Femistra 1mg Tablet
Prescription Required
Marketed By
zydus
Pack of
10 tablet
Salt Composition
Anastrozole
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
Femistra tablet is a hormone therapy medication that is used to treat breast cancer in postmenopausal women. Anastrozole is the generic name of this medication, and it is a competitive non-steroidal aromatase inhibitor. This medication is strictly prescription-based. Femistra tablet can be used with other possible treatment options like radiation, surgery, etc, or can be taken alone. Advanced breast cancer that has spread to different areas of the body or within the breast can also be cured with the Femistra tablet.
Indication
Breast Cancer
Uses
Breast cancer
Side Effects
Most side effects of Femistra 1mg Tablet do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Constipation
Diarrhea
Weight gain, Heartburn Loss of appetite
Hair thinning
Tingling of hands and feet
Trouble sleeping
Dizziness
Chest pain
Swelling of hands
Yellowing of skin and eyes
Vision complications
Vaginal bleeding
How To Use
The doctor prescribes this medicine; hence, it is advisable to follow the prescription. Femistra tablets are taken orally once a day, and they can be taken with or without food as advised by the doctor. Femistra tablet should be taken at the same time every day for maximum benefits. Contact your doctor or any healthcare provider in case of an overdose and seek medical attention immediately.
How It Works
In many breast cancers, estrogen stimulates the uncontrollable growth of cancerous cells. Aromatase enzyme, present mainly in the adrenal glands can convert the androgens to estrogen, and this estrogen furthermore influences the cancerous cells. Thus, Femistra is a non-steroidal inhibitor that competitively binds to the aromatase enzyme and stops the production of estrogen. As a result, it inhibits the growth and spreading of the tumor cells.
Safety Advice
Alcohol
unsafe
It is advisable not to consume alcohol while taking the Femistra tablet. It is suggested that to consult your doctor.
Pregnancy
consult your doctor
Do not take the Femistra tablet without consulting a doctor in case of pregnancy. Femistra tablet is considered not safe to use in case of pregnancy as it may harm the developing baby, according to research evidence.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding. Femistra tablet may cause toxicity to the developing baby as it may be transferred through the milk of the mother, so it's not considered safe to use Femistra tablet during breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine. Femistra Tablet can make you feel sleepy, affect your vision, alertness may be reduced. It is advised not to drive if these symptoms exist while taking Femistra Tablet.
Kidney
caution
Do not take the Femistra 1mg tablet without a doctor's consultation in case of kidney problems. Patients with severe kidney disease should use Femistra Tablet with caution, and the patient may require an adjustment in dose as recommended by the doctor. A Regular kidney test should be done to monitor the side effects of Femistra Tablet on the kidneys.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine. Patients with severe Liver disease should use Femistra Tablet with caution, and the patient may require an adjustment in dose as recommended by the doctor. A Regular liver test should be done to monitor the side effects of Femistra Tablet on the liver.
Missed Doses
If you forget to take a dose of Femistra 1mg tablet consult your doctor. Don’t double up the next dose to cope with the missed one unless your doctor recommends it.
FAQs
Femistra is an anticancer tablet that is primarily used in the treatment of breast cancer.
Femistra tablets are taken orally once every day. However, it is advisable to follow the prescription given by the doctor.
It is advisable to store the Femistra tablets at a place below 30°C.
The doctor decides the course of treatment with Femistra depending on the stage of cancer, and the health of the patient.
Femistra 1mg tablet should only be used in post-menopausal women. However, contact the doctor immediately if you have not undergone menopause and have taken the medication.
As soon as you remember, take the missed dose of Femistra Tablet. Double dose should be avoided, and you must go back to the regular schedule.
Regular monitoring of organs like liver, kidney, lungs, heart, etc, and blood tests for cholesterol levels and bone mineral density are recommended.
No, before taking any other medicines, please discuss it with your doctor, as Femitra tablet can interact with tamoxifen or oestrogen-containing products and may reduce the effectiveness of the Femitra tablet.
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Reference
1.Miller, W. R., Bartlett, J., Brodie, A. M., et al. (2020). Aromatase inhibitors: Are there differences between steroidal and nonsteroidal aromatase inhibitors, and do they matter? The Oncologist, 13(8), 829–837.
2.Anderson, W. F., Chatterjee, N., Ershler, W. B., et al. (2022). Estrogen receptor breast cancer phenotypes in the Surveillance, Epidemiology, and End Results database. Breast Cancer Research and Treatment, 76(1), 27–36.
3.Miller, W., Stuart, M., Sahmoud, T., et al. (2023). Anastrozole (‘Arimidex’) blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer. British Journal of Cancer, 87(9), 950–955.
4.Yang, Y., Pan, W., Tang, X., Wu, S., & Sun, X. (2025). A meta-analysis of randomized controlled trials comparing the efficacy and safety of anastrozole versus tamoxifen for breast cancer. Oncotarget, 8(29), 48362–48374.
5.Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), Davies, C., Godwin, J., et al. (2021). Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials. The Lancet, 378(9793), 771–784.
6.Ingle, J. N., Suman, V. J., Ma, C. X., et al. (2025). Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole. Steroids, 99(Pt A), 32–38.
7.Cairns, J., Ingle, J. N., Liu, M. C., et al. (2023). The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1. Breast Cancer Research, 21(1), 47.
8.Tang, M. R., Wang, Y. X., Guo, S., Han, S. Y., & Wang, D. (2022). CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway. Apoptosis, 17(9), 927
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