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emcure
28 tablet
Sofosbuvir
Keep in cold place
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Overview
Sofocure tablet is an antiviral medicine. This medicine is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults. Sofocure should be taken exactly as prescribed by the healthcare provider (in dose and duration). It works by lowering the multiplication of the virus and helps in the removal of the virus from the blood over a period of time.
Hepatitis C
Sofosbuvir inhibits the hepatitis C NS5B protein. Sofosbuvir appears to have a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, whereby the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.
Sofocure tablets may cause certain side effects. If side effects occur after administration or last longer than usual, contact your healthcare professional.
Tiredness
Confusion
Dizziness
Headache
Weakness
Joint pain
Fever
Chills
Muscle pain
Irritability
Skin rash
Itching
Fatigue
Insomnia
Take the Sofocure tablet exactly as your healthcare provider tells you. Do not alter the dose strength. Do not chew, crush, or break the tablet. Swallow the tablet as a whole.
Seek emergency medical attention in case of overdose.

Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.

Pregnancy
consult your doctor
Do not take Sofocure tablet without consulting the doctor, in case of pregnancy.

Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.

Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.

Kidney
caution
Do not take Sofocure tablet without a doctor's consultation in case of kidney problems.

Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
It is advisable not to miss any dose. In case you miss a dose of Doxilyd 10mg injection consult your doctor soon.
Missing the dose will impact the overall health of the patients. So, it is always advisable to follow the prescription of the doctor strictly.
Sofocure is an antiviral medication, used with other medicines to treat chronic Hepatitis C Virus.
Take Sofocure exactly as your healthcare provider tells you. Do not alter the dose, unless your healthcare provider tells you.
There can be side effects such as fever, chills, diarrhea, dizziness, nausea, anemia, skin rash, itching, and irritability. Please consult your healthcare provider if you experience these or any other side effects.
Store at room temperature (10-30°C). Keep it away from children, direct light, heat, and moisture.
Sofocure may cause side effects such as tiredness and blurred vision. Therefore, avoid driving and operating heavy machines if you feel unwell.
emcure

Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.

Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.