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Natco
30 Capsule
Lenalidomide
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Overview
Lenalid 25mg Capsule is an anti-cancer medication. It is used for the treatment of myelodysplastic syndrome and multiple myeloma. Lenalid 25mg Capsule affects the functioning of the immune system in producing more RBCs in the bone marrow, reducing the need for blood transfusions and making the patient feel better. This medicine can be taken with or without food, but it must be taken at the same time every day regularly to increase the effectiveness of the medicine. It is important to monitor and check up on your health to prevent getting sick. Lenalid 25mg Capsule restricts the production and growth of chemical messengers, thereby stopping or slowing the growth of cancer cells in the human body.
Blood Cell Cancers, Leukemia
Multiple myeloma
Treatment of Myelodysplastic Syndrome
The human body reacts differently to Lenalid 25mg Capsule. Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately. Some of the common side effects of Lenalid 25mg Capsule are mentioned below: Sleepiness
Confusion
Tremor
Swelling
Respiratory disorder
Bleeding gums
Blood clots
Anxiety
Muscle pain
Dry skin
Constipation
Rash
Cough
Nausea
Sore throat
Take the dose of Lenalid 25mg Capsule as per your healthcare provider’s prescription. Do not stop taking the medicine suddenly, unless your doctor tells you. This medicine is given under the strict supervision of a doctor. Do not self-administer. Overdose is a very unusual state for this medicine because it is given under the supervision of a healthcare provider. Lenalid 25mg Capsule can be taken without food or with food. The doctor will provide emergency medical treatment. You should not break, crush, or chew the medicine; it should be swallowed as a whole.
Lenalidomide Capsules are a thalidomide analog. It is an immunomodulatory agent. This compound possesses immunomodulatory and antiangiogenic properties. It works to inhibit the secretion of pro-inflammatory cytokines and increases the secretion of anti-inflammatory cytokines from peripheral blood mononuclear cells. Lenalidomide works to inhibit cell proliferation with varying effectiveness (IC50s) in some but not all cell lines. It prevents the growth of new blood vessels within the tumor.

Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Lenalidomide Capsules. Consult your doctor for further information.

Pregnancy
consult your doctor
Lenalidomide Capsules may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking Lenalidomide Capsules during pregnancy has shown harmful effects on the developing baby.

Breast Feeding
consult your doctor
Lenalidomide Capsules is probably not safe if you're breastfeeding. Kindly consult your doctor before taking Lenalidomide Capsules while breastfeeding, as there are chances that it may pass to the developing baby through the breast milk of the mother.

Driving
unsafe
It is advisable not to drive or operate heavy machinery after taking Lenalidomide Capsules, as you may feel dizzy.

Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Lenalidomide Capsules. Patients with renal impairment must be careful while taking Lenalidomide Capsules. They may require adjustment in the dose.

Liver
safe if prescribed
Inform your doctor before starting Lenalidomide Capsules if you have liver disease to avoid any serious side effects. Patients with hepatic impairment must be careful while taking Lenalidomide Capsules. They may require adjustment in the dose.
It is advised not to miss any scheduled dosage of Lenalid 25mg capsule. In case you miss a dose, consult your doctor immediately. Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Take blood tests to monitor signs of blood clots or a fall in blood cell count on a regular basis.
Intake a lot of water and fluids to keep the body hydrated. Taking the Lenalid 25mg capsule may cause dehydration.
Avoid activity that results in bruising or blood loss, and avoid contact with people who have colds.
Inform your healthcare expert that you're taking the Lenalid 25mg capsule if you're undergoing any emergency surgery.
Use effective birth control methods to avoid pregnancy for 4 months before and after taking Lenalid 25mg capsule. It may affect the unborn baby and can cause rare birth abnormalities.
Lenalidomide 10mg capsule is an anti-cancer medication, prescribed for the treatment of Multiple Myeloma and Lepra Reactions.
The side effects of Lidmed (Lenalidomide 10 mg capsules) are fever, nausea, chills, skin rash, itching, vomiting, swelling on the face, diarrhea, anemia, etc. Also, other side effects may occur. Therefore, make sure to call your healthcare provider if the condition worsens.
Lenalidomide 10mg capsule should be swallowed with water. It should not be crushed, chewed, or cut. Also, a scheduled dose should not be missed.
Store Lenalidomide 10mg capsule at room temperature (10-30°C).
Lenalidomide capsules are available in strengths of 10 mg and 25 mg. It is available in the form of capsules for oral administration.
Memory impairments have been reported in a few patients. Consult your doctor if you face problems with concentration, loss of memory, or are confused after taking Lenalidomide 10 mg capsules.
Time and dose are decided by your doctor. Lenalidomide 10 mg capsules should be taken at the same time, usually with a meal and a large glass of water to avoid stomach problems.
No, children below 18 years of age are not advised to take Lenalidomide 10 mg capsules, as it results in severe complications.
Your doctor decides the doses and duration of taking Lenalidomide 10 mg capsules. It is advised not to crush, chew, or break it, just swallow the whole tablet with water.
Yes, Lenalidomide 10 mg capsules are given to dialysis patients after dialysis is done. However, the doctor may adjust the dose if needed according to the patients being treated.
people with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) or other cancer, undergoing chemotherapy and a blood stem cell transplant with the addition of Lenalidomide 10 mg capsules have a higher risk of geting new cancers like a type of lymphoma called Hodgkin lymphoma and certain blood cancers (acute myelogenous leukemia or AML). Consult your doctor to know the possible risks of these medicines.
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Eisen T, Trefzer U, Hamilton A, Hersey P, Millward M, Knight RD, Jungnelius JU, Glaspy J. Results of a multicenter, randomized, double-blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma. Cancer. 116(1):146-54.
Glaspy J, Atkins MB, Richards JM, Agarwala SS, O'Day S, Knight RD, Jungnelius JU, Bedikian AY. Results of a multicenter, randomized, double-blind, dose-evaluating phase 2/3 study of lenalidomide in the treatment of metastatic malignant melanoma. Cancer. 115(22):5228-36.
List A, Kurtin S, Roe DJ, Buresh A, Mahadevan D, Fuchs D, Rimsza L, Heaton R, Knight R, Zeldis JB. (2024). Efficacy of lenalidomide in myelodysplastic syndromes. N Engl J Med. 352(6):549-57.
Shen Q, Gao T, Xiang J, Feng P, Liu X, Zheng L. (2024).Pharmacokinetic and bioequivalence of lenalidomide in multiple myeloma patients. Int J Clin Pharmacol Ther. 61(4):181-188
Suzuki K, Shinagawa A, Uchida T, Taniwaki M, Hirata H, Ishizawa K, Matsue K, Ogawa Y, Shimizu T, Otsuka M, Matsumoto M, Iida S, Terui Y, Matsumura I, Ikeda T, Takezako N, Ogaki Y, Midorikawa S, Houck V, Ervin-Haynes A, Chou T. (2024). Lenalidomide and low-dose dexamethasone in Japanese patients with newly diagnosed multiple myeloma: A phase II study. Cancer Sci. 107(5):653-8.
V. Sanchorawala et al. (2025). A phase II trial of lenalidomide for patients with AL amyloidosis. J Clin Oncol 24, 7524-7524.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.

Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.