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Arechar HealthCare
1 Vial
Bortezomib
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Overview
Bortezomib 2mg Injection is an anticancer medicine that is the first potent therapeutic proteasome inhibitor. This medicine is primarily prescribed to treat multiple myeloma and mantle-cell lymphoma. It works by slowing down or stopping the growth of cancer cells. This Injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Blood Cancer
Like any other anticancer medicine, Bortezomib 2mg Injection also shows some side effects, which vary from one person to another according to various health factors. Most of them are mild, and some are serious enough to need immediate medical attention.
Some Common side effects include:
Fever
Anxiety
Diarrhea
Hair loss
Pneumonia
Mouth ulcer
Dehydration
Constipation
Muscle Cramps
Loss of Appetite
Difficulty sleeping
Stomach infection
Irregular heart rate
Nausea and vomiting
Difficulty in breathing
Weakness & Dizziness
Low Blood Cell Counts
Some Severe side effects:
Swelling in feet
Kidney dysfunction
High blood pressure
Heart rate fluctuation
Severe skin Inflammation
Contact the doctor immediately in case of any unusual or persistent side effects.
Bortecine 2mg Injection is a prescription-based anticancer drug. Dosage and duration of treatment are usually decided by the doctor according to the patient's health condition, type & stage of cancer, etc. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
Bortezomib 2mg Injection is an anticancer medicine that belongs to the drug class of proteasome inhibitors. This medicine acts by causing toxicity in cancer cells. It inhibits the action of the 26S proteasome and blocks a key cellular signaling pathway. This interference with the signaling pathway transforms the cancer cells into being sensitive to chemotherapy. It reduces the degradation of proteins within cells. Through which, this drug promotes the deposition of a specific protein while reducing the growth and proliferation of cancer cells.

Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Bortezomib 2mg Injection.

Pregnancy
consult your doctor
Bortezomib 2mg Injection is not recommended during pregnancy as it is unsafe for the developing fetus. Doctors rarely prescribe this medicine in pregnancy.

Breast Feeding
consult your doctor
Bortezomib 2mg Injection is unsafe to use during breastfeeding as it may cause toxicity to the baby.

Driving
unsafe
Bortezomib 2mg Injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.

Kidney
safe if prescribed
Consumption of Bortezomib 2mg Injection should be avoided without informing the doctor if you have any kidney-related issues. It is safe if prescribed.

Liver
safe if prescribed
Consumption of Bortezomib 2mg Injection should be avoided without informing the doctor if you have any liver-related issues. It is safe if prescribed.
It is advised not to miss any scheduled dosage of Bortecine 2mg Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
It is advised to use effective birth control ways and avoid pregnancy during the treatment with Bortecine 2mg Injection.
A person should avoid smoking while undergoing treatment with Bortecine. Smoking may reduce the effectiveness of medicine.
Skin becomes extremely sensitive after taking Bortecine 2mg Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
Swelling of hands, lips, and weight gain are some of the side effects observed after taking Bortecine 2mg Injection. To reduce them, the doctor may suggest some medication.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Bortecine 2mg Injection, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Bortecine 2mg Injection. Consult your doctor if it doesn't stop or if blood appears in your stools.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function, cholesterol level and bone mineral density (BMD) at proper intervals after taking Bortecine 2mg Injection.
In case you notice symptoms like blurred vision, difficulty breathing, cough & fever, and diarrhea while taking Bortecine 2mg Injection, consult your doctor immediately before these symptoms become severe.
If you experience any kind of symptoms after taking Bortecine 2mg Injection, like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
Bortecine 2mg Injection is not recommended for use during pregnancy because this medicine can pass from mother to baby via blood and may cause birth defects.
Bortecine Injection may cause skin irritation and blisters if it comes in direct contact with the skin, as it contains cytotoxic agents. It is advised to use gloves while using this injection to avoid any spill.
Your doctor will schedule some scans and tests to recognize the effect of the Bortecine 2mg Injection. Those results will show if the tumor has stopped spreading.
Taking an overdose of Bortezomib 2mg Injection may have some toxic effects. So take recommended doses under the supervision of a healthcare professional on time. Don't self-administer it or overdose it for any missed dose.
Yes, some individuals may experience constipation due to Bortezomib 2mg Injection. Add a lot of fiber-rich foods (like fruits, cereals, and pulses) to your diet. Drink a lot of water to keep your body hydrated. Contact your healthcare expert in case of severe constipation.
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1.https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215331s000lbl.pdf
2.https://www.ncbi.nlm.nih.gov/books/NBK519559/
3.https://medlineplus.gov/druginfo/meds/a607007.html
4. Romano, A., Chiarenza, A., Consoli, U., Conticello, C., Forte, S., Uccello, G., ... & Di Raimondo, F. (2013). Intravenous injection of bortezomib, melphalan, and dexamethasone in refractory and relapsed multiple myeloma. Annals of oncology, 24(4), 1038-1044.
5.Wu, S., Zheng, C., Chen, S., Cai, X., Shi, Y., Lin, B., & Chen, Y. (2015). Subcutaneous administration of bortezomib in combination with thalidomide and dexamethasone for treatment of newly diagnosed multiple myeloma patients. BioMed research international, 2015(1), 927105.
Arechar HealthCare
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