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Aprazer Healthcare Pvt Ltd
30 Tablet
Tenofovir Disoproxil Fumerate
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Overview
Tudobest 300mg Tablet is a prescription-based antiretroviral medicine used in the treatment of HIV (human immunodeficiency virus) and HBV (hepatitis B virus) infections. This medicine increases the immunity to fight against such severe diseases. Tudobest Tablet is given to adults and teenagers from 12 to 18 years old. Adolescents with HIV infection are given this medicine because they have already been treated with other HIV medicines that are less effective due to resistance or have resulted in severe side effects. Moreover, the impact of Tudobest has not been studied in people above 65 years.
HIV, Hepatitis B
The human body shows undesired symptoms after taking the Tudobest 300mg Tablet. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Common side effects include:
Rash
Diarrhea
Nausea
Vomiting
Infection
Weakness
Dizziness
Bloating
Headache
Tiredness
Stomach pain
Drowsiness
Low phosphate levels in the blood
Serious side effects are:
Kidney damage
Pancreas problems
Difficulty breathing
Lactic acidosis
Inform your doctor immediately if you experience any persistent or unusual side effects.
The doctor determines the dosage and duration of treatment with Tudobest 300mg Tablet as per the patient's health condition. It is advised to take this medicine after consulting your healthcare expert. This medicine should be taken orally at the same time every day. Please do not crush or chew the medicine and eat it as a whole with water.
The active ingredient of Tudobest is Tenofovir Disoproxil Fumarate, which belongs to the drug class of nucleoside reverse transcriptase inhibitors (NRTIs). It works by inhibiting the replication process of HIV infection. It improves the immune system of the patient to fight against infection, controls the virus production, reduces the viral load in the body and slows down the growth of this disease, and works on overall health.

Alcohol
consult your doctor
Avoid the consumption of alcohol while taking Tudobest 300mg Tablet, as alcohol can reduce the effectiveness of the medicine and worsen the symptoms

Pregnancy
consult your doctor
Do not take Tudobest 300mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.

Breast Feeding
consult your doctor
Tudobest 300mg Tablet is unsafe to use during breastfeeding as it may cause toxicity to the baby.

Driving
unsafe
Tudobest 300mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.

Kidney
safe if prescribed
Tudobest 300mg Tablet is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.

Liver
safe if prescribed
Consumption of Tudobest 300mg Tablet should be avoided without informing the doctor if you have any liver-related issues.
It is advised not to miss any scheduled dosage of the Tudobest 300mg. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to use effective birth control methods to avoid pregnancy. Some drugs can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine. Moreover, this medicine may pass to the unborn baby.
Consult your doctor if you observe symptoms such as abdominal pain, loss of appetite, dark urine, or yellowing of the eyes or skin. These symptoms indicate the presence of Jaundice in the body.
It is advised to tell your doctor about all medicines (multivitamins, herbal supplements) you're taking currently before starting your course with Tudobest 300mg. There are chances that many drugs can interact, and some drugs should not be used together.
Inform your healthcare expert in case of a history of severe blood infection, active tuberculosis, liver problems, or any serious health disorder.
Birth control is mandatory in order to avoid transmission of HIV infection to your partner and to avoid an unwanted pregnancy.
No, this medicine is not a permanent cure for HIV. It is an antiretroviral medication that helps to inhibit the multiplication process of the virus and slows down the growth of the disease. It is given as a combination therapy to manage the HIV infection lifetime.
Yes, the Tudobest 300mg is an antiretroviral drug belonging to the drug class of nucleoside reverse transcriptase inhibitors (NRTIs).
Common side effects of taking this medicine are rash, diarrhea, nausea, vomiting, infection, weakness, dizziness, bloating, headache, and tiredness.
Take this tablet at fixed time every day exactly in a dose prescribed by the doctor.
1. Nelson, M. R., Katlama, C., Montaner, J. S., Cooper, D. A., Gazzard, B., Clotet, B., ... & Rooney, J. F. (2007). The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years. Aids, 21(10), 1273-1281.
2. Lyseng-Williamson, K. A., Reynolds, N. A., & Plosker, G. L. (2005). Tenofovir disoproxil fumarate: a review of its use in the management of HIV infection. Drugs, 65(3), 413-432.
3. Kearney, B. P., Flaherty, J. F., & Shah, J. (2004). Tenofovir disoproxil fumarate: clinical pharmacology and pharmacokinetics. Clinical pharmacokinetics, 43(9), 595-612.
4. Wassner, C., Bradley, N., & Lee, Y. (2020). A review and clinical understanding of tenofovir: tenofovir disoproxil fumarate versus tenofovir alafenamide. Journal of the International Association of Providers of AIDS Care (JIAPAC), 19, 2325958220919231.
5. Gallant, J. E., & Deresinski, S. (2003). Tenofovir disoproxil fumarate. Clinical Infectious Diseases, 37(7), 944-950.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.

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Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.