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1 Ampule
Calcium Leucovorin
Keep in cold place
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Overview
Leucowel 15mg/2ml Injection belongs to the category of folic acid analogs. This medicine is primarily used to reduce the harmful side effects of methotrexate. It performs multiple functions like acting as an immunosuppressant, treating anemia, and is given to patients who have accidentally taken an overdose of methotrexate. Leucowel Injection is usually given in combination with another anticancer medicine as a part of combination therapy to treat colorectal cancer.
Chemotherapy
Leucowel 15mg/2ml Injection is a prescription-based medicine used in the treatment and management of harmful side effects of methotrexate. The active ingredient of the Leucowel is Leucovorin Calcium Injection IP, which belongs to the drug class of folic acid analogs. It is administered as an injection by an experienced nurse or medical professional. Leucowel Injection works by preventing the side effects & overdose toxicity of methotrexate, treatment of anemia, and colorectal cancer. The required dosage and duration of the medicine are decided by the doctor. This depends on the disease being treated and the stage of the disease. The doctor will check medical history, age, health condition, and the body's response to the treatment before prescribing this medicine. Taking it in the wrong way or overdosing can cause severe side effects. It may take weeks for patients to notice the benefits of the medicine. So do not stop taking this injection until your doctor says to do so.
Leucowel 15mg/2ml Injection is prescribed to minimize the effect of anticancer medication, but this drug can also lead to some undesired symptoms. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Leucowel Injection are mentioned below:
Fatigue
Diarrhea
Seizures
Dizziness
Sore mouth
Skin inflammation
Nausea and vomiting
difficulty breathing or swallowing
Pain, swelling, and redness at the injection site
Leucowel 15mg/2ml Injection is a prescription-based drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Leucowel 15mg/2ml Injection is a prescription-based medicine that belongs to the drug class of folic acid antagonists. This injection is a constituent form of Vit B12. It inhibits the activity of the dihydrofolate reductase enzyme to prevent the side effects of methotrexate. This injection also protects normal healthy cells from the toxicity of the anticancer medicines and increases therapeutic effects to kill the cancer cells in colorectal cancer. Leucowel also supplies folic acid to bone marrow that supports the formation of red blood cells and eventually treats anemia.
Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Leucowel 15mg/2ml Injection. It is advised to consult your doctor for further information.
Pregnancy
consult your doctor
Leucowel 15mg/2ml Injection may be considered unsafe during pregnancy. Please consult your doctor in such condition.
Breast Feeding
consult your doctor
Leucowel 15mg/2ml Injection is probably not safe if you're breastfeeding. Kindly consult your doctor.
Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Leucowel 15mg/2ml Injection.
Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Leucowel 15mg/2ml Injection.
Liver
safe if prescribed
Inform your doctor before starting Leucowel 15mg/2ml Injection if you have liver disease to avoid any serious side effects.
It is advised not to miss any scheduled dosage of Leucowel 15mg/2ml Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to take Leucowel 15mg/2ml Injection 24 hours after the anticancer drug.
Share with your doctor if you're intolerant to some sugar, as Leucowel Injection contains a sugar constituent.
Avoid taking Leucowel 15mg/2ml Injection if you are allergic to Leucovorin Calcium Injection IP and its constituents.
It is advised to take consultation with your doctor if you are suffering from Vit B12 deficiency or certain type of anemia.
It is advised to use effective birth control methods and avoid pregnancy during the treatment with Leucowel 15mg/2ml Injection.
Share with your healthcare expert if you're taking any anti-seizure medication. They may interact with the Leucowel 15mg/2ml Injection and may lead to severe side effects.
If you experience any kind of symptoms after taking Leucowel 15mg/2ml Injection, like trouble breathing, skin rash, or swelling in the lips, face, or tongue, it is important to inform your doctor as soon as possible.
It can take some time to show positive results. It depends on the patient's diagnosed stage, medical condition, and doses.
Your healthcare expert will monitor the level of serum concentration, conduct a CBC test to check the blood count and monitor calcium levels to prevent hypercalcemia (excess calcium in the blood).
Yes, taking Leucowel Injection may cause some mild to severe allergic reactions like swelling, rashes, trouble breathing, and vomiting.
This injection is prescribed by doctors to treat various medical conditions, including; managing the side effects of immunosuppressant cancer drugs, prevention of toxicity due to overdose of methotrexate, and treatment of anemia & colorectal cancer.
If you are taking any prescribed or non-prescribed medicine while on treatment with this injection, they may interact and may cause seizures. It does not cause seizures without any other drug interaction. Take proper consultation with your doctor before taking Leucowel Injection.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.