Bortero

Prescription Required

Manufactured By

Hetero

Pack of

1 injection

Salt Composition

Bortezomib Injection IP

Storage

Keep in cold place

shipping-zone

Delivering To:

All Substitutes

Overview

Bortero is an anti-cancer medicine. Bortero injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. The active ingredient in Bortero is Bortezomib. Bortezomib is a dipeptide boronic acid derivative and a proteasome inhibitor. It is used in the treatment of multiple myeloma and mantle cell lymphoma. It is a reversible inhibitor of the 26S proteasome.

Indication

Blood cancer

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Description

Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins. The active site of the proteasome has chymotrypsin-like, trypsin-like, and post-glutamyl peptide hydrolysis activity. The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors. Inhibition of these degradations sensitizes cells to apoptosis. Bortezomib is a potent inhibitor of 26S proteasome, which sensitizes activity in dividing multiple myeloma and leukemic cells, thus inducing apoptosis. In addition, bortezomib appears to increase the sensitivity of cancer cells to traditional anticancer agents (e.g., gemcitabine, cisplatin, paclitaxel, irinotecan, and radiation). 

Side Effects

Most side effects of the Bortero injection do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.

Fatigue  

Anemia (low number of red blood cells) 

Nausea  

Vomiting 

Fever  

Dizziness  

Diarrhea  

Constipation  

Decreased appetite  

Low blood platelets 

Peripheral neuropathy (tingling and numbness of feet and hands) 

Psychiatric disturbances 

Neutrophils (decrease in white blood cell count)  

How To Use

Your healthcare provider will decide what dose is necessary for you, based on your existing medications. If you miss a dose, please get in touch with your healthcare provider. 

Safety Advice

Alcohol

Alcohol

unsafe

It is advisable not to consume alcohol while taking this medicine.

Pregnancy

Pregnancy

consult your doctor

Do not take Bortero injection without consulting the doctor, in case of pregnancy.

Breast Feeding

Breast Feeding

consult your doctor

Without a doctor's consultation, do not take this medicine if you're breastfeeding.

Driving

Driving

danger

It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.

Kidney

Kidney

caution

Do not take Bortero injection without a doctor's consultation in case of kidney problems.

Liver

Liver

caution

Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

If you miss any dose, consult your doctor. Do not take twice the dose to catch up on the missed one. This will cause severe side effects and impact your overall health and duration of treatment.

FAQs

What is Bortero injection?

Bortero Injection is used in the treatment of multiple myeloma. 

How should I take Bortero?

Your healthcare provider will give you the medicine. Do not self-administer. 

What are the possible side effects of Bortero injection?

The side effects of Bortero injection are low blood platelets, fatigue, dizziness, fever, constipation, diarrhea, decrease in appetite, decrease in white blood cell count, nausea, vomiting, and anemia. 

What happens if I miss a dose?

If you miss a dose, please contact your healthcare provider. 

What should I avoid while consuming this medicine?

Avoid driving while consuming this medicine because it may lead to dizziness. 

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MARKETER DETAILS

Hetero