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XTANDI 40MG CAPSULE

Mfd. by :- Astellas (Fulfilled By : Magicine Pharma)

Xtandi 40mg Capsule

SAFE AND SECURE


Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand Name:- Xtandi  

Generic Name:- Enzalutamide 

Alternative brand: Enzalu

Manufacturer:- Astellas 

Dosage Form:- Capsules 

Strength:- 40mg 

Composition:- Enzalutamide 

Packaging:- 120 capsules

Indication:- Prostate cancer 

Storage:- Store at room temperature 

Overview of Xtandi 40mg Capsule

Xtandi 40mg Capsule are used to treat prostate cancer. Enzalutamide is a generic name for this medicine. This medicine belongs to the class of medications known as antineoplastic endocrine therapies. This medication works by blocking the effect of testosterone. Take this medicine with or without food.  Your doctor will decide the exact dosage. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately. It is advisable not to change or stop the dose without taking suggestions from your doctor. This medicine is not recommended in children and females. 

Pharmacodynamics of Xtandi 40mg Capsule (Enzalutamide) 

Enzalutamide is a competitive androgen receptor inhibitor that affects multiple stages of the signaling pathway. This inhibits androgen receptor nuclear translocation and interaction with DNA. Enzalutamide decreases proliferation and induced cell death of prostate cancer cells in vitro, and decreases tumor volume. 

Side effects of Xtandi 40mg Capsule (Enzalutamide)

This medicine may cause some unwanted side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects 

  • Headache 

  • Weakness 

  • Back pain 

  • Fatigue 

  • Chest pain 

  • Loss of appetite

  • Dizziness 

  • Fever 

  • Mouth sore

  • Muscle weakness 

  • Anxiety 

  • Depression 

  • Seizures 

  • Diarrhea 

  • Nausea 

  • High blood pressure 

  • Irregular heartbeat 

  • Difficulty in breathing 

  • Blurred vision 

  • Itching 

  • Numbness 

  • Joint pain 

  • Drowsiness 

  • Vomiting 

  • Hot flashes 

  • Skin rash 

  • Allergic reaction 

  • Bleeding 

  • Low white blood cell count 

  • Bloating 

  • Pounding in the ears 

  • Sudden weight gain 

  • Painful urination 

  • Dry skin 

Note-Immediately contact your doctor if any side effects occur

Dosage

Take this medicine as prescribed by your doctor. Do not chew or open the capsule. Take this medicine with or without food. 

Missed dose 

  •  It is advisable not to miss a dose. If you miss a scheduled dose of Xtandi 40mg capsule, contact your doctor immediately. 

Overdose 

  • In case of an overdose, the doctor will provide emergency medical treatment.

Usage of Xtandi 40mg Capsule (Enzalutamide) 

This medicine is used to treat CRPC (castrate-resistant prostate cancer, a stage where prostate cancer keeps growing) that has spread to other parts of the body. This medication prevents the action of androgens. Take this medicine orally once a day. Do not chew or open the capsule. The dose is decided by a medical advisor according to response to the treatment and your previous medical condition. Try not to miss your dosing schedule. Protect this medicine from heat and light. 

Warnings

Before starting treatment with Xtandi 40mg Capsule, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

 

  • Children and adolescents 

    • This medicine is not advisable for use in children and adolescents. 

 

Warnings for female 

  • Pregnancy

    • This medicine is not recommended in women. 

  • Breastfeeding 

    • This medicine is not recommended in women.

General warnings and precautions 

  • This medicine may cause neurological disorders. 

  • Close monitoring of kidney function is required during treatment with this medicine. 

  • This medication may increase the risk of falls, fractures, and serious injuries.

  • Avoid driving because this medicine may cause dizziness. 

  • This medicine is not for use in children, adolescents, and females. 

  • This medicine may increase the risk of high blood pressure, diabetes, and high cholesterol. 

  • Avoid physical activities that may increase the risk of bleeding. 

Cautions

  • Do not chew, crush, or open the capsule. 

  • Do not drive or operate heavy machinery. 

  • Not for use in females. 

  • Not recommended in children and adolescents. 

Q1. What is Xtandi 40mg Capsule (Enzalutamide)? 

Ans. Xtandi capsules are used to treat prostate cancer. Enzalutamide is a generic name for this medicine. This medicine belongs to the class of medications known as antineoplastic endocrine therapies. This medication prevents the action of androgens.

Q2. How does Xtandi 40mg Capsule (Enzalutamide) work? 

Ans. This medicine is used to treat CRPC (castrate-resistant prostate cancer, a stage where prostate cancer keeps growing) that has spread to other parts of the body. This medication works by blocking the effect of testosterone.

Q3. What are the side effects of Xtandi 40mg Capsule? 

Ans. Some common side effects are:- nausea, abdominal pain, headache, weakness, loss of appetite, fatigue, high blood pressure, fever, etc. 

Q4. In what strength is it available? 

Ans. It is available in the strength of 40mg. 

Q5. What should I avoid while receiving this medicine? 

Ans. This medication causes dizziness, avoid hazardous activity.

Q6. How to use an Xtandi 40mg Capsule? 

Ans. Take this medicine orally once a day with or without food. 

Q7. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q8. Does this medicine affect liver function? 

Ans. Extra caution is recommended in patients with liver disease. Close monitoring of liver function is required. 

Q9. Can I drive after taking this medicine? 

Ans. Do not drive. This medicine may cause dizziness. 

Q10. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended for women. 

Q11. Can I take this medicine during breastfeeding? 

Ans. This medicine is not recommended for women.

Q12. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q13. Does this affect kidney function? 

Ans. Please consult your doctor, before consuming this drug. 

Q14. What are the storage conditions? 

Ans. Store this medicine at room temperature. 

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor. 

Medicine interaction 

  • Pimozide 

  • Eliquis 

  • Clozapine 

  • Oxycodone 

  • Verapamil 

  • Zytiga 

Disease interaction 

  • This medicine increases the risk in patients who are suffering from kidney diseases. 

  • This medicine should be used with caution in patients with seizures. 

Alcohol interaction  

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol. 

Contraindications 

  • Xtandi capsules are not recommended for use in patients with known allergy to Enzalutamide.  

  • This medicine is contracted in patients known to be hypersensitive.

Above Content has been reviewed by Professionals