Mfd. by :- Pfizer (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name: Xeljanz
Generic Name: Tofacitinib
Manufacturer: Pfizer
Dosage Form: Tablet
Strength: 5mg, 10mg, 11mg, and 22mg.
Composition: Tofacitinib
Packaging: 60 tablets
Indication: Rheumatology
Storage: Store at room temperature
Xeljanz 5mg (Tofacitinib) tablet is used in the treatment of Rheumatoid arthritis. It belongs to a class of medications known as immunomodulators. This medicine works by blocking the action of the enzyme, Janus kinase. It helps to decrease joint damage in rheumatoid arthritis. It is important to take Xeljanz 5mg tablets as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Xeljanz medicine is decided by a doctor according to your previous medical condition and response to the treatment. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.
Tofacitinib targets inflammation present in rheumatoid arthritis by inhibiting the Janus kinases involved in the inflammatory response pathway. Treatment with Tofacitinib was associated with dose-dependent increases in B cell counts. Changes in circulating T-lymphocyte counts and T-lymphocyte subsets (CD3+, CD4+, and CD8+) were small and inconsistent. After treatment with Tofacitinib in patients with rheumatoid arthritis, rapid decreases in serum C-reactive protein (CRP) were observed and maintained throughout dosing.
This medicine is used to treat certain types of arthritis (Psoriatic Arthritis, Rheumatoid Arthritis, and polyarticular course juvenile idiopathic arthritis-pcJIA). Xeljanz tablets also help to block a certain enzyme in the body that affects the immune system. Take this tablet orally once a day with or without food. Do not take Xeljanz tablets in the wrong way as it may lead to some severe side effects. Regular monitoring of blood cell count, liver function, kidney function, and cholesterol levels is required during treatment with this medicine. Do not use Xeljanz 5mg Tablet (Tofacitinib) medicine if you are pregnant.
Xeljanz 5mg Tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Adalimumab
Cisplatin
Etoposide
Fluconazole
Lonafarnib
Mitotane
Hepatitis B
Viral reactivation
Tuberculosis
Infections
Renal disease
Hepatic Impairment
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Do not take this medicine if you are allergic to Tofacitinib.
Xeljanz (Tofacitinib) medicine is not recommended in patients known to be hypersensitive.
This medicine may cause some major and minor side effects. Discuss the risks and benefits of the Xeljanz tablets with the doctor before starting the treatment.
Bladder pain
Irregular heartbeat
Bloating
Diarrhea
Chills
Runny or stuffy nose
Nausea
Unusual tiredness
Headache
Dizziness
Fever
Sore throat
Weight loss
Chest pain
Ear congestion
Back pain
Inflammation of the throat and the nasal passage
Upper respiratory tract infection
Allergic reaction
Unusual weakness
Shortness of breath
Muscle pain
Pounding in the ears
Swollen glands
Decreased urination
Fainting
Rash
Vomiting
Sunken eyes
Tingling of the hands or feet
Note - immediately contact your health care provider if any side effects occur.
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
It is advisable not to miss a dose. If you miss a scheduled dose of Xeljanz tablets, contact your doctor immediately.
In case of an overdose of Xeljanz tablets, the doctor will provide emergency medical treatment.
Before starting treatment with Xeljanz 5mg Tablet medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Contraception
Use suitable methods of contraception to prevent pregnancy while taking Xeljanz 5mg Tablet medicine.
Children and adolescents
Xeljanz Tablets are not recommended for use in children under 18 years of age.
Pregnancy
Do not use Xeljanz 5mg Tablet medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
Breastfeeding
This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Xeljanz 5mg (Tofacitinib).
This medicine may affect the immune system and may increase the risk of developing infections.
Xeljanz tablets may increase the levels of cholesterol and low-density lipoprotein cholesterol.
Inform your doctor if you experience any side effects like - dizziness, nausea, abdominal pain, increased appetite, and vomiting.
Close monitoring of liver and kidney function is required during treatment with this medicine.
This medicine may increase the risk of non-melanoma skin cancer.
Do not drive or operate heavy machinery.
Do not crush or break the tablet.
Not safe for pregnant women.
Do not breastfeed while receiving this medication.
Ans. This medicine is used in the treatment of Rheumatoid arthritis. It helps to block a certain enzyme in the body that affects the immune system.
Ans. This medicine is available in the strength of 5mg, 10mg, 11mg, and 22mg.
Ans. Some common side effects are - bladder pain, constipation, insomnia, sore throat, dizziness, fatigue, nausea, fever, etc.
Ans. If you miss a scheduled dose of Xeljanz tablets, contact your doctor immediately.
Ans. This medicine works by blocking the action of the enzyme, Janus kinase. It helps to decrease joint damage in rheumatoid arthritis.
Ans. This medicine is not recommended during pregnancy.
Ans. Follow your doctor’s advice about any restrictions on food and other activities.
Ans. It is important to take this medicine as prescribed by your doctor.
Ans. This medicine may affect your vision and your ability to concentrate.
Ans. Please consult your doctor before consuming this drug.
Ans. Store this medicine at room temperature.
Ans. This medicine is not recommended in breastfeeding unless it is necessary.
Ans. Please consult your doctor before consuming alcohol.