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Prescription Required
emcure
30 tablets
Dolutegravir
Keep in cold place
Delivering To:
Overview
Instgra 50mg Tablet is a member of the class of medications known as antiretrovirals. AIDS (acquired immunodeficiency syndrome) is a disease caused by the human immunodeficiency virus, or HIV. Dolutegravir is the active component of Instgra tablets. It is a tiny chemical HIV-1 integrase inhibitor that prevents the viral genome from integrating into the host cell by blocking the strand transfer process. It eliminates your infection and stops viruses from growing in human cells. The Instgra Tablet simply helps to lower the level of HIV in your body; it is not a treatment for HIV or AIDS. This expands your life expectancy and reduces your risk of developing HIV-related illnesses. It is given together with the HIV medications as suggested by your physician.
HIV infection
HIV infection
The following are the possible side effects that can occur during your treatment with Instgra 50mg Tablet. Contact your medical practitioner immediately if any of the above-mentioned side effects appear.
Headache
Insomnia
Nausea
Fatigue
Muscle pain
Skin rash
Fever
Chills
Mouth sores
Loss of appetite
Stomach ache
Difficulty in breathing
Swelling on the face, hands, or legs
Instgra tablet (50 mg) is used in the treatment of HIV (Human Immunodeficiency Virus). It is not a permanent cure, but it is used to prevent the multiplication of the virus in the body. It should be taken regularly at the right time. It is advisable not to skip the doses. Also, do not stop taking this medicine unless your healthcare provider tells you.
Instgra 50mg Tablet, comprising Dolutegravir, is an HIV-1 antiviral agent. It works to inhibit HIV integrase and binds to the active site. It blocks the strand transfer step of retroviral DNA integration in the host cell. During the clinical trials, it was indicated that Dolutegravir has a tight binding and longer dissociative half-life. Therefore, it is indicated in combination with other antiretroviral agents for the treatment of patients with HIV-1 infection, provided their age is 12 or above and their present weight is at least 40 kg.
Alcohol
unsafe
Do not consume alcohol while taking Instgra 50mg Tablet.
Pregnancy
consult your doctor
Do not take Instgra 50mg Tablet without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Do not take Instgra 50mg Tablet if you're breastfeeding. Consultation of the doctor is advised.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of Instgra 50mg Tablet.
Kidney
precaution
Do not take Instgra 50mg Tablet without a doctor's consultation in case of kidney problems.
Liver
precaution
Do not take Instgra 50mg Tablet without a doctor's consultation in case of liver problems.
If you miss a dose, it is advisable to consult your healthcare provider to get the needed help. Also, make sure to not double the dose strength to catch up.
Instgra (Dolutegravir 50mg) tablet belongs to the class of drugs known as integrase inhibitors. It is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection.
Instgra tablet is available in a strength of 50 mg.
The side effects of Instgra 50mg Tablet are fever, chills, mouth sores, vomiting, stomach pain, yellowing of the skin or eyes, nausea, muscle or joint pain, loss of appetite, etc. Make sure to consult a medical practitioner.
After taking the Instgra 50mg Tablet, avoid driving or operating heavy machinery if side effects like blurred vision or dizziness occur and last longer than usual.
During pregnancy or breastfeeding, taking the Instga tablet may not be safe. Kindly consult your doctor to discuss the potential risks and benefits of taking this medicine.
Take the Instgra 50mg Tablet right away if you miss a dose. However, skip the missing dose and continue your usual dosing plan if your next dose is almost here.
Worsening hepatitis B, bone loss, kidney damage, pancreatitis, immunological reconstitution syndrome, liver toxicity, and hypersensitivity responses are a few of the severe adverse effects of using Instgra 50mg Tablet.
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Dravid, P., Elica K., Sharma, S., Gupta, A., Roy, A., Basu, S., Singh, S. (2022). A Phase IV study on safety, Tolerability, and efficacy of dolutegravir, lamivudine, and tenofovir disoproxil fumarate in treatment‑naïve adult Indian patients living with HIV‑1. Clinical Infectious Diseases.Published online.https://pubmed.ncbi.nlm.nih.gov/35975180/
Marchand, C. (2012). The elvitegravir Quad pill: the first once-daily dual-target anti-HIV tablet. Expert opinion on investigational drugs, 21(7), 901-904. Gandhi Medicos. (2024). Navigating HIV management with Instgra Tablet: What you need to know. Gandhi Medicos Blog. Retrieved from https://www.gandhimedicos.in/blog/understanding‑instgra‑tablet/
Panel on Antiretroviral Guidelines for Adults and Adolescents. (2024). Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. Department of Health and Human Services Services. Retrieved from https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-arv
Dravid, A., Morkar, D., Prasad, D., Ramapuram, J. T., Patel, K. V., Naik, K. S., Hegde, S. (2022). A phase IV study on safety, tolerability, and efficacy of dolutegravir, lamivudine, and tenofovir disoproxil fumarate in treatment-naïve adult Indian patients living with HIV-1. Pragmatic and Observational Research, 13, 75–84. https://doi.org/10.2147/POR.S361907
Walmsley, S. L., Antela, A., Clumeck, N., Duiculescu, D., Eberhard, A., Gutiérrez, F., … Schapiro, J. M. (2013). Dolutegravir plus abacavir–lamivudine for the treatment of HIV-1 infection. New England Journal of Medicine, 369(19), 1807–1818. https://doi.org/10.1056/NEJMoa1215541
