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TECENTRIQ 1200MG INJECTION

Mfd. by :- Roche Products India Pvt Ltd (Fulfilled By : Magicine Pharma)

Tecentriq 1200mg Injection

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Medicine Details

Brand Name – Tecentriq

Generic Name – Atezolizumab

Manufacturer – Roche Products India Pvt. Ltd

Dosage – Injection

Strength – 1200 mg/20 mL (60 mg/mL)

Storage – Refrigerator (2° – 8° C)

Indication – Lung Cancer

Prescription required – Yes

Atezolizumab 1200mg/20mL injection also known by the brand name Tecentriq is an anticancer drug used in the treatment of lung cancer. It is a monoclonal antibody used to treat non-small cell lung cancer (NSCLC). It is also often used in combination with other medicines and can be used to treat small cell lung cancer. Atezolizumab blocks the effect of the proteins necessary for the functioning of cancer cells. It also stimulates immune cells to fight against the cancer cells.

Tecentriq 1200mg/20mL Injection vial (Atezolizumab) is administered as an intravenous infusion. It is a prescription-based drug. Therefore, the dosage, and duration of the medication will be decided by the doctor. Also, inform your doctor about all your prior medical conditions and allergies.

Mechanism of action

Atezolizumab (Tecentriq 1200mg Injection) is a monoclonal antibody that is used to treat non-small cell lung cancer. It functions by binding to PD (programmed death) ligand1 and interferes in the binding of PD recptor1 to it. This binding blocks the PD-1/PD-L1 pathway and furthermore, stimulates the immune response to fight against the cancer cells. This drug restores the antitumor T cell activity which attacks the cancer cells. This, as a result, stops the incontrollable growth and spreading of cancerous cells in the lungs.

Contraindication

  1. Allergies – Some components of Tecentriq Tecentriq 1200mg Injection (Atezolizumab) can start an allergic reaction. Hence, it is recommended to consult your doctor and find an appropriate alternative for this medicine.
  2. Pregnancy – Tecentriq 1200mg Injection (Atezolizumab) causes harm to the fetus hence, pregnancy should be avoided during and till 5 months after the last dose.
  3. Breastfeeding – Tecentriq 1200mg Injection (Atezolizumab) can pass through the milk thus, it is advised to stop breastfeeding during the treatment and till 5 months after the last dose.

 

Side Effects Of Tecentriq 1200mg Injection

Some of the common side effects of Tecentriq 1200mg Injection (Atezolizumab) which do not require medical attention –

  1. Common cold
  2. Loss of appetite
  3. Vomiting
  4. Constipation
  5. Diarrhea
  6. Stomach pain
  7. Headache
  8. Fever
  9. Chills
  10. Fatigue
  11. Breathlessness
  12. Dizziness
  13. Hair loss
  14. Sensitive skin
  15. Higher blood pressure

If you experience any of the symptoms mentioned below, contact your healthcare provider –

  1. Yellowing of skin and eyes
  2. Blood in urine and stool
  3. Rashes, swelling, and redness on the injection site
  4. Facial muscle paralysis
  5. Double or blurred vision

Low RBC count (Anemia)

Dosage

Tecentriq 1200mg Injection (Atezolizumab) is not self-administered. It will be prepared by the doctors as an intravenous infusion. The dosage and duration will depend on the stage and type of cancer.

Missed dosage

In case of a missed dosage, it is recommended to consult your doctor and book the next appointment immediately.

Storage

Not applicable for Tecentriq 1200mg Injection (Atezolizumab). Tecentriq should be given by a doctor. Thus, should not be stored at home.

Overdose

If you experience any signs of overdose, call your doctor or emergency helpline immediately.

Warnings

  1. Some ingredients of Atezolizumab (Tecentriq 1200mg Injection) might cause an allergic response. Redness, rashes, swelling around the injection site, wheezing and also breathlessness are some initial signs of allergy. Therefore, it is recommended to consult your doctor in case you experience any of the symptoms.
  2. Tecentriq can reduce fertility in women. So, discuss with your doctor regarding all the potential risks related to this drug.
  3.  Tecentriq 1200mg Injection (Atezolizumab) can interact with other medications and supplements which can interfere with its actions.
  4. Tecentriq 1200mg Injection (Atezolizumab) can harm the fetus. So, it is advisable to avoid pregnancy and breastfeeding.
  5. Regular use of Tecentriq 1200mg Injection (Atezolizumab) can make skin sensitive to sunburns. Wearing sunscreen and protective clothes every time while going out is recommended.
  6. Avoid taking alcohol during the treatment.
  7. Avoid driving or using heavy machinery.
  8. Consult your doctor if you have suffered from the following –
  1. Myasthenia gravis
  2. Gullain Barré syndrome
  3. Crohn’s disease
  4. Ulcerative colitis
  5. Thyroid issues
  6. Diabetes
  7. Kidney disease
  8. Pneumonitis or any other lung disorder
  1. Inform your doctor about past organ or bone marrow transplants.

FAQ

  • What is Tecentriq used for?

Tecentriq or Atezolizumab is an anticancer medicine used for the treatment of lung cancer.

  • How can I take Tecentriq?

Tecentriq 1200mg Injection (Atezolizumab) should not be self-administered and should be strictly administered by doctors only.

  • Is it safe to drive after taking Tecentriq?

It is not advised to drive after injecting Tecentriq as it may cause dizziness as a side effect.

  • Can I take alcohol during Tecentriq treatment?

Scientifically there have been no interactions found between alcohol and Tecentriq 1200mg Injection (Atezolizumab). However, it is still recommended to avoid alcohol during the treatment.

  • What strength is Tecentriq?

Tecentriq or Atezolozumab is available as 1200 mg/20mL.

  • For how long should I take Tecentriq treatment?

Tecentriq is a prescription-based medicine. All the doses and duration will be decided by the doctor.

Interactions

It is advisable to inform your doctor about all the medicines and vitamin supplements you take.

With Alcohol.

Interactions of Tecentriq 1200mg Injection(Atezolizumab) with alcohol are unknown. However, it is recommended to avoid alcohol during the treatment as it may cause dizziness.

With other medications

It might interact with other medicines. Therefore, it is recommended to inform your doctor about all the prescriptions you have.

 

Reference

  • Atezolizumab: Drugs information and usage are available at: - https://go.drugbank.com/drugs/DB11595 and https://www.drugs.com/atezolizumab.html.

Atezolizumab: Mechanism, side effects, and dosage are available at: - https://medlineplus.gov/druginfo/meds/a616035.html, https://www.webmd.com/drugs/2/drug-171808/atezolizumab-intravenous/details, and https://www.cancer.gov/about-cancer/treatment/drugs/atezolizumab.

Above Content has been reviewed by Professionals