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ALBUMIN BOUND PACLITAXEL 100 MG INJECTION (ABRA-BOUND)

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Albumin Bound Paclitaxel 100 mg Injection (Abra-Bound)

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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PACKAGE

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Brand Name:- Abra-Bound
Generic Name:- Albumin Bound Paclitaxel
Manufacturer:- Arechar Healthcare
Strength:- 100 mg
Dosage:- Injection
Storage:- Store at room temperature (10-30°C)
Indication:- Breast Cancer, Lung Cancer, Pancreatic Cancer
Prescription required:- Yes

Overview

Abra-Bound (Albumin Bound Paclitaxel) injection is an anti-cancer medication. It is used to treat certain types of cancers including Breast Cancer, Lung Cancer, and Pancreatic Cancer. Abra-Bound is available in the form of an injection in the strength of 100 mg. Paclitaxel 100mg injection is given into the vein of the patient, by a medical practitioner. Paclitaxel 100mg injection may be prescribed in combination with other anti-cancer regimens for better efficacy. It is important to not miss a scheduled dose. 

Pharmacodynamics of Paclitaxel 100mg injection

Paclitaxel is a taxoid antineoplastic agent indicated as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast cancer. It is a novel antimicrotubule agent. It promotes the assembly of microtubules from tubulin dimers. Also, it stabilizes microtubules by preventing depolymerization. This stability further results in the inhibition of the normal dynamic reorganization of the microtubule network. This is essential for vital interphase and mitotic cellular functions. Paclitaxel works to induce abnormal arrays or "bundles" of microtubules throughout the cell cycle and multiple asters of microtubules during mitosis.

Usage of Paclitaxel 100mg injection

Abra-Bound is an injectable formulation of Paclitaxel, which is prescribed for the treatment of certain types of cancers such as Breast Cancer, Lung Cancer, and Pancreatic Cancer. Abra-Bound comprises Albumin Bound Paclitaxel. It works to kill cancer cells. It is one of the best anti-cancer formulations. The dose strength and duration of the Paclitaxel 100mg injection will be decided by your healthcare provider. It is advised to not stop taking Abra-Bound (Albumin Bound Paclitaxel) injection without contacting a medical practitioner. 

Side effect of Paclitaxel 100mg injection

The side effects of Abra-Bound (Albumin Bound Paclitaxel) injection are mentioned below. It is important to consult a medical practitioner in case these/other side effects occur.

  • Diarrhea

  • Nausea

  • Fever

  • Chills

  • Vomiting

  • Chest pain

  • Skin rash

  • Itching

  • Allergic reaction

  • Cough 

  • Constipation

  • Tiredness

  • Weakness

  • Drowsiness

  • Sore throat

  • Difficulty in breathing

  • Mouth ulcers

  • Painful urination

  • Hairloss

  • Neutropenia

  • Fainting

  • Blurred vision

  • Pale skin

  • Anemia

  • Redness on skin

  • Swelling on face

Normal Dose

It is advisable to not self--administer Abra-Bound (Albumin Bound Paclitaxel) injection. Your healthcare provider will give you Paclitaxel 100mg injection according to your medical condition.

Missed Dose

Initially, it is advisable to not miss a dose. However, if such a case happens, make sure to consult your healthcare provider to schedule an appointment for the same or guide you further.

Overdose

In case you experience symptoms of overdose, immediately call your doctor or any other medical emergency helpline.

 

Cautions to be followed while taking Paclitaxel 100mg injection

Pregnancy or Breastfeeding

During Pregnancy or Breastfeeding, Abra-Bound (Albumin Bound Paclitaxel) injection is not prescribed for use unless necessary. It is advisable to consult your doctor regarding the potential risks and benefits of this injection.

Driving

After taking Abra-Bound (Albumin Bound Paclitaxel) injection, side effects like blurred vision or tiredness may occur. Hence, it is advised to avoid any such activity that demands high concentration (including driving and operating heavy machinery).

Heart or Respiratory Disease

Abra-Bound (Albumin Bound Paclitaxel) injection should be administered with caution in patients having a known heart or respiratory disease (including diabetes). Prior discussion with the doctor about the risks and benefits is recommended.

Things to Avoid while taking Paclitaxel 100mg injection

  • Alcohol

  • Driving

  • Unwashed fruits and vegetables

  • Raw meat

Q1- What is Abra-Bound (Albumin Bound Paclitaxel) injection used for?

Ans- Abra-Bound (Albumin Bound Paclitaxel) injection is an anti-cancer medication, prescribed for the treatment of Breast Cancer, Lung Cancer, and Pancreatic Cancer.

Q2- What are the side effects of Abra-Bound (Albumin Bound Paclitaxel) injection?

Ans- The side effects of Abra-Bound 100 mg injection are fever, nausea, chills, skin rash, itching, vomiting, swelling on the face, diarrhea, anemia, etc. Also, other side effects may occur. Therefore, make sure to call your doctor if the condition worsens.

Q3- How can I take Paclitaxel 100mg injection?

Ans- It is advisable to not self-administer Abra-Bound 100 mg injection. Your healthcare provider will give you this injection according to your medical condition.

Q4- How should I store Abra-Bound 100 mg injection?

Ans- Store Abra-Bound (Albumin Bound Paclitaxel) injection at room temperature (10-30°C).

Q5- What is the strength of Abra-Bound (Albumin Bound Paclitaxel) injection?

Ans- Abra-Bound (Albumin Bound Paclitaxel) injection is available in the strength of 100 mg. It is available in the form of an injection, given by a healthcare provider. 

Q6- Is it safe to drive after taking Abra-Bound (Albumin Bound Paclitaxel) injection?

Ans- It may not be safe to drive after taking Abra-Bound (Albumin Bound Paclitaxel) injection as it may cause side effects such as drowsiness and lack of concentration. 

Q7- Is it safe to take Abra-Bound (Albumin Bound Paclitaxel) injection during pregnancy or breastfeeding?

Ans- It may not be safe to take Abra-Bound 100 mg injection during pregnancy or breastfeeding as this injection may harm the baby. Therefore, make sure to discuss the potential risks and benefits of taking this medicine. 

Q8- What should I avoid while taking Abra-Bound (Albumin Bound Paclitaxel) injection?

Ans- Avoid the following while taking Abra-Bound (Albumin Bound Paclitaxel) injection:

  • Raw meat

  • Alcohol 

Q9- How long should I take Paclitaxel 100mg injection?

Ans- Your doctor will decide the dose strength and duration of this medicine. Do not stop taking this medicine unless your healthcare provider tells you. 

Q10- Can I drink alcohol with Paclitaxel 100mg injection?

Ans- Alcohol may cause harm. However, the interaction of this medicine with alcohol is unknown. Make sure to consult your doctor for the same.

Interactions

All the medicines interact in different manners from person to person. Therefore, it is advisable to consult a healthcare professional to discuss this before the consumption of the Paclitaxel 100mg injection.

Interaction with Alcohol

Interaction with alcohol is unknown. Therefore, be sure to consult your doctor.

Interaction with Medicine 

  • Atorvastatin
  • Live vaccines
  • Clozapine
  • Diltiazem

Disease Interaction

  • Cardiac Conduction Abnormalities

Alternate Brands

  • Abraxane
  • Nab Paclitero

Contraindications

  • Abra-Bound (Albumin Bound Paclitaxel) injection is not indicated for use in patients who have an allergy to Paclitaxel or other ingredients of Abra-Bound.
  • Paclitaxel 100mg injection is also not indicated for use in patients who have a low count of Neutrophils.

 

Reference

Paclitaxel: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB01229

Paclitaxel (with albumin) Injection: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a619008.html

Above Content has been reviewed by Professionals