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NUBLAST 100MG, 20MG CAPSULE

Mfd. by :- Cadila (Fulfilled By : Magicine Pharma)

Nublast 100mg, 20mg Capsule

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

Don't have Prescription ?

Brand name – Nublast

Generic name – Temozolomide

Manufacturer – Cadila

Strength – 20mg, 100mg

Dosage Form – Capsule

Composition – Temozolomide

Indication – Brain tumour

Storage – 2° – 8° C

 

Overview

Nublast 100mg / 20mg capsules is an anticancer medication that is used to treat specific brain tumours. The generic name of this medication is Temozolomide.  It is an alkylating agent which shows cytotoxic effects against the tumours as it is able to cross the blood-brain barrier. It is a prescription-based medication that whose course and dosage are decided by the doctor.

Pharmacodynamics

Nublast Capsule is used in the treatment of Glioblastoma. It is formed as a prodrug which changes to the active form in the body.  It can easily cross the blood-brain barrier and shows an alkylating effect by incorporating the strands of DNA and RNA. As a result, it damages the DNA strands. In addition, it shows immuno-modulatory effects as it regulates the production of immune cells.

SIDE EFFECTS

  • Constipation
  • Diarrhea
  • Extreme fatigue
  • Hair loss
  • Dizziness
  • Trouble in sleeping 
  • Loss of appetite
  • Sores in mouth and throat
  • Seizures
  • Pink and dark colouration of urine
  • Shortness of breath
  • Decrease in urine
  • Rashes
  • Fever and sore throat
  • Yellowing of skin and eyes
  • Increased bleeding
  • Bruises
  • Vision complications
  • Problems in memory

DOSAGE

Nublast 100mg / 20mg capsules are taken orally once every day on an empty stomach.

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Nublast capsules consult your doctor immediately.

Overdose

In case of an overdose on Nublast 20mg (100mg), immediately contact your doctor or any healthcare provider and seek medical attention.

WARNINGS

  • Nublast 100mg capsules can cause an allergic reaction in some patients hence it becomes mandatory to check all the ingredients list before starting the use.
  • Tell the doctor about the vitamin and mineral supplements and prescription and non-prescription medicine you take since they can interact with Nublast and block its mechanism.
  • It is advisable to avoid pregnancy and breastfeeding during the treatment since Nublast can cause harm to the fetus.
  • Nublast decreases fertility in male patients.
  • Also, avoid alcohol and driving during the treatment with Nublast capsules.
  • Tell the doctor if you have – liver or any kidney impairment.

Q - What is Nublast?

Ans – Nublast 100mg /20mg is an anticancer capsule that is primarily used for treating brain tumours.

Q - How can I take Nublast capsules?

Ans – Take Nublast capsules once every day without food.

Q – From where can I purchase Nublast 100mg /20mg capsules?

Ans – It is advisable to purchase Nublast capsule 100mg/20mg from Magicine Pharma at an affordable price.

Q - Where to store Nublast capsules?

Ans - It is advisable to store the Nublast capsules at a low temperature.

Q - Can I drink alcohol with Nublast 100mg?

Ans – It is advisable to avoid alcohol during the treatment with Nublast even though no interactions of the two are known.

Q - How long is the treatment with Nublast capsules?

Ans - The doctor decides the course of the treatment with Nublast depending on the stage of cancer and condition of the patient.

Q - Can I drive after consuming Nublast 20mg capsules?

Ans - It is advisable to avoid driving and operating heavy machinery as Nublast capsules cause dizziness as one of the side effects.

Q - Is it safe to take Nublast during pregnancy?

Ans – It is advisable to avoid pregnancy during treatment with Nublast since it can harm the fetus and also decrease fertility in men.

Q - What is the strength of Nublast?

Ans – Nublast is available in the strengths of 20mg and 100mg.

REVIEW

Interactions

With medicines

Nublast can interact with some other prescription and non-prescription medicines and interfere with each other’s workings or increase the side effects.

  • Adalimumab
  • Clozapine
  • Ketoconazole
  • Natalizumab
  • Thalidomide
  • Tofacitinib

With disease

Nublast can interact with some disease like -

  • Kidney disease
  • Liver disorders
  • Urticaria
  • Myelosuppression

With alcohol

Interactions of alcohol with Nublast 20mg (100mg) are unknown.

Contraindication

Nublast 100mg /20mg capsules should not be given to patients who show allergic reactions to it.

Alternate Brands

  • Temolon
  • Glioz
  • Temoside

Reference

Temozolomide: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00853

Temozolomide: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a601250.html

Temozolomide drug interactions. Drugs.com. https://www.drugs.com/drug-interactions/temozolomide-index.html?filter=3

Above Content has been reviewed by Professionals