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1 Injection
Methotrexate
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Overview
Plastomet 1000mg Injection is a prescription-based medicine primarily used to treat rheumatoid arthritis in adults. It mainly helps to stop further damage to joints and reduces inflammation. This medicine is also used to treat psoriasis, Crohn's disease, and certain types of cancer. These cancers are acute lymphocytic leukemia (ALL), meningeal leukemia, non-Hodgkin lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer.
Rheumatoid Arthritis, Cancer Medicines
Plastomet 1000mg Injection is used in the treatment of Rheumatoid Arthritis, Cancer, and severe forms of a skin disease known as psoriasis. The active ingredient of Plastomet is Methotrexate, which belongs to the drug class of antimetabolites. It is administered as an injection by an experienced nurse or medical professional subcutaneously. Plastomet Injection works by eradicating any type of inflammation in the human body. In this way, it prevents the infection from spreading to other parts of the body. The required dosage and duration of the medicine are decided by the doctor. This depends on the type of disease being treated. The doctor will check medical history, age, health condition, and the body's response to the treatment before prescribing this medicine. Taking it in the wrong way or overdosing can cause severe side effects. It may take weeks for patients to notice the benefits of the medicine. So do not stop taking this tablet until your doctor says to do so.
The human body shows undesired symptoms after taking Plastomet 1000mg Injection. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Plastomet Injection are mentioned below:
Rash
Hair loss
Diarrhea
Nausea
Vomiting
Dizziness
Blurred vision
Photosensitivity
Low WBC and platelet count
Serious side effects are:
Chest pain
Allergic reactions
Muscle weakness
Spitting or coughing blood
Weakness on one side of the body
Plastomet 1000mg Injection is a prescription-based drug used in treating Arthritis, Cancer, and Severe skin disorders. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Plastomet 1000mg Injection treats different types of diseases and works differently while treating them. It acts as an immunosuppressant while treating Rheumatoid arthritis and Crohn's disease. It means this medicine reduces the activity of the body's immune system for autoimmune disorders. It decreases swelling, pain, and stiffness in the body and works on improving function. In the case of Psoriasis, it slows down the growth of skin cells. While treating Cancer, it inhibits the multiplication of cancer cells by blocking the activity of a specific enzyme that is responsible for making new cells.

Alcohol
consult your doctor
The interaction of alcohol with Plastomet is not known. It is advisable not to consume alcohol while taking Plastomet 1000mg Injection. It is advised to consult your doctor for further information.

Pregnancy
consult your doctor
Plastomet 1000mg Injection may be considered unsafe during pregnancy. Please consult your doctor in such a condition.

Breast Feeding
consult your doctor
Plastomet 1000mg Injection is probably not safe if you're breastfeeding. Kindly consult your doctor.

Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Plastomet 1000mg Injection.

Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Plastomet 1000mg Injection.

Liver
safe if prescribed
Inform your doctor before starting Plastomet 1000mg Injection if you have liver disease to avoid any serious side effects.
It is advised not to miss any scheduled dosage of Plastomet 1000mg Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to drink plenty of liquids to stay hydrated while taking this medicine, as Diarrhea is one of the common side effects observed after taking Plastomet.
It is advised to use effective birth control methods to avoid pregnancy. Some hepatitis drugs can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine.
It is advised to tell your doctor about all medicines (multivitamins, herbal supplements) you're taking currently before starting your course with Plastomet medicines. There are chances that many drugs can interact, and some drugs should not be used together.
Yes, there are chances that this drug may affect fertility in both genders. It may reduce sperm count in males and disturb the menstrual cycle in females. These effects are reversible and disappear after discontinuing the medicine.
It is important to go for regular blood tests as it helps the doctor to examine the response of the body after taking Plastomet Injection. Keeping a check on liver function and blood count helps to maintain normal functioning of the body.
The duration and dosage of the medicine are decided by the healthcare professional. This medicine will be taken by the patient until their disease condition is treated.
A person should take a well-balanced diet, along with all other prescribed medications, such as supplements, if prescribed by the doctor. Get adequate sleep for proper recovery of the body, go for walks, and practice meditation.
Common side effects after taking Plastomet are hair loss, photosensitivity, rash, diarrhea, nausea, vomiting, decreased WBC and platelet count, dizziness, tiredness, fever, shivering, and blurred vision. Consult your doctor if these side effects persist for a longer period and are causing severe health problems.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.

Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.