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1 Injection
Leucovorin Calcium Injection IP
Keep in cold place
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Overview
Recovorin 50mg/5ml Injection belongs to the category of folic acid analogs. This medicine is primarily used to reduce harmful side effects of methotrexate. It performs multiple functions like acting as an immunosuppressant, treat anemia, and given to the patients who have accidently taken the overdose of methotrexate. Recovorin Injection is usually given in combination with another anticancer medicine as a part of combination therapy to treat colorectal cancer.
Chemotherapy, kill cancer cells
Recovorin 50mg/5ml Injection is a prescription-based medicine used in the treatment and management of the harmful side effects of methotrexate. The active ingredient of the Recovorin is calcium Leucovorin, which belongs to the drug class of folic acid analogs. It is administered as an injection by an experienced nurse or medical professional. Recovorin Injection works by preventing the side effects & overdose toxicity of methotrexate, treatment of anemia, and colorectal cancer. The required dosage and duration of the medicines are decided by the doctor. This depends on the disease being treated and the stage of the disease. The doctor will check medical history, age, health condition, and the body's response to the treatment before prescribing this medicine. Taking it in the wrong way or overdosing can cause severe side effects. It may take weeks for patients to notice the benefits of the medicine. So do not stop taking this injection until your doctor says to do so.
Recovorin 50mg/5ml Injection is prescribed to minimize the effect of anticancer medication, but this drug can also leads to some undesired symptoms. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Recovorin Injection are mentioned below:
Fatigue
Diarrhea
Seizures
Dizziness
Sore mouth
Skin inflammation
Nausea and vomiting
difficulty breathing or swallowing
Pain, swelling, and redness at injection site
Recovorin 50mg/5ml Injection is a prescription-based drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Recovorin 50mg/5ml Injection is prescription based medicine that belongs to the drug class of folic acid antagonists. This injection is a constituent form of Vit B12. It inhibits the activity of dihydrofolate reductase enzyme to prevent the side effects of methotrexate. This injection also protects normal healthy cells from toxicity of methotrexate and increases therapeutic effects to kill the cancer cells in colorectal cancer. It also supply folic acid to bone marrow that supports the formulation of red blood cell and eventually treats anemia.
Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Recovorin 50mg/5ml Injection. It is advised to consult your doctor for further information.
Pregnancy
consult your doctor
Recovorin 50mg/5ml Injection may be considered unsafe during pregnancy. Please consult your doctor in such condition.
Breast Feeding
consult your doctor
Recovorin 50mg/5ml Injection is probably not safe if you're breastfeeding. Kindly consult your doctor.
Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Lederle Recovorin 50mg/5ml Injection.
Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Recovorin 50mg/5ml Injection.
Liver
safe if prescribed
Inform your doctor before starting Recovorin 50mg/5ml Injection if you have liver disease to avoid any serious side effects.
It is advised not to miss any scheduled dosage of Recovorin 50mg/5ml Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to take Recovorin 50mg/5ml Injection 24 hours after the anticancer drug.
Share with your doctor if you're intolerant to some sugar, as Recovorin contains some sugar constituents.
Avoid taking Recovorin 50mg/5ml Injection if you are allergic to Leucovorin calcium and its constituents.
It is advised to take consultation with your doctor if you are suffering from Vit B12 deficiency or certain type of anemia.
It is advised to use effective birth control methods and avoid pregnancy during the treatment with Recovorin injection.
Share with your healthcare expert if you're taking any anti-seizure medication. They may interact with the Recovorin Injection and may lead to severe side effects.
If you experience any kind of symptoms after taking Recovorin Injection, like trouble breathing, skin rash, or swelling in the lips, face, or tongue, it is important to inform your doctor as soon as possible.
This injection is prescribed by doctors to treat various medical conditions, including managing the side effects of immunosuppressant cancer drugs, prevention of toxicity due to overdose of methotrexate, and treatment of anemia & colorectal cancer.
Your healthcare expert will monitor the level of serum concentration, CBC test to check the blood count, and monitor calcium levels to prevent hypercalcemia (excess calcium in the blood).
If you are taking any prescribed or non-prescribed medicine while on treatment with this injection, they may interact and may cause seizures. It does not cause seizures without any other drug interaction. Take proper consultation with your doctor before taking Recovorin.
It can take some time to show positive results. It depends on the patient's diagnosed stage, medical condition, and doses.
Yes, taking Recovorin may cause some mild to severe allergic reactions like swelling, rashes, trouble breathing, and vomiting.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.