease Journal, 32(2), e77-e81.

Soysal, A., Gokçe, I., Pehlivan, T., & Bakir, M. (2025).

Interchangeability of a hepatitis A vaccine second dose: Avaxim 80 following a first dose of Vaqta 25 or Havrix 720 in children in Turkey. European journal of pediatrics, 166(6), 533-539.

Zuckerman, J. N., Kirkpatrick, C.

T., & Huang, M. (2023).

Immunogenicity and reactogenicity of Avaxim (160 AU) as compared with Havrix (1440 EL. U) as a booster following primary immunization with Havrix (1440 EL.

U) against hepatitis A. Journal of Travel Medicine, 5(1), 18-22.

Last updated: 5 Aug 2026 | 04:33 PM (IST)

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