Marketed By
Hetero
Pack of
1 Vial
Salt Composition
Rituximab
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
- Maball 500mg Injection is used in the treatment of non-hodgkin lymphoma (NHL), rheumatoid arthritis, and blood cancer (chronic lymphocytic leukemia).
- It is an injection given under the supervision of a qualified healthcare provider.
- The active ingredient of Maball injection is Rituximab.
- It is available in a strength of 500 mg.
- It is a genetically engineered chimeric murine/human monoclonal antibody, which is directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes.
Indication
- Non-Hodgkin’s Lymphoma (NHL)
- Chronic Lymphocytic Leukemia (CLL)
- Rheumatoid Arthritis (RA)
- Vasculitis (GPA & MPA)
- Pemphigus Vulgaris
Uses
- Non-Hodgkin’s Lymphoma (NHL)
- Chronic Lymphocytic Leukemia (CLL)
- Rheumatoid Arthritis (RA)
- Vasculitis (GPA & MPA)
- Pemphigus Vulgaris
Side Effects
Maball 500mg Injection may cause certain side effects. If side effects occur after administration or last longer than usual, contact your healthcare professional. Regular blood tests are needed to monitor your blood cells and check for hepatitis B. Common side effects are:
- Headache
- Cough
- Fever
- Chills
- Hair loss
- Decrease in WBC
- Skin rash
- Insomnia
- Sore throat
How To Use
This medicine will be administered by your doctor or nurse. Do not take it on your own.
How It Works
- Maball 500mg Injection links to the CD20 antigen on both normal and malignant B‑cells.
- This binding triggers the immune system to attack and kill the tagged B‑cells.
- Stem cells, which lack CD20, survive and later regenerate healthy B‑cells after treatment.
Safety Advice
Alcohol
CONSULT YOUR DOCTOR
Pregnancy
CONSULT YOUR DOCTOR
Breast Feeding
CONSULT YOUR DOCTOR
Driving
CONSULT YOUR DOCTOR
Kidney
CONSULT YOUR DOCTOR
Liver
CONSULT YOUR DOCTOR
Missed Doses
In case you miss a dose, make sure to consult your healthcare provider to get proper guidance. Do not double the dose for compensation.
FAQs
Maball 500mg Injection is used in the treatment of non-hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (RA), vasculitis (GPA & MPA), and pemphigus vulgaris.
Common side effects include fever, chills, fatigue, nausea, diarrhea, and infections, etc. It is advised to contact your healthcare provider regarding the side effects you experience while consuming this medicine. Also, note that there can be other side effects also.
Alcohol may worsen the condition. Make sure to take advice from a healthcare provider before consuming alcohol with this medicine.
Maball 500mg Injection is not advised during pregnancy, as animal studies show potential harm to the fetus. However, a doctor may prescribe it if the expected benefits outweigh the possible risks. Use reliable contraception to prevent pregnancy while taking this medicine.
If you feel dizzy after taking Maball, make sure to avoid driving or operating heavy machines.
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References
- Feder, O., Amsterdam, D., Ershed, M., et al. (2025). Long‑term efficacy of rituximab in steroid‑dependent and frequent relapsing adult nephrotic syndrome. BMC Nephrology, 26, 126 - https://pubmed.ncbi.nlm.nih.gov/40050772/
- Kalenik, V. A., Belada, D., Oliveira, A. C., et al. (2024). Efficacy and safety of rituximab biosimilar (DRL_RI) versus MabThera® in low-tumor-burden follicular lymphoma: The FLINTER study. Blood, 144 (Supplement 1), 6276 - https://pubmed.ncbi.nlm.nih.gov/40421128/https://pubmed.ncbi.nlm.nih.gov/40421128/
- Kimby, E. K., Schär, S., Pirosa, M. C., et al. (2025). Six‑month rituximab‑lenalidomide regimen in advanced untreated follicular lymphoma: SAKK 35/10 trial 10‑year update. Blood Advances - https://pmc.ncbi.nlm.nih.gov/articles/PMC11999207/
- Maharaj, N., Uppada, D. R., Reddy, N., et al. (2024). Comparing immunogenicity and safety following transition from reference rituximab to biosimilar rituximab (DRL_RI) in patients with rheumatoid arthritis: A randomized, double‑blind, phase 3 study. Arthritis Research & Therapy, 26, 225.
- Zheng, X., Di, J., Chen, X., Li, F., Liu, Y., Cao, J., Ning, X., Wei, L., & Zheng, G. (2025). Meta-analysis of the efficacy and safety of rituximab in the treatment of primary Sjögren’s syndrome. Frontiers in Immunology, 16, 1561214.
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Hetero
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The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.

