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genentech
1 Vial
Bevacizumab
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Overview
Avastin 400mg injection belongs to the category of anticancer medicines. This medicine is primarily used to treat patients diagnosed with breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, ovarian cancer, and colorectal cancer. The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Avastin injection is typically administered in combination with another anticancer medication as part of a combination therapy to enhance the treatment's efficacy.
Colorectal cancer
Cancer of the colon and rectum
Ovarian cancer
Cervical cancer
Kidney cancer
Brain tumor
Non-small cell lung cancer
The human body shows undesired symptoms after taking the Avastin 400mg injection. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Avastin injection are mentioned below:
Fever
Fatigue
Back pain
Headache
Mouth sore
Weight loss
Constipation
Nose bleeding
Breathlessness
Taste alteration of appetite
Abdominal pain
Increased heart rate
High blood pressure
Nausea and vomiting
Numbness in hands and feet. Severe side effects:
Gut infection
Blood clotting
Hemorrhage
Protein in urine
Severe infection
Decrease in the level of white blood cells
Avastin 400mg injection is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Avastin 400mg injection. It is advised to consult your doctor for further information.
Pregnancy
consult your doctor
Avastin 400mg injection may be considered unsafe during pregnancy. Please consult your doctor in such condition.
Breast Feeding
consult your doctor
Avastin 400mg injection is probably not safe if you're breastfeeding. Kindly consult your doctor.
Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Avastin 400mg injection.
Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Avastin 400mg injection.
Liver
safe if prescribed
Inform your doctor before starting Avastin 400mg injection if you have liver disease to avoid any serious side effects.
It is advised not to miss any scheduled dosage of Avastin 400mg injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to use effective birth control methods and avoid pregnancy during the treatment with Avastin.
A person should avoid smoking while undergoing treatment with Avastin injection. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Avastin 400mg injection
Swelling of hands, lips, and weight gain are some of the side effects observed after taking Avastin. To reduce them, the doctor may suggest some medication.
Skin becomes extremely sensitive after taking the Avastin injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Avastin 400mg injection, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Avastin 400mg injection. Consult your doctor if it doesn't stop or if blood appears in your stools.
In case you notice symptoms like blurred vision, difficulty breathing, cough & fever, and diarrhea while taking Avastin injection, consult your doctor immediately before these symptoms become severe.
Taking Avastin 400mg injection can lower your ability to heal wounds rapidly. So avoid doing such activities that can lead to bruising and wounds. Inform your doctor if you are going an emergency surgical procedure.
If you experience any kind of symptoms after taking Avastin 400mg injection like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
Avastin injection can pass through the mother's blood and harm the unborn baby. So, it is advised not to give this drug to pregnant and breastfeeding women.
Avastin can treat multiple cancer variants, including breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, ovarian cancer, and colorectal cancer.
Avastin 400mg Injection is a type of recombinant monoclonal antibody that is an immunotherapy drug. It can be given alone in monotherapy or in combination with other chemotherapy or immunotherapy medications to improve treatment effectiveness.
Avastin 400mg injection is injected intravenously by an expert nurse or healthcare professional. Do not self-administer it.
Even with Avastin 400mg Injection, the doctor recommends chemotherapy to make treatment more effective and to improve the overall treatment outcome.
Taking Avastin can lower your ability to heal wounds rapidly. So avoid doing such activities that can lead to bruising and wounds. Inform your doctor if you are going on an emergency surgical procedure.
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Authors. (2024). Low‑dose bevacizumab for focal radiation necrosis of the brain: fixed 400 mg loading dose with 100 mg maintenance dosing. Journal / Case Series Platform. Gilbert, M. R., et al. (2012). A randomized trial of bevacizumab for newly diagnosed glioblastoma. New England Journal of Medicine, 367(2), 130–138.
Hurwitz, H. I., et al. (2013). Efficacy and safety of bevacizumab in metastatic colorectal cancer: pooled analysis from seven randomized controlled trials. The Oncologist, 18(9), 1004–1012.
Ledermann, J., et al. (2011). A phase III study of bevacizumab in advanced ovarian cancer. New England Journal of Medicine, 365(26), 2484–2496.
Makris, G., Kantzioura, A., Beredima, M., Karampola, M., Emmanouilides, C., et al. (2015). Feasibility of rapid infusion of the initial dose of bevacizumab in patients with cancer. Journal BUON, 20(3), 923–927.
Terazawa, T., Nishitani, H., Kato, K., Hashimoto, H., Akiyoshi, K., et al. (2014). The feasibility of a short bevacizumab infusion in patients with metastatic colorectal cancer. Anticancer Research, 34(2), 1053–1056.
Tijtgat, J., Calliauw, E., Dirven, I., Vounckx, M., Kamel, R., Vanbinst, A. M., Everaert, H., Seynaeve, L., Van Den Berge, D., Duerinck, J., & Neyns, B. (2023). Low‑Dose Bevacizumab for the Treatment of Focal Radiation Necrosis of the Brain (fRNB): A Single‑Center Case Series. Cancers (Basel), 15(9), 2560.
