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APRECAP 125/80 CAPSULE

Mfd. by :- Zydus (Fulfilled By : Magicine Pharma)

Aprecap 125/80 Capsule

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand name – Aprecap 125/80mg capsule

Generic name – Aprepitant

Manufacturer – Zydus

Strength – 125mg and 80mg

Dosage Form – Capsules

Composition – Aprecap

Indication – Against the side effects of Chemotherapy

Storage – at room temperature

 

Overview Of Aprecap 125/80mg capsule

Aprecap 125 / 80mg capsules are antiemetic medications that reduce the side effects of getting chemotherapy. The generic name of this medication is Aprepitant and it is a neurokinin1 receptor antagonist. It reduces nausea and vomiting in the patients who undergo cancer treatment. It is a strictly prescription-based medication.

Pharmacodynamics

Aprecap is an antiemetic drug that is it stops the nausea and vomiting caused by anticancer medications.  It is a substance P/ neurokinin 1 receptor antagonist. This medication crosses the blood-brain barrier and binds to the NK1 receptors. As a result, it stops the nausea and vomiting which occur as side effects of the medicine.

  • Dizziness
  • Heartburn
  • Extreme fatigue
  • Loss of appetite
  • Fever
  • Itching
  • Hair loss
  • Indigestion
  • Constipation
  • Shortness of breath
  • Difficulty in swallowing
  • Rashes and hives on the skin
  • Blisters on the skin

This medicine is prescribed by the doctor hence, it is advisable to follow the prescription given. Aprecap 125mg/80 mg capsules is taken orally once every day and it can be taken with or without food.

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Aprecap capsules consult your doctor immediately.

Overdose

In case of an overdose on Aprecap 125mg /80mg, contact your doctor or any healthcare provider and seek medical attention immediately.

  • Aprecap can cause an allergic reaction in some patients. Therefore it is better to read the complete composition before use and consult the doctor to find an alternative.
  • Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription medications. 
  • It is advisable to avoid pregnancy and breastfeeding during and till one month after the last dose of Aprecap tablets since it can harm the fetus. Also, use additional contraceptives in case you are using hormonal contraceptives.
  • Avoid alcohol consumption and also avoid driving and operating heavy machinery.
  • Inform the doctor if you have a past medical history of liver disease.

Q - What is Aprecap?

Ans – Aprecap is an antiemetic capsule that is primarily used to reduce the side effects like nausea and vomiting caused by chemotherapy or any other cancer treatments.

Q - How can I take Aprecap 125mg/80mg capsules?

Ans - Aprecap 125mg/80mg capsules are taken orally once every day. However, it is advisable to follow the prescription given by the doctor.

Q – From where can I purchase Aprecap 125mg/80mg capsules?

Ans - Aprecap 125mg/80mg capsules can be purchased from Magicine Pharma at a reasonable rate.

Q - Where can I store Aprecap tablets?

Ans - It is advisable to store the tablets at a place below 30°C.

Q - Can I drink alcohol with Aprecap?

Ans – it is advisable to avoid drinking alcohol during the treatment with Aprecap 80mg capsules even though no interactions of both are known.

Q - How long is the treatment with Aprecap 125mg/80mg capsules?

Ans - The doctor decides the course and dosage of Aprecap capsules.

Q - Can I drive after consuming Aprecap?

Ans - It is advisable to avoid driving and operating heavy machinery as Aprecap capsules cause dizziness as one of the side effects.

Q - Is it safe to take Aprecap 125mg during pregnancy?

Ans – No, since Aprecap can cause harm to the fetus it is advisable to avoid pregnancy and breastfeeding during and till one month after the last dose.

Q - What is the strength of Aprecap capsules?

Ans – Aprecap is available in capsule form in two strengths – 125mg and 80mg. The doctor decides which strength should be prescribed to the patient.

Aprecap 125mg capsules can interact with other prescription and non-prescription medicines and interfere with each other’s workings or increase the side effects. Inform the doctor if you take these –

  • Warfarin
  • Pimozide
  • Benzodiazepines
  • Dexamethasone
  • Methylprednisolone
  • Hormonal contraceptives
  • Chemotherapy drugs working on CYP 34 (Vinblastine, Vincristine )
  • 5-HT3 Antagonists
  • Rifampin
  • Phenytoin
  • Ritonavir
  • Ketoconazole

With disease

Some diseases may show interactions with. Hence, consult your doctor if you have any of these conditions –

  • Liver (hepatic)disorders

With alcohol

Interactions of alcohol with Aprecap 125mg capsules are unknown. However, it is still advisable to avoid alcohol consumption during the treatment.

Contraindication

Aprecap 125mg capsules should not be consumed by patients who show allergic reactions to it. In addition, it should not be given to patients who take Pimozide (Orap).

 

Alternate Brands

  • EMED
  • Apretero
  • Apriset
  • Opilo
  • Piptashil 

Reference

DailyMed - emend- aprepitant capsule EMEND- aprepitant kit emend- aprepitant powder, for suspension U.S. National Library of Medicine. Available at: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=696f9e80-9cae-403b-de9e-078343ce4713#section-10.

Aprepitant Uses, Interactions, Mechanism of Action | DrugBank Online. Available at: https://go.drugbank.com/drugs/DB00673.

Aprepitant: MedlinePlus Drug Information MedlinePlus. Available at: https://medlineplus.gov/druginfo/meds/a604003.html.

Above Content has been reviewed by Professionals