Brand Name: Teefavir
Generic Name: Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz
Dosage Form: Tablet
Composition: Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg) + Efavirenz (600mg)
Packaging: 30 tablet
Storage: Store at room temperature
Tenofovir disoproxil fumarate, Emtricitabine, and Efavirenz are active ingredients that are to prevent the multiplication of HIV (human immunodeficiency virus), and together they form a tablet known as Teefavir and these ingredients work in a combination to decrease the amount of HIV infection. This medication boosts your immune system to fight against HIV and manage AIDS (Acquired immunodeficiency syndrome). Do not stop the dosage of Teefavir tablets without taking permission from your physician.
Tenofovir Disoproxil Fumarate (Teefavir):- This is particularly a nucleoside (acyclic) phosphonate diester analog of adenosine monophosphate. It usually requires initial diester hydrolysis in order to convert it to tenofovir and subsequent phosphorylations through cellular enzymes and form tenofovir diphosphate. It works to inhibit the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination.
Emtricitabine (Teefavir):- It is a synthetic nucleoside analog of cytidine. This compound is phosphorylated by cellular enzymes for the formation of emtricitabine 5'-triphosphate. Emtricitabine works to inhibit the activity of the HIV-1 reverse transcriptase (RT) through competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporating it into nascent viral DNA resulting in chain termination. The compound is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma.
Efavirenz (Teefavir):- It is an oral non-nucleoside reverse transcriptase inhibitor. This compound is a synthetic purine derivative. It is similar to zidovudine stavudine. It was originally approved to treat HIV infections and AIDS in patients who failed therapy with zidovudine.
Teefavir (Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz) is an anti-HIV tablet, which is used for the treatment of HIV infection and to stop the infection from multiplying. It is advisable to take this medicine as prescribed by your medical practitioner and do not skip your regular dosing schedule. It is necessary to inform your doctor if you have a history of cardiac disease or liver disease. The recommended dose of Teefavir tablet is decided by your healthcare professional. Dosage may vary differently to the patients according to their age, weight, and other health concerns.
Teefavir (Tenofovir disoproxil fumarate + Emtricitabine + Efavirenz) tablets may cause certain side effects. Make sure to inform a qualified healthcare professional about the same and know the ways to manage them.
Common side effects
Redness of skin
Blood in urine
Note - consult your pharmacist or healthcare professional if any possible side effects occur.
Take the Teefavir tablets exactly as prescribed by a qualified doctor. Do not crush or chew the tablet. Be sure to avoid skipping a dose.
If you miss a dose, consult a medical practitioner. Do not increase the strength of the next dose to cope.
In case of overdose, be sure to consult a healthcare professional or a medical helpline for proper monitoring.
Tell your healthcare professional about the medicines you take before consuming Teefavir tablets.
If you are suffering from liver or/and kidney disease, avoid the consumption of Teefavir tablets, until your healthcare provider prescribes.
Warnings for female
Teefavir tablet should be used with caution in some patients because it may increase the risk of CNS side effects like drowsiness, hallucinations, etc.
Know about the risks and benefits of taking Teefavir tablets before their consumption.
If side effects last longer than usual, inform your doctor about the same and know the ways to manage them.
Use proper contraceptive measures in order to avoid pregnancy during the course of this medicine.
Q1. What is the use of teefavir 300mg tablet?
Ans. The teefavir 300mg tablet is used for treating HIV infection single or in combination with other HIV medicines.
Q2. How should you take teefavir 300mg tablets?
Ans. The teefavir 300mg tablets can be taken with a meal or snack. If prescribed another combination version of this medicine, should be taken one or two hours before a meal.
Q3. What are the precautions to be taken for teefavir 300mg tablets?
Ans. The teefavir 300mg tablets should not be taken by pregnant women, only when highly needed. It is advisable not to miss your dose until your doctor informs you.
Q4. Can I consume alcohol while taking teefavir 300mg tablets?
Ans. You should avoid consuming alcohol while taking teefavir 300mg tablets as it may damage your liver. Although, HIV medicines don’t get affected by it, always consult your doctor beforehand.
Q5. What is the strength of teefavir 300mg tablets?
Ans. The available strength of teefavir 300mg is 300mg/200mg/600mg.
Q6. How to store teefavir 300mg tablets?
Ans. The teefavir 300mg is to be stored at room temperature (below 30° C).
Q7. What are the side effects of teefavir 300mg tablets?
Ans. The common side effects of teefavir 300mg tablets are headache, nausea, stomach pain, fatigue, diarrhea, and rashes.
Q8. How do teefavir 300mg tablets work?
Ans. The teefavir 300mg tablets help in decreasing the amount of HIV in your body and boost your immunity against it.
Q9. What activities you can or can’t do after taking teefavir 300mg tablets?
Ans. You can do exercise after taking teefavir 300mg tablets. It’s not safe to drive after taking these tablets.
Q10. What to do if you miss a dose of teefavir 300mg tablets?
Ans. If you ever miss a dose of teefavir 300mg tablets, then take it as soon as possible. Don’t take a double dosage at the same time.
Teefavir tablets may interact with other medicines, diseases, and other elements. It is important to know the same before starting the course of this medicine.
- Hepatic impairment
- CNS orders
- Renal dysfunction
- Increase in cholesterol levels
Teefavir may or may not interact with alcohol. Please consult a qualified doctor before consuming alcohol.
- This medication is not recommended for use in patients suffering from kidney impairment.
- Do not administer Teefavir tablets if you have an allergy to Tenofovir disoproxil fumarate, Emtricitabine, and Efavirenz.
- Teefavir tablets are not indicated for use in patients suffering from hypersensitivity.
Efavirenz, emtricitabine, and tenofovir: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a616048.html
Tenofovir: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB14126