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1 injection
Carboplatin
Keep in cold place
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Overview
Kemocarb 450mg injection is a chemotherapy medicine that is used for the treatment of small-cell lung cancer. It is also used in the treatment of ovarian cancer. The generic name of this medication is Carboplatin, and it is an alkylating agent. Kemocarb 450mg/45ml vial should be injected only by a doctor or a trained nurse. It works by slowing or stopping the growth of cancer. It is given as an injection into the veins under the supervision of the doctor.
Lung Cancer
Ovarian cancer
Small-cell lung cancer
Most side effects of Kemocarb 450mg injection do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately. Nausea
Diarrhea
Sores in the mouth
Burning feeling in hands and feet
Hair loss
Extreme fatigue
Dizziness Shortness of breath
Swelling of the face, arms, and feet
Difficulty in hearing
Blisters and rashes at the injection site
Decrease in urine
Vision problems
Kemocarb 450mg injection is a prescription-based medication that is given intravenously by a doctor and an experienced nurse. In case of an overdose of Kemocarb 450mg /45ml, contact your doctor or any healthcare provider and seek medical attention immediately.
Kemocarb is an alkylating agent that primarily functions by incorporating alkyl groups into the nucleotides. This, as a result, leads to the formation of DNA fragments. It works by damaging the genetic material (DNA and RNA). In addition, also prevents the strands from separating during the synthesis. Therefore, Kemocarb 450mg stops the growth and spreading of tumours.
Alcohol
unsafe
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Kemocarb 450mg Injection. Consult your doctor for further information.
Pregnancy
consult your doctor
Kemocarb 450mg Injection may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking Kemocarb 450mg Injection during pregnancy has shown harmful effects on the developing baby.
Breast Feeding
consult your doctor
Kemocarb 450mg Injection is probably not safe if you're breastfeeding. Kindly consult your doctor before taking Kemocarb 450mg Injection while breastfeeding, as there are chances that it may pass to the developing baby through the breast milk of the mother.
Driving
danger
It is advisable not to drive or operate heavy machinery after taking Kemocarb 450mg Injection, as you may feel dizzy.
Kidney
caution
Share your medical history with your healthcare expert in case of kidney disease before taking Kemocarb 450mg Injection. Patients with renal impairment must be careful while taking Kemocarb 450mg Injection. They may require adjustment in the dose.
Liver
caution
Inform your doctor before starting Kemocarb 450mg Injection. If you have liver disease, avoid any serious side effects. Patients with hepatic impairment must be careful while taking Kemocarb 450mg Injection. They may require adjustment in the dose.
It is advisable to avoid missing any dose of Kemocarb injection but in case you miss a dose consult your doctor immediately.
Kemocarb injection is an anticancer that is primarily used in the treatment of lung cancer.
Kemocarb injection is given intravenously by a doctor or an experienced nurse.
It is advisable to store the Kemocarb vial at a place below 30°C.
The doctor decides for how long the treatment with Kemocarb 450mg will continue depending on the condition, stage, and health of the patient.
Kemocarb injection can cause harm to the fetus hence, it is advisable to avoid the pregnancy or consult the doctor for the same.
No, Kemocarb 450mg injection is not a cell cycle-specific anticancer medication.
Yes, Kemocarb 450mg injection contains carboplatin, which is a platinum-based drug and is effectively used in combination with other drugs.
Yes, Kemocarb 450mg injection causes side effects like hair loss, weight gain, constipation, leukemia, or hearing loss as side effects of the medicine. It is recommended to always ask your doctor about all possible side effects after taking the medicine.
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1. A H Calvert et al. (2024). Carboplatin dosage: prospective evaluation of a simple formula based on renal function. JCO 7, 1748-56.
2. Duffull SB, Robinson BA. (2025). Clinical pharmacokinetics and dose optimisation of carboplatin. Clin Pharmacokinet; 33(3):161-83.
3. Huizing MT, van Warmerdam LJ, Rosing H, Schaefers MC, Lai A, Helmerhorst TJ, Veenhof CH, Birkhofer MJ, Rodenhuis S, Beijnen JH, ten Bokkel Huinink WW. (2024). Phase I and pharmacologic study of the combination of paclitaxel and carboplatin as first-line chemotherapy in stage III and IV ovarian cancer. J Clin Oncol 15(5):1953-64.
4. Oguri S, Sakakibara T, Mase H, Shimizu T, Ishikawa K, Kimura K, Smyth RD. (2024). Clinical pharmacokinetics of carboplatin. J Clin Pharmacol;28(3):208-15.
5. Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, (2023). Calvert AH. A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer;75(2):287-94.
6. Siddiqui N, Boddy AV, Thomas HD, Bailey NP, Robson L, Lind MJ, Calvert AH. (2023). A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. Br J Cancer. 75(2):287-94.
7. van der Vijgh WJ. (2022). Clinical pharmacokinetics of carboplatin. Clin Pharmacokinet. ;21(4):242-61.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.