Brand Name: Azalpho
Generic Name: Azacitidine lyophilized
Composition: Azacitidine lyophilized
Indication: Blood cancer
Storage: Store at room temperature
Azalpho (Azacitidine lyophilized) injection is used in the treatment of MDS (Myelodysplastic Syndrome). It belongs to a group of medications known as antimetabolites and it is used to treat some kinds of blood cancer. This medication works by blocking the activity of an enzyme and stop the growth of cancer cells. It is important to take Azacitidine 100mg injection as prescribed by your doctor. This medication is given as an infusion into your vein under the supervision of a healthcare provider. The recommended dose of Azalpho injection is decided by a doctor according to your previous medical condition and response to the treatment.
Pharmacodynamics of Azacitidine 100mg injection
Azacitidine lyophilized is believed to exert its antineoplastic effects by causing hypomethylation of DNA and direct cytotoxicity on abnormal hematopoietic cells in the bone marrow. The concentration of Azacitidine 100mg Injection required for maximum inhibition of DNA methylation in vitro does not cause major suppression of DNA synthesis. After the administration, the effect of this medication can be observed immediately.
Usage of Azacitidine 100mg Injection
Azalpho injection is an anti-cancer medication that interferes with the growth of DNA and RNA of the cancer cells and stops them from multiplying. This medication is used to treat myelodysplastic syndrome (in which bone marrow produces abnormal blood cells). Do not self-administer Azacitidine 100mg injection. It is advised not to change your dosing schedule without taking suggestions from your doctor. Avoid drinking alcohol while having treatment with this medication. If you experience any signs and symptoms while receiving Azacitidine 100mg injection, inform your doctor immediately. Drink plenty of water and keep yourself hydrated. Regular monitoring of liver and kidney function is required during treatment with this medication.
Side effects of Azacitidine 100mg Injection
This medicine may cause some common side effects. Discuss the risks and benefits of Azalpho injection with the doctor before starting the treatment.
Note - immediately contact your healthcare provider if any side effects occur
Dosage of azacitidine 100mg injection
Take this injection as prescribed by your doctor. Your healthcare provider will give you Azalpho injection according to your medical condition.
Before starting treatment with Azalpho medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Warnings for female
Precautions while taking azacitidine 100mg injection
This medication may increase the risk of anemia.
Regular monitoring of kidney and liver function is required during treatment with this medication.
Azalpho (Azacitidine 100mg injection) increases the risk of tumor lysis syndrome.
Inform your doctor if you experience any side effects like- nausea, fever, sore throat, headache, diarrhea, blurred vision, vomiting, swollen glands, etc.
Do not drive or operate heavy machinery.
Do not self-administer.
Not safe for pregnant women.
Do not breastfeed while receiving Azacitidine 100mg injection.
Q1. What is Azalpho (Azacitidine 100mg Injection)?
Ans. Azacitidine 100mg injection is used to treat MDS (myelodysplastic syndrome). It is an anti-cancer medication that interferes with the growth of DNA and RNA of the cancer cells and stops them from multiplying.
Q2. How does Azalpho work?
Ans. Azalpho (Azacitidine lyophilized) injection works by blocking the activity of an enzyme and stop the growth of cancer cells.
Q3. What are the side effects of Azacitidine 100mg injection?
Ans. Some common side effects are:- Loss of appetite, vomiting, diarrhea, constipation, fever, chest pain, fast heartbeat, etc.
Q4. What should I avoid while receiving this medication?
Ans. Avoid contact with people who have infections and follow the advice of your healthcare provider about any restrictions on food and other activities.
Q5. How to take Azacitidine 100mg injection?
Ans. It is advisable to not self-administer Azalpho (Azacitidine lyophilized) injection. Your healthcare provider will give you this injection according to your medical condition.
Q6. What are the storage conditions?
Ans. Store this medicine at room temperature. Keep it away from direct heat and light.
Q7. Can I consume alcohol while taking Azacitidine 100mg Injection?
Ans. Please consult your doctor before consuming alcohol.
Q8. What happens if I miss a dose?
Ans. If you miss a scheduled dose of Azacitidine 100mg Injection, contact your doctor immediately.
Q9. In what strength is it available?
Ans. Azacitidine injection is available in the strength of 100mg.
Q10. Can I take Azacitidine 100mg injection during pregnancy?
Ans. This medication is not recommended during pregnancy.
Q11. What are the self-care tips?
Ans. Keep yourself hydrated and maintain good nutrition.
Q12. Does this medicine affect liver function?
Ans. Please consult your doctor before consuming this drug.
Q13. Can I drive after taking azacitidine 100mg injection?
Ans. Azalpho injection may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur.
Azacitidine 100mg injection can interact with other medications and it may increase the risk of side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
- Hepatic tumor
- Renal impairment
- Hepatic impairment
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
- Do not take this medicine if you are allergic to Azacitidine 100mg Injection.
- Azalpho injection is not recommended in patients known to be hypersensitive.
Azacitidine Interactions Checker. Drugs.com. https://www.drugs.com/drug-interactions/azacitidine.html
Azacitidine: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a620060.html
Azacitidine: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB00928