Marketed By
fresenius kabi
Pack of
1 injection
Salt Composition
Carboplatin
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
- Kemocarb 450 mg injection consists of carboplatin, a type of cancer treatment that is usually taken to treat cancer of the ovaries and small cell lung cancer.
- This medication destroys the DNA of cancerous cells and thereby prevents further multiplication of these cells.
- Carboplatin administration occurs through an intravenous injection procedure conducted by a healthcare practitioner at a hospital.
- This medication is usually prescribed for the treatment of ovarian and small cell lung cancers; however, it might also be used to treat some other types of cancers, including breast cancer and soft tissue sarcomas.
- Patients receiving treatment will require close supervision during therapy, including routine tests that will monitor blood cell levels and functionality of the organs.
- Among the side effects associated with the use of carboplatin are nausea, vomiting, diarrhea, temporary loss of hair, lethargy, and low blood cell count.
Indication
- Ovarian Cancer
- Small Cell Lung Cancer
Uses
- Ovarian cancer
- Small-cell lung cancer
Side Effects
Most side effects of Kemocarb 450mg injection do not require medical attention, as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately. Side effects are as follows:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomatitis (inflammation of the mouth)
- Headache
- Fatigue / extreme tiredness and weakness
- Anemia (low red blood cell count)
- Low blood platelets
- Decreased white blood cell count (neutropenia)
- Increased liver enzymes
- Liver failure
- Kidney problems
- Hearing problems
- Fever / chills
- Loss of taste
- Hair loss
- Skin rashes / itchiness
- Allergic reactions
- Abnormal bruising
- Peripheral neuropathy (tingling, numbness, prickling in hands, arms, legs, or feet)
- Breathing difficulties
- Inflammation in lung tissues
How To Use
- Kemocarb 450mg injection is a prescription-based medication that is given intravenously by a doctor and an experienced nurse.
How It Works
- Kemocarb is an alkylating agent that primarily functions by incorporating alkyl groups into the nucleotides. This, as a result, leads to the formation of DNA fragments.
- It works by damaging the genetic material (DNA and RNA). In addition, it also prevents the strands from separating during the synthesis. Therefore, Kemocarb 450mg stops the growth and spreading of tumors.
Safety Advice
Alcohol
CONSULT YOUR DOCTOR
Pregnancy
UNSAFE
Breast Feeding
UNSAFE
Driving
DANGER
Kidney
PRECAUTION
Liver
PRECAUTION
Missed Doses
- It is advisable to avoid missing any dose of Kemocarb injection but in case you miss a dose consult your doctor immediately.
FAQs
Kemocarb injection is an anticancer that is primarily used in the treatment of lung cancer. and ovarian cancer.
Kemocarb injection is given intravenously by a doctor or an experienced nurse.
It is advisable to store the Kemocarb vial at a place below 30°C.
The doctor decides for how long the treatment with Kemocarb 450mg will continue depending on the condition, stage, and health of the patient.
Kemocarb injection can cause harm to the fetus; hence, it is advisable to avoid the pregnancy or consult the doctor for the same.
No, Kemocarb 450mg injection is not a cell cycle-specific anticancer medication.
Yes, Kemocarb 450mg injection contains carboplatin, which is a platinum-based drug and is effectively used in combination with other drugs.
Yes, Kemocarb 450mg injection causes side effects like hair loss, weight gain, constipation, leukemia, or hearing loss as side effects of the medicine. It is recommended to always ask your doctor about all possible side effects after taking the medicine.
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References
- A H Calvert et al. (2024). Carboplatin dosage: prospective evaluation of a simple formula based on renal function. JCO 7, 1748-56 - https://pubmed.ncbi.nlm.nih.gov/2681557/
- Duffull SB, Robinson BA. (2025). Clinical pharmacokinetics and dose optimisation of carboplatin. Clin Pharmacokinet; 33(3):161-83 - https://pubmed.ncbi.nlm.nih.gov/9314610/
- Huizing MT, van Warmerdam LJ, Rosing H, Schaefers MC, Lai A, Helmerhorst TJ, Veenhof CH, Birkhofer MJ, Rodenhuis S, Beijnen JH, ten Bokkel Huinink WW. (2024). Phase I and pharmacologic study of the combination of paclitaxel and carboplatin as first-line chemotherapy in stage III and IV ovarian cancer. J Clin Oncol 15(5):1953-64 - https://pubmed.ncbi.nlm.nih.gov/9164207/
- Oguri S, Sakakibara T, Mase H, Shimizu T, Ishikawa K, Kimura K, Smyth RD. (2024). Clinical pharmacokinetics of carboplatin. J Clin Pharmacol;28(3):208-15 - https://pubmed.ncbi.nlm.nih.gov/3283185/
- Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, (2023). Calvert AH. A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer;75(2):287-94 - https://pubmed.ncbi.nlm.nih.gov/9010040/
- Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, Calvert AH. (2023). A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer. 75(2):287-94.
- van der Vijgh WJ. (2022). Clinical pharmacokinetics of carboplatin. Clin Pharmacokinet. ;21(4):242-61.
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