Brand Name:- Keytruda
Generic Name:- Pembrolizumab
Strength :- 100mg/4ml
Dosage Form:- Injection
Packaging Size:- 1 vial
Manufacturer:- Merck sharp
Indications:- Head and neck cancer, lung cancer, skin cancer, gastric cancer
Storage:- Store in a cool and dry place
Keytruda injection (Pembrolizumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is used with other types of medicine to cure certain types of cancers such as lung cancer, skin cancer, gastric cancer, liver cancer. This medicine is used to treat a kind of lung cancer called non-small cell lung cancer. It is an immunotherapy that works with your immune system to fight cancer. Keytruda is often given when cancer has spread to other parts of the body and cannot be treated with chemotherapy or radiation therapy. Keytruda can cause side effects in different parts of your body.
Keytruda 100mg Injection (Pembrolizymab) indications
It is indicated for the treatment of patients with metastatic myeloma.
It is indicated for the treatment of small-cell lung cancer
It is indicated for the treatment of adult and pediatric patients with metastatic microsatellite instability-high(MSI-H).
Keytruda, in combination with axitinib, is indicated for the first-line treatment of patients with advanced renal cell carcinoma RCC.
Side effect of Keytruda 100mg Injection (Pembrolizumab)
It may cause some unwanted effect. Although all of these side effects may not occur, if they occur it requires immediate medical attention.
Common side effect
Bloating or swelling in the face, arms, legs, and feet.
Runny or stuffy nose
Unusual weight gain or loss
Change in eyesight
Yellow eyes or skin
Severe or sudden headache
Redness of eye
Loss of appetite
NOTE:- Immediately contact your doctor if any of these side effects occur.
Usage of Keytruda injection (Pembrolizumab)
Keytruda injection (Pembrolizumab) is used to treat both small cell lung cancer and non-small cell cancer. This type of lung cancer is the most common. It is approved to treat melanoma that can’t be removed surgically.
The drug is used to prevent skin cancer from coming back. It is also approved to treat certain types of bladder cancer. For this use, keytruda is given to people who have chosen not to have surgery for their cancer.
Warnings and precautions
Before taking kedura talk to your doctor about your medical history. It may not be right for you in certain medical conditions.
It may cause some severe effect on your immune system
If you’ve had an allogeneic stem transplant, consult your doctor about keytruda.
Using keytruda with certain other drugs may increase the risk of death.
It is not safe for pregnant woman, as it may cause harm to the unborn baby
Breastfeeding is not recommended for women who are taking keytruda.
It may cause some allergic reaction, please consult your doctor.
May harm the immune system
Do not drive after taking this medication
Not safe for pregnant women
Do not take this medication without doctor advice
Q1. What is the use of Keytruda injection?
Ans. Pemrulizumab blocks the PD-1 (type of protein) receptor, preventing binding and activation of PD-L1 and PD-L2. This process results in the activation of T-cell mediated immune responses in contrast to tumor cells.
Q2. How does this medication work?
Ans. keytruda is a type of immunotherapy that works by blocking the PD-1 pathway and to help prevent cancer cells from hiding. Keytruda helps the immune system to detect and fight cancer.
Q3. What are the side effects of Keytruda injection?
Ans. common side effects are vomiting, skin rash, nausea, blurred vision, dizziness, constipation, sore throat, pale skin, muscle cramps etc.
Q4.In what strengths is it available?
Ans. It is available in 100mg/4ml solution in a single dose vial.
Q5. Is Keytruda injection an immunotherapy?
Ans. keytruda is an immunotherapy medicine that may treat certain cancers by working with your immune system. Immunotherapy is a type of cancer treatment that uses your own immune system to help detect and fight cancer.
Q6. How long does it take to effect?
Ans. It usually takes 30 minutes after you have it.
Q7.What are the signs that show keytruda is working?
Ans. It is measured by a shrinking or stable tumor. During and after treatment, the patient will have a regular checkup with his or her physician.
Q8.When should patients notify their physician?
Ans. If you have symptoms of lung problem(shortness of breath, chest pain), kidney problem and other signs of problem with other organs like:- rash, change in eyesight, severe muscle weakness.
Q9. How will I receive Keytruda injection?
Ans. Your doctor will give you an injection into your vein. It is given every 3 weeks. Your doctor will decide how many treatments you need.
Q10. How are patients taking keytruda monitored?
Ans. Patients receiving keytruda are monitored with blood work and other laboratory tests to check the adverse reaction on the immune system like:- changes in kidney and thyroid function, hepatitis, colitis and pneumonitis.
Q11. Can I take this medicine during pregnancy?
Ans. This medication is not recommended for pregnant womens, because it may harm the unborn baby.
Q12. Can this medicine be taken during breast feeding?
Ans It is unsafe during breastfeeding, that’s why it is not recommended for breastfeeding womens.
Q13. What if I miss a dose?
Ans. Contact your doctor immediately, in case you miss a dose.
Q14. What should I avoid while receiving a Keytruda injection?
Ans. It can pass into body fluids(urine, vomits). For 48 hours after taking a dose, avoid allowing your body fluid to come in contact with your hand or other surfaces.
Keytruda 100mg (Pembrolizumab) interaction
Keytruda: Drug information available at: https://go.drugbank.com/drugs/DB09037
Keytruda: Drug Uses, mechanism, and Side Effects available at: https://www.mayoclinic.org/drugs-supplements/pembrolizumab-intravenous-route/side-effects/drg-20122552 and https://www.keytruda.com/side-effects/.