Bortero
Prescription Required
Manufactured By
Hetero
Pack of
1 injection
Salt Composition
Bortezomib Injection IP
Storage
Keep in cold place
Delivering To:
All Substitutes
Overview
Bortero is an anti-cancer medicine. Bortero injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. The active ingredient in Bortero is Bortezomib. Bortezomib is a dipeptide boronic acid derivative and a proteasome inhibitor. It is used in the treatment of multiple myeloma and mantle cell lymphoma. It is a reversible inhibitor of the 26S proteasome.
Indication
Blood cancer
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Description
Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins. The active site of the proteasome has chymotrypsin-like, trypsin-like, and post-glutamyl peptide hydrolysis activity. The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors. Inhibition of these degradations sensitizes cells to apoptosis. Bortezomib is a potent inhibitor of 26S proteasome, which sensitizes activity in dividing multiple myeloma and leukemic cells, thus inducing apoptosis. In addition, bortezomib appears to increase the sensitivity of cancer cells to traditional anticancer agents (e.g., gemcitabine, cisplatin, paclitaxel, irinotecan, and radiation).
Side Effects
Most side effects of the Bortero injection do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Fatigue
Anemia (low number of red blood cells)
Nausea
Vomiting
Fever
Dizziness
Diarrhea
Constipation
Decreased appetite
Low blood platelets
Peripheral neuropathy (tingling and numbness of feet and hands)
Psychiatric disturbances
Neutrophils (decrease in white blood cell count)
How To Use
Your healthcare provider will decide what dose is necessary for you, based on your existing medications. If you miss a dose, please get in touch with your healthcare provider.
Safety Advice
Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
consult your doctor
Do not take Bortero injection without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take Bortero injection without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
Missed Doses
If you miss any dose, consult your doctor. Do not take twice the dose to catch up on the missed one. This will cause severe side effects and impact your overall health and duration of treatment.
FAQs
Bortero Injection is used in the treatment of multiple myeloma.
Your healthcare provider will give you the medicine. Do not self-administer.
The side effects of Bortero injection are low blood platelets, fatigue, dizziness, fever, constipation, diarrhea, decrease in appetite, decrease in white blood cell count, nausea, vomiting, and anemia.
If you miss a dose, please contact your healthcare provider.
Avoid driving while consuming this medicine because it may lead to dizziness.
