LEUBEN

Mfd. by :- Hetero (Fulfilled By : Magicine Pharma)

Leuben

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Medicine Details 

Brand Name: Leuben  

Generic Name: Bendamustine  

Manufacturer: Hetero  

Dosage Form: Injection  

Strength: 100mg  

Composition: Bendamustine  

Packaging: 1 vial  

Indication: Non-Hodgkin's Lymphoma (NHL), Blood cancer, Multiple myeloma  

Storage: Store at room temperature  

Overview 

Leuben (Bendamustine) injection is used in the treatment of Non-Hodgkin's Lymphoma. This medicine belongs to a group of cancer-fighting medications known as alkylating agents. It works by killing cancerous cells and slowing down their growth. It is important to take a Leuben injection as prescribed by your doctor. Close monitoring of blood cell counts is required while having treatment with this medicine. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately. 

Pharmacodynamics 

Bendamustine is a bifunctional mechlorethamine derivative. Mechlorethamine and its derivatives form electrophilic alkyl groups. These groups form covalent bonds with electron-rich nucleophilic moieties, resulting in interstrand DNA crosslinks. The bifunctional covalent linkage can lead to cell death via several pathways.  

Usage 

This injection is also used to treat a type of cancer called chronic lymphocytic leukemia. It interferes with the growth of cancerous cells and destroys them. This medicine is given as an infusion into your vein. The recommended dose of Leuben injection is based on your medical condition and your response to the treatment. Do not self administer this medicine. Do not use Leuben (Bendamustine) if the vial is cracked. This injection affects your immune system and may increase the risk of getting infections more easily. Avoid contact with other people who have infections. It is advisable not to change or stop the dose without taking suggestions from your doctor.  

Interactions  

Leuben injection can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor. 

Medicine Interactions   

  • Clozapine  

  • Leflunomide  

  • Adalimumab  

  • Tofacitinib  

  • Deferiprone  

Disease Interactions  

  • Hepatic impairment  

  • Renal impairment  

  • Myelosuppression  

Alcohol Interaction 

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.  

Contraindications  

  • Do not take this medicine if you are allergic to Bendamustine.  

  • Leuben (Bendamustine) medicine is not recommended in patients known to be hypersensitive. 

Side effects  

This medicine may cause some serious and common side effects. Discuss the risks and benefits of the Thalix capsule with the doctor before starting the treatment. 

Common side effects  

  • Anemia  

  • Infection  

  • Headache  

  • Nausea  

  • Mouth ulcer  

  • Joint pain  

  • Vomiting  

  • Fatigue  

  • Low blood platelets  

  • Unusual weakness  

  • Loss of strength  

  • Pale skin  

  • Swollen glands  

  • Dizziness  

  • Mucosal inflammation  

  • Difficult or painful urination  

  • Unusual tiredness  

  • Weight loss  

  • Red spots on the skin  

  • Abdominal pain  

  • Muscle pain  

  • Dehydration  

  • Burning or stinging sensation  

Serious side effects  

  • Bleeding gums  

  • Chest pain  

  • Diarrhea  

  • Sore throat  

  • Irregular heartbeat  

  • Blistering and peeling of the skin  

  • Unusual bruising  

  • Fever  

  • Blood in urine  

Note - Please consult your doctor or medical practitioner if any side effects occur. 

Dosage 

Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self administer.  

Missed dose  

  • It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of Leuben injection, contact your doctor immediately.  

Overdose  

  • In case of an overdose of Leuben injection, the doctor will provide emergency medical treatment. 

Warnings 

Before starting treatment with Leuben medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

  •  Contraception  

  • Use suitable methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  •  Leuben injection is not advisable for use in children and adolescents.  

Warnings for female  

Pregnancy 

  • Do not use Leubeno medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is absolutely required. Please consult with your doctor before starting treatment with this medication. 

Precautions 

  • Avoid contact with people who have infections.  

  • Close monitoring of blood cell count is required while having treatment with this medicine.  

  • Leuben injection should be used with caution in patients who have a history of cardiovascular disease.  

  • Inform your doctor if you experience any side effects like - anemia, infection, nausea, unusual weakness, muscle pain, fever, and bleeding.  

  • Close monitoring of kidney and liver function is required while having treatment with this medicine.  

  • Do not skip the scheduled dose of this medicine.  

Cautions 

  • Do not self administer.  

  • Do not drive or operate heavy machinery. 

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication. 

Q1. What is Leuben (Bendamustine)?  

Ans. This injection is used in the treatment of Non-Hodgkin's Lymphoma. It interferes with the growth of cancerous cells and destroys them. 

Q2. How does Leuben injection work?  

Ans. It works by damaging the DNA and RNA of cancer cells and slowing down their growth.  

Q3. What are the side effects?  

Ans. Some common side effects are - low blood platelets, pale skin, fever, bleeding gums, swollen glands, dizziness, etc.  

Q4. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of Leuben injection, contact your doctor immediately. 

Q5. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision and your ability to concentrate.  

Q6. In what strength is it available?  

Ans. It is available in the strength of 100mg.  

Q7. Can I consume alcohol while receiving this medicine?  

Ans. Please consult your doctor before consuming alcohol.  

Q8. What should I avoid while receiving this medication?  

Ans. Follow your doctor’s advice about any restrictions on food and other activities. 

Q9. Can I take this medicine during pregnancy?  

Ans. This medicine is not recommended during pregnancy.  

Q10. How to take this injection?  

Ans. It is given as an infusion into the vein. Do not self administer this medicine. 

Q11. Does this medicine affect Kidney function?  

Ans. Please consult your doctor before consuming this drug. 

Q12. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary.  

Q13. Does this medicine affect liver function?  

Ans. Please consult your doctor before consuming this drug. 

Q14. What are the storage conditions?  

Ans. Store this medicine at room temperature.  

 

Above Content has been reviewed by Professionals