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Bortenat 2mg Injection

Bortenat 2mg Injection

Prescription requiredRx Required

Salt Composition: Bortezomib

Expiry Date: 01/2028

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1 Injection

About The Product

Multiple myeloma

Mantle-cell lymphoma and multiple myeloma can be treated with Bortenat 2mg injections. By inhibiting or reducing the proliferation of cancer cells, it displays its efficacy. Only a physician or a qualified nurse can administer an intravenous injection of  Boratenat 2mg. It contains Bortezomib(2mg) in composition.

Uses

Multiple myeloma
Mantle-cell lymphoma

Side Effects

  • Most side effects of Bortenat 2mg injection do not require medical attention as they may disappear as your body adjusts to the medicine.
  • In case these side effects become worse, consult your doctor immediately. ​Dizziness Tingling of hands and arms Sore throat Shortness of breath Increased bleeding Fever Chills Wheezing Muscle cramps Constipation Nausea Vomiting Loss of appetite Stomach pain

Dosage and Administration

  • Bortenat 2mg injection is a prescription-based medication that should be injected intravenously by a doctor or an experienced nurse.
  • In case of an overdose of Bortenat, contact your doctor or any healthcare provider and seek medical attention immediately

Mechanism of action

Bortenat 2mg injection is a dipeptide boronic acid derivative that functions as a proteasome inhibitor. It interferes with the functioning of the 26S proteasome, which furthermore causes apoptosis in cancerous cells.

Additionally, it arrests the cell cycle in the middle. Bortenat suppresses the NF–κB signaling pathway, which is associated with anti-apoptotic genes.

Thus, Bortenat 2mg suppresses the tumours progressively.

Safety Advice

Alcohol
It is advisable not to consume alcohol while taking medicine.
Pregnancy
Do not take ​Bortenat 2mg injection without consulting the doctor, in case of pregnancy.
Breast Feeding
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
Do not take ​Bortenat 2mg injection without a doctor's consultation in case of kidney problems.
Liver
Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

  • It is advisable not to miss any dose.
  • In case you miss a dose of Bortenat 2mg injection consult your doctor soon.
  • Missing the dose will impact the overall health of the patients.
  • So, it is always advisable to follow the prescription of the doctor strictly.

FAQs

Bortenat 2mg injection/vial is an anticancer injection that is primarily used in the treatment of multiple myeloma.


Reference

San Miguel, J. F., Schlag, R., Khuageva, N. K., Dimopoulos, M. A., Shpilberg, O., Kropff, M., Richardson, P. G. (2008). Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. New England Journal of Medicine, 359(9), 906–917. https://doi.org/10.1056/NEJMoa0801479.

Bortezomib‐containing regimens are effective in multiple myeloma—results of a non-interventional study. Phase IV (2015). Blood Cancer Journal. https://doi.org/10.1038/srep06944

Bortezomib therapy in a real-world setting in patients with relapsed or refractory multiple myeloma. (2019). Translational Cancer Research, 8(6), 2019. https://doi.org/10.21037/tcr.2019.09.18

Real-world medical practice use of bortezomib-based therapy in RRMM: the VELCADE® Observational Study. (2018). Clinical Lymphoma, Myeloma & Leukemia, 18(4), e205–e212. https://doi.org/10.1016/j.clml.2018.03.010

Certified Content

Written By
Venika Choudhary

Venika Choudhary

Medical Content Writer @ Magicine Pharma

Reviewed By
Dr. Aditya Sarin

Dr. Aditya Sarin

MBBS, MD - General Medicine, DrNB - Medical Oncology | 11 Years Experience

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