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IRINOTEL 100MG INJECTION

Mfd. by :- Fresenius Kabi (Fulfilled By : Magicine Pharma)

Irinotel 100mg Injection

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand name – Irinotel

Generic name – Irinotecan

Manufacturer – Fresenius Kabi

Strength – 100mg/5ml (20mg/ml)

Dosage Form – Injection

Composition – Irinotecan

Indication – Colon and Rectum Cancer

Storage – at 20° – 25°C

 

Overview of Irinotel 100mg Injection

Irinotel 100mg/5ml injection is a chemotherapy medication that is used in the treatment of colon and rectum cancer. The generic name of this injection is Irinotecan and it is an antineoplastic enzyme inhibitor. It is not a self-administrable injection and should be injected by a doctor or an experienced nurse only.

Pharmacodynamics

Irinotel is an enzyme inhibitor as it blocks the action of topoisomerase I. This enzyme is necessary for DNA replication. As this medication binds to the DNA – topoisomerase complex it consequently stops the replication. It also leads to damaged DNA which triggers cell death. In addition, it showcases antineoplastic properties as it stops the cell growth and metastasis of the tumour cells.

  • Heartburn
  • Loss of appetite
  • Hair loss
  • Sleepiness
  • Nausea
  • Vomiting
  • Indigestion
  • Extreme fatigue
  • Chest pain
  • Rashes and hives
  • Shortness of breath
  • Difficulty in swallowing
  • Bloating
  • Swelling of arms, legs, and stomach
  • Yellowing of eyes and skin

This medicine is prescribed by the doctor thus, it is advisable to follow the prescription given.  Irinotel 100 mg/5ml is injected intravenously. It should be injected by a doctor or an experienced nurse and is not self-administrable.

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Irinotel consult your doctor immediately.

Overdose

In case of an overdose on this injection, contact your doctor or any healthcare provider and seek medical attention immediately.

  • Irinotel can cause an allergic reaction in some patients. Therefore it is necessary to read the complete composition list before injecting it. It can cause injection site reactions like redness, swelling, and rashes in some patients.
  • Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription medicines you take. 
  • Inform the doctor if you take Ketoconazole and stop taking it one week before taking the Irinotel injection.
  • Irinotel can decrease fertility in both men and women.
  • It is advisable to avoid pregnancy during and till three months after the last injection since Irinotel 100mg/5ml can cause harm to the fetus.
  • Also, avoid breastfeeding till one week after the final dose.
  • Avoiding alcohol consumption is advisable.
  • It is advisable to avoid driving and operating heavy machinery since the injection can cause dizziness as a side effect.
  • Inform the doctor about the past medical conditions –
  • Diabetes
  • Liver(hepatic) complications
  • Lung disease
  • Kidney (renal) complications
  • Fructose intolerance

Q - What is Irinotel 100mg Injection?

Ans – Irinotel 100mg/5ml is an anticancer injection that is primarily used in the treatment of colon and rectum cancer.

Q - How can I take Irinotel 100mg/5ml injection?

Ans - Irinotel 100mg/5ml injection is given intravenously by a doctor or an experienced nurse.

Q – From where can I purchase Irinotel 100mg/5ml injection?

Ans - Irinotel 100mg/5ml injection can be purchased from Magicine Pharma at an affordable range.

Q - Where to store Irinotel injection?

Ans - It is advisable to store the injection at a place below 30°C.

Q - Can I drink alcohol during the treatment with Irinotel?

Ans - Avoid drinking alcohol after getting an Irinotel injection even though no interactions of both are known.

Q - How long is the treatment with Irinotel 100mg/5ml injection?

Ans - The doctor decides the course of treatment depending on the stage of cancer and the health of the patient.

Q - Can I drive after getting an Irinotel injection?

Ans - It is advisable to avoid driving and operating heavy machinery as Irinotel 100mg/5ml causes dizziness as one of the side effects.

Q - Is it safe to inject during pregnancy?

Ans – Irinotel can harm the fetus. Hence, it is advisable to avoid the pregnancy till three months after the last dose.

Q - What is the strength of Irinotel?

Ans – Irinotel is available as an injection of strength 100mg/5ml (20mg/ml).

Irinotel can interact with other prescription and non-prescription medicines and it can affect its working. Inform the doctor if take any of the given below –

  • Ketoconazole
  • Atazanavir
  • Carbamazepine
  • Phenorbital
  • Rifampin

With disease

Some diseases may show interactions with. Hence, consult your doctor if you have any of these conditions –

  • Diabetes
  • Liver (hepatic) complications
  • Lung disease
  • Kidney (renal) complications
  • Fructose intolerance

With alcohol

Interactions of alcohol with Irinotel 100mg/5ml are unknown. However, it is still advisable to avoid alcohol consumption during the treatment.

Contraindication

Irinotel 100mg/5ml should not be injected into patients who show allergic reactions to it.

Alternate Brands

  • Irnocam
  • Irinomil
  • Torsirin
  • Rinotec
  • Campto
  • Irinores
  • Iritero

Reference

Irinotecan Injection: MedlinePlus Drug Information MedlinePlus. Available at: https://medlineplus.gov/druginfo/meds/a608043.html .

Irinotecan Uses, Interactions, Mechanism of Action | DrugBank Online. Available at: https://go.drugbank.com/drugs/DB00762 .

Above Content has been reviewed by Professionals