Hepatitis B infection is a viral infection that especially targets the liver in the body. Its long term impact causes liver cancer and cirrhosis. It is mainly classified into Acute and Chronic infection based on the persistence of virus in the body. For now, there is no preventive vaccination or precised medication available for the treatment of this infection. But, Chemotherapy is the best widely accepted treatment option in case of Hepatitis B to manage its symptoms and regain the immunity.
Let us get some insights on the statistics, causes,diagnostic and treatment of Hepatitis B. Let us also understand with short details about the doctor's prescribed medication for hepatitis B infection that include Entehep 0.5mg Tablet, TENVIR 300mg, Entaliv 0.5mg Tablet, Entavir 0.5mg Tablet, x-vir 0.5mg Tablet and Hepbest 25mg Tablet , in order to understand the functioning as well as effectiveness of chemotherapy in its treatment.
Worldwide Prevalence and Statistics
World Health Organization(WHO) states that 254 million people were living with Chronic Hepatitis B infection in year 2022, with 1.2 million new infections each year. In 2022, Hepatitis B caused around 1.1 million deaths mainly due to liver cancer and cirrhosis. Experts assume this number to rise based on the current global scenario.
Major Causes and Risk Categories
The Hepatitis B Virus causes hepatitis B infection. It is a viral attack that impacts the liver in the body and does not include any genetic mutations before hand in the body. Following is the list of causes and transmission ways that lead to hepatitis B infection:
● Mother to Child
● Sharing Belongings
● Sexual Contact
● Infected Blood Transfusion
● Sharing infected syringe
In particular, various category of people are at a higher risk of getting infection as compared to other. Following is the list of risk categories:
● Developing Fetus whose mother is Hepatitis B infected
● Multiple Sexual Partners
● Partners doing Unprotected Sex
● Drugs Addict
● Men to Men Intimacy
● HemoDialysis Patients
● Healthcare Workers
Key Symptoms to Watch Out For
Symptoms mainly arise after one to four months of infection and can last for multiple weeks.Following is the list of key symptoms to watch out for:
● Fever
● Fatigue
● Loss of appetite
● Abdominal pain
● Nausea
● Joint Pain
● Jaundice
● Dark urine
● Clay Colored Stools
How HBV Is Diagnosed
HBV Diagnosis follows two staged approach. It comprises of a series of blood tests and then imaging.Following are the types of test used to diagnose HBV:
- Blood Tests: Blood sample are analyzed based on three further sub categories to detect the presence of infection.
● Hepatitis B surface antigen (HBsAg): It is a protein present on the surface of HBV. Positive results means presence of virus.
● Hepatitis B surface antibody (Anti-HBs): It is a antibody that is produced by body against HBV. Positive results means presence of virus.
● Hepatitis B core antibody (Anti-HBc): Antibody to the core protein of HBV that appears on onset of infection. Positive results means past or present presence of HBV.
- Imaging Tests: It include certain testsof liver to detect the extent of infection in the body.
● Liver Ultrasound: It is a non invasive, painless and essential image technique to monitor progression of infection at regular intervals.It tracks change in liver size along with its stiffness.
● Liver Biopsy: It is a invasive technique that uses biopsy needle to to retrieve liver tissue sample. As a result it helps to assess the degree of inflammation and staging in chronic infection.
● FibroScan: It is a non invasive technique that uses certain range of vibration on skin , and measures the velocity of shear waves travelling though liver. Its higher value in kilo pascals indicate more stiffness. Normal liver fibroscan rangeis 2-7 kPa
Acute vs. Chronic Hepatitis B
This classification is based on the time span of infection that for how long it persists in the body. Following is the table to show the difference between the two types:
Acute Hepatitis B Infection | Chronic Hepatitis B Infection |
Short Term : Usually lasts for less than six months. | Long Term: Lasts for about six months and can persists lifelong. |
Low in Adults | High in Newborn and Young Children |
Common and Mild symptoms. For example, fever, fatigue, nausea etc. | Asymptomatic in most of the cases until serious disease develops. |
Supportive care, No specific antiviral medication | Lifelong antiviral medication along with supportive care |
Key Phrases and Time Frames of Hepatitis B Infection
The normal time of hepatitis b infection ranges from 30-180 days. Starting from pathogen exposure to symptoms appearance. Following are the key phrases of hepatitis B infection:
- Incubation Period: It refers to the development phase of the virus from its entry to showing symptoms in the body. It is usually around 30-180 days. The virus is detectable within 60-90 days but shows symptoms later.
- Prodromal Phase: The common symptoms such as fever, weakness , nausea arise at this period of time. It is usually lasts around3-10 days before the appearance of jaundice.
- Icteric Phase: It refers to the jaundice phase of infection along with liver tenderness. It lasts around 1-3 weeks.
- Convalescent Phase: It is a recovery as well as persistence phase of the body. It lasts for around several weeks to months.
- Chronic Hepatitis B: If post these phases body fails to get rid of virus especially in young children and infants, Chronic infection starts that lasts for years or lifelong.
Most Effective Treatment Options
The most effective treatment option for acute HBV is supportive care. It includes proper diet, regular exercise and Post-exposure prophylaxis injections especially meant of healthcare provider. This injection is administered within 24 hours of accidental exposure to infection via infected needle or syringe. On the other hand doctor prescribe effective antiviral medication that aims to target the internal mechanism of HBV that promotes its death. It is generally prescribed in the case of Chronic Hepatitis B infection.
Following are some of the Antiviral Medication with its details and mechanism of action:
1. Entehep 0.5mg Tablet:
Entehep 0.5mg Tablet is a antiviral medication that contains Entecavir salt, used to treat Hepatitis B Infection. It targets the viral replication machinery to stop further spreading of virus in the body. This medication mainly blocks the DNA polymerase of virus that inhibits virus replication. As a result, infection is controlled and managed.
Entehep 0.5mg is available in the form of tablet on the market. Therefore it is advice to swallow the tablet directly with the help of water. Avoid breaking, chewing or biting of tablet for effective results.
Entehep 0.5mg price vary widely on multiple platforms. To get the best price, visit Magicine Pharma. It provides global delivery from trusted sources.
2. TENVIR 300mg:
TENVIR 300mg Tablets are antiviral in nature that works against the virus. Doctor recommends it to treat Hepatitis B Infection as well as HIV-1 Infection. It contains tenofovir disoproxil fumarate salt that belongs to class of nucleotide reverse transcriptase inhibitor (NRTI). This NRTI blocks the DNA Polymerase enzyme used by HBV and reverse transcriptase enzyme used by HIV to inhibit further viral replication.
TENVIR 300mg is available in the form of tablet on the market. Therefore it is advice to swallow the tablet directly with the help of water. Avoid breaking, chewing or biting of tablet for effective results.
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3. Entaliv 0.5mg Tablet:
Entaliv 0.5mg Tablet is a antiviral , Entecavir chemical salt based medicine that blocks the DNA Polymerase of virus to inhibit virus from growing and multiplying.
Entaliv 0.5mg is a tablet and is supposed to be swallowed as whole with help of water on set time by doctor.
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4. Entavir 0.5mg Tablet:
Entavir 0.5mg Tablet is a medication used against HBV for adults or children aged 2 years or above. It blocks DNA Polymerase to inhibits virus from replicating. It also improves liver functions.
Entavir 0.5mgis a tablet and is supposed to be swallowed as whole with help of water on set time by doctor daily. Avoid missing dose for effective results.
To get huge discounts and deals on Entavir 0.5mg price, visit Magicine Pharma. It offers fast delivery from trusted sources in multiple countries.
5. X-vir 0.5mg Tablet :
X-vir 0.5mg Tablet is a Entecavir salt based antiviral medication that blocks the basic cellular machinery of virus replication. It blocks the DNA Polymerase that further inhibits its replication. Doctor prescribe this medication against HBV for adults or children aged 2 years or above.
X-vir 0.5mg is available in the form of tablet on the market. Therefore it is advice to swallow the tablet directly with the help of water. Avoid breaking, chewing or biting of tablet for effective results. X-vir 0.5mg price vary widely on multiple platforms. To get the best price, visit Magicine Pharma. It provides global delivery from trusted sources.
5.Hepbest 25mg Tablet:
Hepbest 25mg Tablet is a antiviral medication that contains tenofovir alafenamide (TAF). It is a pro drug and is, therefore, inactive before entering the body. It then converts to tenofovir that blocks DNA Polymerase and inhibits further replication and growth.
Hepbest 25mg is a tablet and is supposed to be swallowed as whole with help of water on set time by doctor daily. Avoid missing dose for effective results.
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Supportive Care for Hepatitis B Treatment
These supportive care tips help in managing the symptoms, protecting liver health and preventing any further complications. It is particular to acute infections and for those with mild symptoms that dont require antiviral medication.Following is the list of supportive care tips that help in the treatment:
● Intake of Balanced Diet
● Enough Sleep and Rest
● Avoid Substance Abuse
● Regular Medical Check ups
● Vaccinations
● Proper Awareness
● Emotional Support
Preventive Measures and Vaccination Importance
Following are the preventive tips to avoid getting HBV infection:
● No Multiple Partner Sex
● Use Protection
● Know about Parents' Medical History
● Avoid using the same syringe
● Regular checkups
Vaccination is crucial due to the following points:
● Prevent Serious Life Threat
● To Beat Chronic Infection
● Long Term Protection
● Cost Effectiveness
Myths and Facts About Hepatitis B
Following is the list of myths along with its facts about HBV.
Myths | Facts |
Spread through casual contact like shaking hands etc. | False, its spread through blood, semen and body fluid transmission. |
Hepatitis B is a genetic infection. | False, Its a viral infection that is acquired from the environment. |
It shows multiple symptoms. | False, It is mostly asymptomatic, shows mild symptoms in acute infection cases. |
There is no treatment of infection. | False, Though there is no complete cure, antiviral medication is an effective treatment to manage symptoms and serious diseases. |
Conclusion
In conclusion, a chronic Hepatitis B infection poses a major risk to one's life. There is no remedy for it. However, doctors prescribe antiviral drugs that work well and contain a family of chemical salt that cause the body's internal machinery to break down. Thus, control symptoms and stop the illness from getting worse. Entehep 0.5mg Tablet, TENVIR 300mg, Entaliv 0.5mg Tablet, Entavir 0.5mg Tablet, x-vir 0.5mg Tablet and Hepbest 25mg Tablet are Hepatitis B Treatment worldwide. Magicine Pharma provides reasonable amount and great deals and discounts on these medication pricing. It offers pan global delivery from verified and trusted sources for effective, timely and smooth handling to customer as well as consumer. Furthermore, Acute infections that are treatable and only last a brief time are treated with a variety of supportive care techniques. The duration of a hepatitis B infection can range from 30 to 180 days from the moment of virus introduction until symptoms appear. Adolescents, adults between the ages of 19 and 59, and newborns should all receive the appropriate universal preventive vaccine against Hepatitis B infection in order to avoid infection. This all together also highlights the myths people hear about this infection along with its well labeled fact.
FAQs
1. Is it safe to breast feed a baby?
A-Yes, its safe to breast feed a baby if mother is HBV positive, especially if the newborn receives proper immunoprophylaxis at birth. As infection is not transferred via breast milk.
2. Is Hepatitis B completely curable?
A-No, it is not completely curable but it can only be managed or treated with effective medication.
3. Is there any Preventive vaccine against hepatitis B infection?
A-Yes, there is a universal preventive vaccine against hepatitis B infection that should be administered timely to infant, adolescent and adult.
References:
https://my.clevelandclinic.org/health/diseases/4246-hepatitis-b
https://www.mayoclinic.org/diseases-conditions/hepatitis-b/symptoms-causes/syc-20366802
https://www.who.int/news-room/fact-sheets/detail/hepatitis-b
https://www.cdc.gov/hepatitis-b/index.html
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