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Natco
28 Tablet in Bottle
Afatinib
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Overview
Afanat 40mg tablet is a chemotherapy-based anticancer medication that is prescribed to treat non-small cell lung cancer. The generic name of this medication is Afatinib. Afatinib is the first-line treatment for non-small cell lung cancer. It is usually prescribed to patients with the EGFR gene mutation.
Lung Cancer
Afanat 40mg tablets may cause some side effects that vary from one patient to another. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.
Common side effects include:
Diarrhea
Nausea
Vomiting
Fever
Cough
Nose bleeds
Dry skin
Acne
Nose bleeds
Weight gain
Blisters of skin
Loss of appetite
Cracked or swollen lips
Rashes due to sun exposure
Dark coloration of urine
Shortness of breath
Eye pain
Increased bruises
Irregular heart rate
Seek medical attention in case of any unusual or severe side effects immediately.
The doctor determines the dosage and duration of Afanat 40mg tablets as per the patient's health condition and other medical factors. This tablet is usually taken orally on an empty stomach. Follow your doctor's instructions properly during the treatment. Don't overdose or miss a dose.
Alcohol
caution
The interaction of alcohol with this drug is still unknown, but you should avoid the consumption of alcohol while taking Afanat 40mg tablets
Pregnancy
consult your doctor
Do not take Afanat 40mg tablet during pregnancy, as it is a highly unsafe medicine for the fetus.
Breast Feeding
consult your doctor
Afanat 40mg tablet is unsafe to use during breastfeeding as it may cause toxicity to the baby.
Driving
danger
Afanat 40mg tablets may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Kidney
caution
Consumption of Afanat 40mg tablets should be avoided without informing the doctor if you have any kidney-related issues.
Liver
caution
Consumption of Afanat 40mg tablets should be avoided without informing the doctor if you have any liver-related issues.
It is advisable to avoid missing any doses. In case you miss a dose of Afanat 40mg tablets consult your doctor immediately.
Afanat 40mg tablet is an anticancer medicine that is used in the treatment of non-small cell lung cancer.
It is advisable to avoid the Afanat 40mg tablet during pregnancy as it can cause harm to the fetus.
It is advisable to avoid driving and operating heavy machinery while taking Afanat 40mg tablets, as it may cause dizziness.
The doctor decides the course of treatment with Afanat 40mg tablets depending on the stage of the cancer and the health of the patient.
Afanat 40mg tablets should be taken orally without meals. However, it is advisable to follow the prescription given by the doctor.
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1. Joshi, M., Rizvi, S. M., & Belani, C. P. (2015). Afatinib for the treatment of metastatic non-small cell lung cancer. Cancer management and research, 75-82.
2. Kumar, S., & Agrawal, R. (2014). Next generation tyrosine kinase inhibitor (TKI): afatinib. Recent patents on anti-cancer drug discovery, 9(3), 382-393.
3. Kim, Y., Lee, S. H., Ahn, J. S., Ahn, M. J., Park, K., & Sun, J. M. (2019). Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer Association, 51(2), 502-509.
4. Giordano, P., Manzo, A., Montanino, A., Costanzo, R., Sandomenico, C., Piccirillo, M. C., ... & Morabito, A. (2016). Afatinib: An overview of its clinical development in non-small-cell lung cancer and other tumors. Critical reviews in oncology/hematology, 97, 143-151.
5. Saber, A., Hiltermann, T. J. N., Kok, K., & Groen, H. J. M. (2016). Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature. Critical reviews in oncology/hematology, 100, 107-116.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.