Brand Name:- Keytruda
Generic Name:- Pembrolizumab
Strength :- 100mg/4ml
Dosage Form:- Injection
Packaging Size:- 1 vial
Manufacturer:- Merck sharp
Indications:- Head and neck cancer, lung cancer, skin cancer, gastric cancer
Storage:- Store in a cool and dry place
KEYTRUDA (Pembrolizumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is used with other types of medicine to cure certain types of cancers such as lung cancer, skin cancer, gastric cancer, liver cancer. This medicine is used to treat a kind of lung cancer called non-small cell lung cancer. It is an immunotherapy that works with your immune system to fight cancer. Keytruda is often given when cancer has spread to other parts of the body and cannot be treated with chemotherapy or radiation therapy. Keytruda can cause side effects in different parts of your body.
Keytruda (Pembrolizymab) indications
It is indicated for the treatment of patients with metastatic myeloma.
It is indicated for the treatment of small-cell lung cancer
It is indicated for the treatment of adult and pediatric patients with metastatic microsatellite instability-high(MSI-H).
Keytruda, in combination with axitinib, is indicated for the first-line treatment of patients with advanced renal cell carcinoma RCC.
Keytruda (Pembrolizumab) interaction
Pembrolizumab interaction with disease
Q1. What is the use of keytruda?
Ans. Pemrulizumab blocks the PD-1 (type of protein) receptor, preventing binding and activation of PD-L1 and PD-L2. This process results in the activation of T-cell mediated immune responses in contrast to tumor cells.
Q2. How does this medication work?
Ans. keytruda is a type of immunotherapy that works by blocking the PD-1 pathway and to help prevent cancer cells from hiding. Keytruda helps the immune system to detect and fight cancer.
Q3. What are the side effects of keytruda?
Ans. common side effects are vomiting, skin rash, nausea, blurred vision, dizziness, constipation, sore throat, pale skin, muscle cramps etc.
Q4.In what strengths is it available?
Ans. It is available in 100mg/4ml solution in a single dose vial.
Q5. Is keytruda an immunotherapy?
Ans. keytruda is an immunotherapy medicine that may treat certain cancers by working with your immune system. Immunotherapy is a type of cancer treatment that uses your own immune system to help detect and fight cancer.
Q6. How long does it take to effect?
Ans. It usually takes 30 minutes after you have it.
Q7.What are the signs that show keytruda is working?
Ans. It is measured by a shrinking or stable tumor. During and after treatment, the patient will have a regular checkup with his or her physician.
Q8.When should patients notify their physician?
Ans. If you have symptoms of lung problem(shortness of breath, chest pain), kidney problem and other signs of problem with other organs like:- rash, change in eyesight, severe muscle weakness.
Q9. How will I receive keytruda?
Ans. Your doctor will give you an injection into your vein. It is given every 3 weeks. Your doctor will decide how many treatments you need.
Q10. How are patients taking keytruda monitored?
Ans. Patients receiving keytruda are monitored with blood work and other laboratory tests to check the adverse reaction on the immune system like:- changes in kidney and thyroid function, hepatitis, colitis and pneumonitis.
Q11. Can I take this medicine during pregnancy?
Ans. This medication is not recommended for pregnant womens, because it may harm the unborn baby.
Q12. Can this medicine be taken during breast feeding?
Ans It is unsafe during breastfeeding, that’s why it is not recommended for breastfeeding womens.
Q13. What if I miss a dose?
Ans. Contact your doctor immediately, in case you miss a dose.
Q14. What should I avoid while receiving a keytruda?
Ans. It can pass into body fluids(urine, vomits). For 48 hours after taking a dose, avoid allowing your body fluid to come in contact with your hand or other surfaces.