Mfd. by :- Everest (Fulfilled By : Magicine Pharma)

Ponaxen 45Mg | 15Mg Tablets


Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand name – Ponaxen

Generic name – Ponatinib

Manufacturer – Everest

Strength – 45mg, 15mg

Dosage Form – Tablet

Composition – Ponatinib

Indication – Leukemia

Storage – at room temperature

Overview of Ponaxen 45mg tablet

Ponaxen 45mg or 15mg tablet is a chemotherapy medication that is used to treat blood cancers like chronic myeloid leukemia. The generic name of this medication is Ponatinib. It is a kinase inhibitor that stops the progression of the disease as it stops the cell proliferation. It is an oral tablet that should not be taken with grapefruit as it can hinder its functioning.


Ponaxen is a kinase inhibitor that inhibits the functioning of Bcr-Abl tyrosine kinase protein. This protein is the one that causes the progression of leukemia. Ponaxen also stops certain growth factors that cause the progression of the disease. This medication works by stopping the cell growth and spreading of cancerous cells.

SIDE EFFECTS of Ponaxen 45mg tablet

  • Weight loss
  • Loss of appetite
  • Cough
  • Hair loss
  • White patches or sore lips in the mouth and throat
  • Blood in vomit
  • Red and dry eyes
  • Increased bleeding
  • Unusual bruises
  • Slow wound healing
  • Fever
  • Nausea
  • Swelling of arms and legs
  • Decreased urination
  • Sensitivity of light
  • Seizures
  • Vaginal bleeding


This medicine is prescribed by the doctor thus, follow the prescription. Ponaxen 45mg (15mg) tablets are taken orally once daily and can be taken with or without food. However, it is advisable to avoid grapefruit and its juice along with the dose.

Missed dose

It is advisable to avoid missing any doses of Ponaxen 45mg in case you miss one consult your doctor immediately.


In case of an overdose on Ponaxen, immediately contact your doctor or any healthcare provider and seek medical attention.


  • Ponaxen can cause an allergic reaction in some patients hence it becomes necessary to read the complete composition list before use.
  • Inform the doctor about all the dietary supplements, herbal medications, and prescription and non-prescription drugs. 
  • Ponaxen can decrease fertility in women. Also, it is advisable to avoid pregnancy during and till three weeks after the last dose.
  • Regular consumption of Ponaxen can increase the blood pressure.
  • Inform the doctor if you have diabetes, pancreatitis, or any bleeding problem. Also, inform if you have lactose intolerance or consume alcohol.

Q - What is Ponaxen?

Ans – Ponaxen 45mg or 15mg is an anticancer tablet that is primarily used in the treatment of leukemia.

Q - How can I take Ponaxen 45mg tablet?

Ans – Ponaxen tablets are taken orally once every day.

Q – From where can I purchase Ponaxen 45mg/15mg tablets?

Ans - Purchase Ponaxen 45mg tablets (15mg tablets) from Magicine Pharma for an affordable rate.

Q - Where to store Ponaxen 45mg tablet?

Ans - It is advisable to store the Ponaxen tablets at a place below 30°C.

Q - Can I drink alcohol with Ponaxen 45mg tablet?

Ans - Avoid drinking alcohol during the treatment with Ponaxen tablets even though no interactions of both are known.

Q - How long is the treatment with Ponaxen 45mg tablet?

Ans - The doctor decides for how long the treatment with Ponaxen will continue depending on the stage and health of the patient.

Q - Can I drive after consuming Ponaxen 45mg tablet?

Ans - It is advisable to avoid driving as Ponaxen causes dizziness as one of the side effects.

Q - Is it safe to take Ponaxen tablets during pregnancy?

Ans – Ponaxen can harm the fetus hence, it is advisable to avoid the pregnancy.

Q - What is the strength of Ponaxen?

Ans – Ponaxen tablets are available in two strengths – 45mg and 15mg.



With medicines

Ponaxen can interact with some other prescription and non-prescription medicines and affect their working thus inform the doctor if you take any of these –

  • Aspirin
  • Cabozantinib
  • Heparin
  • Ketoconazole
  • Naproxen
  • Ritonavir
  • Thalidomide
  • Warfarin

With disease

Some diseases may show interactions with Ponaxen thus, consult your doctor if you have any of these conditions –

  • Liver complications
  • Cardiovascular disorders
  • High blood pressure
  • Diabetes

With alcohol

Even though interactions of Ponaxen with alcohol are unknown it is still better to avoid its consumption.


Ponaxen 15mg /45mg tablets should not be consumed by patients who show allergic reactions to it.

Alternate Brands

  • Iclusig


Ponatinib Drug Interactions. Drugs.com. https://www.drugs.com/drug-interactions/ponatinib-index.html?filter=3

Ponatinib: MedlinePlus Drug information. https://medlineplus.gov/druginfo/meds/a613029.html

Ponatinib: Uses, interactions, mechanism of action | DrugBank Online.DrugBank. https://go.drugbank.com/drugs/DB08901

Above Content has been reviewed by Professionals