Kemocarb 450mg injection

Kemocarb 450mg injection

Prescription requiredRx Required

Salt Composition: Carboplatin

Expiry Date: 01/2028

Special offer

Buy at $50.11

$50.11

Inclusive of all taxes

1 injection

About The Product

  • Ovarian Cancer
  • Small Cell Lung Cancer
  • Kemocarb 450 mg injection consists of carboplatin, a type of cancer treatment that is usually taken to treat cancer of the ovaries and small cell lung cancer.
  • This medication destroys the DNA of cancerous cells and thereby prevents further multiplication of these cells.
  • Carboplatin administration occurs through an intravenous injection procedure conducted by a healthcare practitioner at a hospital.
  • This medication is usually prescribed for the treatment of ovarian and small cell lung cancers; however, it might also be used to treat some other types of cancers, including breast cancer and soft tissue sarcomas.
  • Patients receiving treatment will require close supervision during therapy, including routine tests that will monitor blood cell levels and functionality of the organs.
  • Among the side effects associated with the use of carboplatin are nausea, vomiting, diarrhea, temporary loss of hair, lethargy, and low blood cell count.

Uses

  • Ovarian cancer
  • Small-cell lung cancer

Side Effects

Most side effects of Kemocarb 450mg injection do not require medical attention, as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately. Side effects are as follows: 

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Stomatitis (inflammation of the mouth)
  • Headache
  • Fatigue / extreme tiredness and weakness
  • Anemia (low red blood cell count)
  • Low blood platelets
  • Decreased white blood cell count (neutropenia)
  • Increased liver enzymes
  • Liver failure
  • Kidney problems
  • Hearing problems
  • Fever / chills
  • Loss of taste
  • Hair loss
  • Skin rashes / itchiness
  • Allergic reactions
  • Abnormal bruising
  • Peripheral neuropathy (tingling, numbness, prickling in hands, arms, legs, or feet)
  • Breathing difficulties
  • Inflammation in lung tissues

How To Use

  • Kemocarb 450mg injection is a prescription-based medication that is given intravenously by a doctor and an experienced nurse. 

How It Works

  • Kemocarb is an alkylating agent that primarily functions by incorporating alkyl groups into the nucleotides. This, as a result, leads to the formation of DNA fragments.
  • It works by damaging the genetic material (DNA and RNA). In addition, it also prevents the strands from separating during the synthesis. Therefore, Kemocarb 450mg stops the growth and spreading of tumors.

Safety Advice

Alcohol

The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Kemocarb 450mg Injection as it may cause excessive drowsiness. Consult your doctor for further information.

Pregnancy

Kemocarb 450mg Injection may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking Kemocarb 450mg Injection during pregnancy has shown harmful effects on the developing baby.

Breast Feeding

Kemocarb 450mg Injection is probably not safe if you're breastfeeding. Kindly consult your doctor before taking Kemocarb 450mg Injection while breastfeeding, as there are chances that it may pass to the developing baby through the breast milk of the mother.

Driving

It is advisable not to drive or operate heavy machinery after taking Kemocarb 450mg Injection, as you may feel dizzy.

Kidney

Share your medical history with your healthcare expert in case of kidney disease before taking Kemocarb 450mg Injection. Patients with renal impairment must be careful while taking Kemocarb 450mg Injection. They may require adjustment in the dose.

Liver

Inform your doctor before starting Kemocarb 450mg Injection. If you have liver disease, avoid any serious side effects. Patients with hepatic impairment must be careful while taking Kemocarb 450mg Injection. They may require adjustment in the dose.

Missed Doses

  • ​It is advisable to avoid missing any dose of Kemocarb injection but in case you miss a dose consult your doctor immediately.​

FAQs

Kemocarb injection is an anticancer that is primarily used in the treatment of lung cancer.

and ovarian cancer.

References

  • A H Calvert et al. (2024). Carboplatin dosage: prospective evaluation of a simple formula based on renal function. JCO 7, 1748-56 - https://pubmed.ncbi.nlm.nih.gov/2681557/
  • Duffull SB, Robinson BA. (2025). Clinical pharmacokinetics and dose optimisation of carboplatin. Clin Pharmacokinet; 33(3):161-83 - https://pubmed.ncbi.nlm.nih.gov/9314610/
  • Huizing MT, van Warmerdam LJ, Rosing H, Schaefers MC, Lai A, Helmerhorst TJ, Veenhof CH, Birkhofer MJ, Rodenhuis S, Beijnen JH, ten Bokkel Huinink WW. (2024). Phase I and pharmacologic study of the combination of paclitaxel and carboplatin as first-line chemotherapy in stage III and IV ovarian cancer. J Clin Oncol 15(5):1953-64 - https://pubmed.ncbi.nlm.nih.gov/9164207/
  • Oguri S, Sakakibara T, Mase H, Shimizu T, Ishikawa K, Kimura K, Smyth RD. (2024). Clinical pharmacokinetics of carboplatin. J Clin Pharmacol;28(3):208-15 - https://pubmed.ncbi.nlm.nih.gov/3283185/
  • Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, (2023). Calvert AH. A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer;75(2):287-94 - https://pubmed.ncbi.nlm.nih.gov/9010040/
  • Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, Calvert AH. (2023). A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer. 75(2):287-94.
  • van der Vijgh WJ. (2022). Clinical pharmacokinetics of carboplatin. Clin Pharmacokinet. ;21(4):242-61.

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