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FASLODEX 250MG INJECTION

Mfd. by :- Astra Zeneca (Fulfilled By : Magicine Pharma)

Faslodex 250mg Injection

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Medicine Details     

Brand Name – Faslodex

Generic Name – Fulvestrant

Manufacturer – Astra Zeneca

Dosage – Injection / Vial

Strength – 250 mg/mL

Storage – Refrigerate (2° – 8° C)

Indication – Breast Cancer

Prescription required – Yes

Faslodex 250mg injection / Vial

Fulvestrant 250mg injection also popular by the brand name Faslodex is an anticancer medication. It is used for the treatment of Breast Cancer in post-menopausal women. Fulvestrant is an estrogen receptor antagonist and exhibits zero agonist properties. It blocks the effect of estrogen on cancerous breast cells and as a result, interferes in the growth and spreading of the tumor.

Faslodex 250mg injection or Fulvestrant vial is administered as an intramuscular injection. It is a prescription-based drug. Therefore, the dosage, and duration will be decided by the doctor. Also, inform your doctor about all your prior medical conditions and allergies.

Mechanism of Action

Faslodex 250mg injection (Fulvestrant) is used in the treatment of metastatic breast cancer which is hormone receptor-positive in post-menopausal women. It does not exhibit agonist properties but has anti-estrogen properties.  Fulvestrant is an estrogen receptor antagonist and it works by binding to the estrogen receptors of cancerous cells. As a result -

  • It blocks estrogen from binding to its own receptor.
  • It degrades the estrogen receptors to stop it from functioning again.

This decreases the levels of estrogen and therefore, reduces the growth and spreading of cancerous cells.

Contraindication

  1. Allergies – Some components of Fulvestrant 250mg vial can start an allergic reaction. Hence, it is recommended to consult your doctor and find an appropriate alternative for this medicine.
  2. Pregnancy – Fulvestrant can cause harm to the fetus hence, pregnancy should be avoided
  3. Breastfeeding – Fulvestrant 250mg can pass through the milk thus, it is advised to stop breastfeeding during the treatment.
  4. Pediatrics - Fulvestrant injection should not be given to children below 18.

 

Side Effects of Faslodex 250 mg injection

Some of the common side effects of Faslodex 250 mg injection (Fulvestrant ) which do not require medical attention unless the symptoms worsen –

  1. Diarrhea
  2. Nausea
  3. Vomiting
  4. Constipation
  5. Headache
  6. Upset stomach
  7. Fatigue
  8. Loss in appetite
  9. Excessive sweating
  10. Sleeping problems
  11. Bones, joint, back pain
  12. Hair loss (in some cases when used in combination with other medicines)

Side effects that require immediate medical care –

  1. Trouble in breathing
  2. Rashes, swelling, and redness of the injection site
  3. Yellowing of eye and skin
  4. Increased bleeding or bruising
  5. Vaginal bleeding
  6. Painful urination
  7. Chest pain
  8. Irregular heart rate
  9. Blurred vision

Dosage

Faslodex 250mg (Fulvestrant ) is given as an intramuscular injection in both bollocks. It should not be self-administered.

Missed dosage

In case of a missed dosage, it is advised to consult your doctor or healthcare provider and book the next schedule immediately.

Storage

Not applicable for Fulvestrant (Faslodex 250mg). This medicine should be administered by a doctor. Hence, should not be stored at home.

Overdose  

If you experience any signs of overdose, call your doctor or emergency helpline immediately.

Warnings

  1. Some ingredients of the Faslodex 250mg injection (Fulvestrant) can cause an allergic reaction. Redness, rashes, and swelling of the skin around the injection site are the initial signs of an allergy. Contact your doctor if you observe any of these signs.
  2. Faslodex can interact with other medications and supplements which can interfere with its working. Especially blood thinners.
  3. Faslodex 250mg injection (Fulvestrant) can harm the fetus. So, it is recommended to avoid pregnancy and breastfeeding during the course of treatment.
  4. Avoid taking alcohol during the treatment.
  5. Avoid driving or using heavy machinery.
  6. Discuss with your doctor in case you are having some other surgery.
  7. Consult your doctor if you have already had the following-
  • Liver disease
  • Bleeding complications
  • Low platelet count

FAQ Related to Faslodex 250 mg injection

  • What is Faslodex used for?

Faslodex 250 mg injection (Fulvestrant ) is used in the treatment of advanced metastatic breast cancer (hormone receptor-positive) in post-menopausal women.

  • How can I take a Faslodex injection?

Therefore, Faslodex 250 mg injection (Fulvestrant) should not be self-administered and should be strictly administered by doctors only.

  • For how long should I take Faslodex injections?

Faslodex 250 mg injection (Fulvestrant) is a prescription-based medicine. In Addition, the course of the medicine will be decided by your doctor depending on the condition and stage of cancer.

  • Is it safe to drive after taking Faslodex?

It is not advised to drive after injecting Faslodex as it may cause dizziness as a side effect.

  • Can children take Faslodex?

Faslodex 250 mg injection is not meant for children below the age of 18.

  • Can I drink alcohol during the treatment?

Scientifically there have been no interactions found between alcohol and Fulvestrant (Faslodex 250 mg injection). However, it is still recommended to avoid alcohol during the treatment.

Interactions

It is recommended to inform your doctor about all the medications and supplements you take.

With Alcohol

Interactions of Faslodex with alcohol are known. However, it is advisable to avoid alcohol as it may cause dizziness.

With other medications

  1. Omacetaxine
  2. Fluoroestradiol

Other brand names

  1. Fulvant
  2. Fasnorm
  3. Fulviglen
  4. Faslomax
  5. Fuvestrol
  6. Strantas

Reference

  • Fulvestrant: Drugs information and usage are available at: - https://go.drugbank.com/drugs/DB00947 and https://pubchem.ncbi.nlm.nih.gov/compound/Fulvestrant.

Fulvestrant: Mechanism, side effects, and dosage are available at: - https://www.cancerresearchuk.org/about-cancer/treatment/drugs/fulvestrant-faslodex, https://www.drugs.com/fulvestrant.html, and https://www.webmd.com/drugs/2/drug-63182/fulvestrant-intramuscular/details

Above Content has been reviewed by Professionals