Xtane 25mg Tablet

Xtane 25mg Tablet

Prescription requiredRx Required

Salt Composition: Exemestane

Expiry Date: 01/2028

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30 Tablets

About The Product

Breast Cancer

Xtane 25 mg Tablet comprises Exemestane (an aromatase inhibitor). This medicine is prescribed for the treatment of hormone-dependent breast cancer among postmenopausal women. The medication works to reduce the estrogen levels, thus hindering the proliferation of cancer cells.

Xtane is used in early breast cancer after 2–3 years of treatment with tamoxifen and in advanced breast cancer that has not responded to other hormonal treatments. It is usually taken once a day after a meal and can have side effects such as insomnia, headache, sweating, joint or bone pain, fatigue, and nausea.

This is unsafe during pregnancy or breastfeeding and may decrease bone density, so close monitoring and medical guidance are essential, especially in patients with liver or kidney problems.

Uses

  • ​Early Breast Cancer Treatment
  • Advanced Breast Cancer Treatment

Side Effects

Side effects are unwanted symptoms that can occur from any medical treatment. Like other medications, the Xtane 25mg Tablet can also have adverse effects on the body, most of which resolve without the need for medical attention. In in case of any unusual or severe side effects, immediately.

Some common side effects include:

  • Headache
  • Dizziness
  • Rash
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Insomnia (difficulty sleeping)
  • Fatigue / Weakness
  • Increased sweating
  • Hot flushes
  • Depression
  • Muscle pain / Joint pain / Back pain
  • Bone pain / Fracture / Osteoporosis
  • Carpal tunnel syndrome (numbness, tingling, hand pain)
  • Paresthesia (tingling or pricking sensation)
  • Itching (pruritus) / Urticaria
  • Hair loss
  • Decreased appetite / Increased appetite
  • Peripheral edema (swelling in hands and feet)
  • Allergic reactions / Difficulty breathing
  • Low white blood cell count (lymphocytes, leukopenia)
  • Low blood platelets (thrombocytopenia)
  • High liver enzyme levels

How To Use

  • Doctor determines the exact dose and duration with Xtane 25mg Tablet as per the overall health condition of the patient.
  • This tablet should be taken with food or after food, but at the fixed time every day to get effective results.
  • Swallow it as a whole with a glass of water and do not crush, chew, or open it.

How It Works

  • Xtane 25mg Tablet is an anticancer medicine with Exemestane as an active ingredient.
  • It belongs to the class of drugs known as aromatase inhibitors.
  • Exemestane works by blocking the action of the enzyme responsible for the production of the female hormone estrogen to lower its amount in the body.
  • It results in controlling the growth of cancer cells as some breast cancer cells require estrogen to multiply.

Safety Advice

Alcohol
It is unclear whether drinking alcohol while taking Xtane tablets is safe. To stay protected, you should discuss alcohol use with your doctor, who can guide you based on your health condition.
Pregnancy
Xtane Tablet should never be used during pregnancy, as it can cause serious harm to the unborn child, including birth defects or pregnancy loss. Women who are pregnant or planning to become pregnant must avoid this medicine completely.
Breast Feeding
Xtane Tablet should never be used during breastfeeding, as it can cause serious harm to the newborn child.
Driving
Xtane 25mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.
Kidney
Share your medical history with the doctor before starting the Xtane 25mg Tablet. Do not take it without consulting a doctor if you have any kidney related issue.
Liver
Consumption of Xtane 25mg Tablet should be avoided without informing the doctor if you have any liver-related issues.

Missed Doses

  • If you forget to take a dose of Xtane 25mg Tablet, consult your doctor.
  • Don’t double up the next dose to cope with the missed one unless your doctor recommends it.​

FAQs

Xtane 25mg is a prescription-based anticancer medicine used in the treatment of hormone-receptor-positive early and advanced breast cancer in women who have gone through menopause.


References

  • Coombes, R. C., Hall, E., Gibson, L. J., Paridaens, R., Jassem, J., Delozier, T., ... & Bliss, J. M. (2004). A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. New England Journal of Medicine, 350(11), 1081-1092. https://pubmed.ncbi.nlm.nih.gov/15014181/
  • Coleman, R. E., Banks, L. M., Girgis, S. I., Kilburn, L. S., Vrdoljak, E., Fox, J., ... & Coombes, R. C. (2007). Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES): a randomised controlled study. The lancet oncology, 8(2), 119-127. https://pubmed.ncbi.nlm.nih.gov/17267326/
  • Pagani, O., Regan, M. M., Walley, B. A., Fleming, G. F., Colleoni, M., Láng, I., ... & Francis, P. A. (2014). Adjuvant exemestane with ovarian suppression in premenopausal breast cancer. New England Journal of Medicine, 371(2), 107-118. https://pubmed.ncbi.nlm.nih.gov/24881463/
  • Deeks, E. D., & Scott, L. J. (2009). Exemestane: a review of its use in postmenopausal women with breast cancer. Drugs, 69(7), 889-918. https://pubmed.ncbi.nlm.nih.gov/19441873/
  • Goss, P. E., Ingle, J. N., Alés-Martínez, J. E., Cheung, A. M., Chlebowski, R. T., Wactawski-Wende, J., ... & Richardson, H. (2011). Exemestane for breast-cancer prevention in postmenopausal women. New England Journal of Medicine, 364(25), 2381-2391. https://pubmed.ncbi.nlm.nih.gov/21639806/

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