Azadine 100mg Injection
Salt Composition: Azacitidine
Expiry Date: 01/2028
Price on Request
Inclusive of all taxes
1 injection
About The Product
- Myelodysplastic Syndromes (MDS)
- Acute Myeloid Leukemia (AML)
- Chronic Myelomonocytic Leukemia (CMML)
- Azadine, or azacitidine, is one of the medications that are used in cancer chemotherapy for curing blood cancers and bone marrow cancer.
- It works as a hypomethylating agent by affecting gene regulation responsible for controlling the production of abnormal blood cells within the bone marrow.
- This medication can be injected into the patient's body via subcutaneous injection or intravenous infusion by trained personnel.
- Antinausea medication is usually prescribed before administration of the injection to prevent nausea.
- Monitoring of blood counts is mandatory throughout the treatment period.
- Possible adverse effects of this injection include nausea, vomiting, diarrhea, constipation, anemia, neutropenia, and skin irritation around the injection site.
- Azadine should never be taken during pregnancy or when breastfeeding since it poses serious risks to the baby.
Side Effects
Azadine 100mg injection may cause some common side effects that vary from patient to patient. Discuss the risks and benefits of injection with the doctor before starting the treatment. In case of any serious or persistent effect, seek medical attention immediately. Side effects include:
- Injection site reactions (pain, redness, swelling)
- Nausea and vomiting
- Diarrhea or constipation
- Loss of appetite
- Weakness, tiredness, or dizziness
- Headache or severe headache
- Fever and chills
- Stomach pain
- Sore throat, nose irritation, or voice changes
- Skin rashes, bruising, or itching
- Pain in joints or extremities
- Decreased potassium levels in blood
- Disturbances in blood counts (low red, white cells, or platelets)
- Pneumonia with chest pain or breathlessness
- Allergic reactions (lip swelling, itching, rash)
- Seizures, loss of consciousness, or bleeding in the brain
- Frequent urination with pain or burning sensation
- Unexpected bleeding (blood in stool or urine)
How To Use
- Azadine 100mg injection is a powerful anticancer medicine that can only be given by a doctor or nurse under strict medical supervision.
- Do not self-administer.
- Dosage and duration of treatment of this injection are determined by the doctor according to the patient's health condition.
Safety Advice
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Azadine 100mg injection.
Do not take Azadine 100mg injection, as it is unsafe for the fetus.
Azacitidine injection is unsafe to use during breastfeeding as it may cause toxicity to the baby.
Azadine 100mg injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Consumption of Azacitidine injection should be avoided without informing the doctor if you have any kidney-related issues.
Consumption of Azadine 100mg injection should be avoided without informing the doctor if you have any liver-related issues.
Missed Doses
- In case you missed any dose of Azadine 100mg injection, consult your doctor.
FAQs
Azadine 100mg injection is used for the treatment of chronic myelomonocytic leukaemia (CMML), acute myeloid leukaemia (AML), and Myelodysplastic Syndrome (MDS).
References
- https://www.ncbi.nlm.nih.gov/books/NBK602611/
- https://www.tga.gov.au/resources/cancellations-by-sponsors/azadine-azacitidine-100-mg-powder-injection-vial-cancelled-under-section-301c-act
- Leung, C., Tingley, K., & McGill, S. C. (2022). Subcutaneous injection of azacitidine for the treatment of acute myeloid leukemia. Canadian Journal of Health Technologies, 2(10).
- Verbruggen, L., Sprimont, L., Bentea, E., Janssen, P., Gharib, A., Deneyer, L., ... & Massie, A. (2021). Chronic sulfasalazine treatment in mice induces system xc−-independent adverse effects. Frontiers in pharmacology, 12, 625699.
- Boutet, K., Montani, D., Jaïs, X., Yaïci, A., Sitbon, O., Simonneau, G., & Humbert, M. (2008). Therapeutic advances in pulmonary arterial hypertension. Therapeutic advances in respiratory disease, 2(4), 249-265.
Medical Disclaimer
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The content on this website has been produced solely for informational purposes. This is not intended to take the place of medical advice and care provided by a licensed professional, though.
This information may not include all potential side effects, warnings, and details about specific lab tests, medications, and medical conditions. Please ask your doctor any questions you may have about any drug or disease.
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